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About Product
This content has been written and checked for quality and accuracy by
Mohamed Imran Lakhi Content Administrator GPhC: 2060586 Updated on: 26/05/2020 Next review: 26/11/2020

What is Lamisil?

Lamisil is an antifungal medicine which treats various fungal infections including athlete's foot, ringworm, jock itch and fungal nail infections.

Lamisil cream is a 1% antifungal solution for the treatment of fungal infections on the skin such as athlete's foot, ringworm or jock itch.

The Lamisil oral tablet contains 250 mg of terbinafine hydrochloride to treat infections of fingernails or toenails.

What are ringworm, jock itch, and athlete's foot?

Ringworm (tinea corporis), Dhobie itch/jock itch (tinea cruris) and athlete's foot (tinea pedis) are skin infections which are caused by fungi (dermatophytes). These types of infections are contagious and should be treated as soon as possible to avoid infecting other people.

Moreover, fungal skin infections can spread to other parts of the body. This commonly occurs with athlete's foot and fungal nail infections. The fungi of athlete's foot between the toes can spread to the toenail, resulting in a fungal nail infection. Similarly, a ringworm infection which is spread to your groin area is commonly referred to as jock itch.

Symptoms of a fungal skin infection include:

  • Bald spots on scalp
  • Blisters
  • Broken skin
  • Discolouration of nails
  • Itching skin
  • Peeling skin
  • Raised ring shaped rash
  • Scaling or flaky skin

While the condition can be uncomfortable, it is important to resist the urge of scratching infected rashes, as this increases the risk of spreading the infection to other parts of your body.

Fungal infections can be easily treated with over-the-counter and prescription medicines. Lamisil is one such treatment for fungal infections of the skin, such as ringworm, jock itch and athlete's foot.

How does Lamisil work?

Conditions that respond to Lamisil are fungus infections. Lamisil's active ingredient, terbinafine hydrochloride, inhibits squalene epoxidase in fungal cells, affecting their ability to make the sterols necessary for survival. As a result, treatment with Lamisil causes the fungal cells to die. As the infection is killed by the medicine, the related symptoms, such as itching and rash, subside.

Depending on the location on the infection, the severity of the infection, and the treatment used to treat it, the time it takes for the infection to be killed can vary from a few weeks to a few months.

Lamisil Cream

Lamisil cream is applied topically and is absorbed by the skin. The cream helps to sooth the itching caused by the infection, providing relief from the discomfort. This also indirectly helps to reduce the chances of the infection spreading to other parts of the body through scratching.

Lamisil Tablet

Lamisil tablets are taken orally. Once ingested, terbinafine hydrochloride interferes with the fungal cells ability to produce the enzyme they need to survive.

How do I take/use Lamisil?

Lamisil Cream for Adults

Follow your doctor's instruction regarding the quantity of cream to use at one time and for how long you should use this medication.

  1. Before applying the cream, cleanse the skin and pat the area dry with a clean towel. Avoid rubbing the affected area dry as this can cause unnecessary irritation.
  2. Wash your hands before touching the cream.
  3. Unscrew the lid on the Lamisil tube and squeeze out enough cream onto your finger to form a thin layer over the infected area.
  4. Apply the cream to the affected area creating a thin layer of the medication. Rub the medicine in gently to help the skin absorb the cream.
  5. For infections between the toes, such as athlete's foot, or on the groin or buttocks, such as jock itch, you may apply a light, fresh gauze.
  6. Always wash your hands after applying the cream.

If you are unsure about how much cream you should apply to your infection, ask a doctor or pharmacist for assistance.

This medication is not recommended for children.

Lamisil Tablets

Follow the doctor's instructions for dosage. The typical dose for adults is one 250 mg tablets per day. Swallow the tablet whole with a glass of water. Lamisil tablets can be taken with or without food.

It is important to continue taking Lamisil tablets for as long as the doctor tells you to. This will ensure the medicine kills the infection. Stopping treatment too soon can risk the infection coming back.

Lamisil Side Effects and Cautions

All medicines carry the risk of side effects, though not everybody experiences them. Before administering your first dose, it is important to familiarise yourself with the patient information leaflet enclosed with your medicine. If you have any concerns about anything you read in this leaflet, consult your doctor or a pharmacist for assistance.

Lamisil Cream Cautions

Tell your doctor if you are allergic to any of the ingredients in Lamisil cream including:

  • Terbinafine hydrochloride
  • Sodium hydroxide
  • Benzyl alcohol
  • Sorbitan stearate
  • Cetyl palmitate
  • Cetyl alcohol
  • Stearyl alcohol,
  • Polysorbate 60
  • Isopropyl myristate
  • Purified water

Signs of an allergic reaction from Lamisil cream include:

  • Difficulty breathing
  • DIfficulty swallowing
  • Swelling in the mouth, face, lips, tongue or throat

Seek emergency medical help immediately if you experience any of these side effects.

Cetyl alcohol and stearyl alcohol have been known to cause skin irritation. Let your doctor know if you experience any discomfort after applying this cream.

Lamisil 1% cream is only for external use. Avoid using this cream on your face and take care not to get it in your eyes. If you do get it in your eyes, immediately wash them out with running water.

Tell your doctor and pharmacist if you are currently using any other medication including over the counter products. Lamisil 1% cream is not recommended for children. Do not use Lamisil 1% cream if you are pregnant or breastfeeding.

Common side effects include:

  • Skin peeling
  • Itching

Uncommon side effects include:

  • Skin sores
  • Scabbing
  • Changes in skin colour
  • Redness on around application site
  • Burning
  • Pain or irritation around the application site

Rare side effects include:

  • Eczema - skin inflammation, blisters and itching
  • Contact dermatitis - Skin inflammation, redness, rash and itching
  • Dry skin
  • Eye irritation
  • Worsening of original symptoms

This is not an exhaustive list of side effects. For more information regarding the safety of this medicine, please consult the patient information leaflet enclosed with your medication.

This medication is not appropriate for children.

Lamisil 250 mg Tablet cautions

Do not take Lamisil 250 mg tablet if allergic to any of its ingredients including:

  • Terbinafine
  • Magnesium stearate
  • Colloidal anhydrous silica
  • Hydroxypropylmethylcellulose
  • Sodium carboxymethyl starch
  • Microcrystalline cellulose

Do not take Lamisil 250 mg tablet if you have liver disease or another condition of the liver or if you are breastfeeding

Please inform our doctor if you are:

  • Pregnant
  • Have difficulties with your liver or kidneys
  • Have psoriasis
  • Have systemic lupus erythematosus
  • Have a rash as the results of a high level of white blood cells

Tell your doctor if you are taking any medications including over-the-counter products. Specific medical interactions can occur with:

  • Rifampicin prescribed for infections
  • Cimetidine prescribed for gastric conditions
  • Certain antidepressants cush as tricyclic, selective serotonin reuptake inhibitors (SSRI) and monoamine oxidase inhibitors (MAOI)
  • Oral contraceptives
  • Beta-blockers, anti-arrhythmics, propafenone, amiodarone or any medication to treat a heart condition
  • The blood thinner Warfarin
  • Ciclosporin prescribed to prevent rejection after an organ transplant
  • Oral medications prescribed to treat fungal infections such as fluconazole or ketoconazole
  • Medications to treat a cough such as dextromethorphan
  • Caffeine

It is recommended that patients have blood tests before and during treatment to monitor liver function.

Potential serious side effects of Lamisil 250mg tablets include:

  • Jaundice - Yellowing of the eyes or skin
  • Dark urine or pale stool
  • Persistent nausea or other stomach ailments
  • Fatigue
  • Weakness
  • Loss of appetite

This may indicate liver problems. An increase in liver enzymes may be noted in blood tests.

Potentially serious side effects from Lamisil 250mg tablets

  • Difficulty breathing
  • Dizziness
  • Unexplained bleeding or bruising
  • Rash or purplish spots on the skin
  • Stomach pain that radiates to the back - a possible sign of pancreas problems
  • Muscle weakness or pain or dark-brown urine which may indicate muscle breakdown.

Common side effects from Lamisil 250mg tablets include:

  • Headache
  • Stomach ache
  • Diarrhoea
  • Skin discomfort and itching
  • Muscle and joint pain

Uncommon side effects from Lamisil 250mg tablets include:

  • Taste lost or change in taste
  • Changes in mood including depression and anxiety
  • Rare side effects from Lamisil 250mg tablet include:
  • Feeling sick and dizzy
  • Numbness or tingling
  • Hair loss
  • Vertigo
  • Changes in lupus condition
  • Reduction in blood cells

This is not an exhaustive list of side effects. For more information regarding the safety of this medicine, please consult the patient information leaflet enclosed with your medication.

This medication is not appropriate for children.

Do not drive or use heavy machinery when taking Lamisil 250mg tablets if you experience dizziness or a giddy feeling after the initial dose.

Lamisil tablets do not contain lactose or gluten.

Reporting side effects of Lamisil cream or tablets

If you experience any side effects, whether listed above or in the patient information leaflet, consult your doctor or pharmacist for advice. You can find your nearest pharmacy by using the NHS' Find A Pharmacy service.

Always keep medicine out of the sight and reach of children and pets.

Never share your medicine with anybody else, even if they are experiencing the same symptoms as you.

Frequently Asked Questions

What should I do if I miss a dose of Lamisil?

If you miss a dose of Lamisil, take or apply the dose as soon as you remember. Continue to take or apply Lamisil as you normally would. Do not take or apply more Lamisil to make up for the missed dose.

Can I drink alcohol while taking Lamisil?

It is best to avoid alcohol consumption while taking Lamisil 250mg tablets. Alcohol may increase the risk of side effects, such as dizziness or nausea. There should be no problem drinking alcohol while using the cream, however.

What should I do if I accidentally apply more Lamisil 1% cream than I should?

If you accidentally apply more Lamisil cream to your skin, wipe away the excess with a tissue and safely discard of it out of the reach from children and pets.

What should I do if I or someone else accidentally gets the cream in their mouth or eyes?

If the cream gets in your eyes, rinse them immediately under running water. If a small amount gets in your mouth, avoid swallowing and wash your mouth out with clean water. If someone ingests a large amount of the medication, seek immediate medical help.

How long will it take for Lamisil 1% cream to work?

Depending on the type of fungal infection you have, it may take up to two weeks before you begin to notice a difference using Lamisil cream. Typically, patients notice an improvement in their symptoms after two to three days of treatment, though other fungal skin infections, such as ringworm and jock itch, may take up to two weeks before an improvement

Speak to your doctor or a pharmacist if you do not notice an improvement after 2 weeks of treatment with Lamisil cream.

Can I use Lamisil cream alongside other topical treatments?

While treating an infection with Lamisil cream, you should allow several minutes to elapse between applying Lamisil cream to the affected area and any other topical treatment. This allows time for the Lamisil cream to be absorbed by the skin and prevents mixing with ingredients of other products.

Do I need to take all the Lamisil 250mg tablets?

You should complete your course of Lamisil unless your doctor has ordered you to stop. If you experience any side effects which pose a significant danger to your health, stop taking Lamisil and report them to your doctor.

What should I do if I take too many Lamisil 250mg tablets at one time?

If you overdose on Lamisil tablets, seek treatment at the hospital casualty department as soon as possible. Take all medications with you when you go.

How long will it take for Lamisil 250 mg tablets to work?

It can take between six to twelve weeks for Lamisil 250 mg tablets to work.

If you have any concerns about how long it should take before you begin to notice an improvement of your symptoms, speak to your GP or pharmacist.

Can I drive while taking Lamisil 250mg Tablets?

If you experience dizziness while taking Lamisil tablets, you should avoid driving or operating machinery until you feel well enough to do so.

Table of contents

What is Lamisil?

How does Lamisil work?

How do I take Lamisil?

Lamisil side effects and cautions

Frequently asked questions

Treatment information

  • Product Name: Lamisil
  • Manufacturer: GlaxoSmithKline
  • Active Ingredient: Terbinafine hydrochloride
  • Administration: Topical cream or oral tablet
  • Presentation: Smooth, white, glossy cream or Off-white, biconvex, circular tablets
  • Available Strength: 1% cream or 250 mg tablet
  • Exemption: Prescription only medicine
  • Application: Men and women over 18
  • Dosage: Apply cream once to twice daily. Take Lamisil 250 mg tablets as prescribed.
  • Description: Lamisil is an antifungal which is used to treat fungal infections of the skin
  • Drug Class: Antifungal
  • Alcohol Consumption: Do not drink alcohol while using Lamisil
  • When Pregnant: Do not use Lamisil if you are pregnant. Speak to your doctor for further advice.
  • When Breastfeeding: Do not use Lamisil if you are breastfeeding. Speak to your doctor for further advice.
Click here to view the Lamisil - Patient Information Leaflet