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About Product
This content has been written and checked for quality and accuracy by
Mohamed Imran Lakhi Content Administrator GPhC: 2060586 Updated on: 26/05/2020 Next review: 26/11/2020

Buy Loperamide Online

Loperamide, also sold under the brand name Imodium, anti-diarrhoea medication offered as 2 mg hard capsules for the treatment of short-term diarrhoea or diarrhoea associated with irritable bowel syndrome (IBS). The medicine works by slowing the frequency of muscle contractions within the intestine, known as peristalsis.

Before you can buy Loperamide online, you will need to complete a consultation with one of doctors to ensure this treatment is safe for you and your condition. If our doctor deems the treatment suitable, a prescription will be issued to our UK based dispensing pharmacy.

All orders are dispatched in discreet packaging to maintain your privacy. If your order is approved before 3pm on a weekday, our pharmacy will dispatch your order the same day for a guaranteed next-day delivery.

What is diarrhoea?

Diarrhoea is the medical name for loose or watery stools (poo). The symptom can be brought on from a number of conditions including a bacterial or viral infection, anxiousness, food intolerances or underlying health conditions which affect the bowels, such as IBS.

Diarrhoea is caused by excess water in the stools. When food is broken down in the stomach, it enters the intestine where bacteria extract water and nutrients to use in other processes of the body. In order for the bacteria to have a chance of working effectively, the faecal matter must move slowly.

When illnesses or diet causes the faecal matter to pass through the large intestine faster, or if the bacteria are attacked, the body cannot take the water from the faeces as effectively, resulting in diarrhoea.

How does Loperamide work?

Loperamide causes the movement of faecal matter in the intestines to slow down. This increases the time the material stays in the body.

By remaining in the bowel for longer, more water and electrolytes can be absorbed, resulting in a firmer stool.

While the medicine allows more water to be absorbed from faecal matter, it does not promote rehydration. Therefore, it is important to remain hydrated while treating diarrhoea by drinking plenty of water.

How do I take Loperamide?

Follow the instructions provided by the doctor or pharmacist carefully. The dose is based on the type of diarrhoea: acute, short-term or chronic related to ongoing IBS.

For adults with acute diarrhoea:

Two 2 mg capsules for the initial dose and then take one capsule after every loose bowel movement.

For adults with IBS:

Take two 2 mg capsules for the initial dose and one capsule after every loose bowel movement. Continue to take the medication for up to two weeks for an IBS attack.

Take Loperamide capsule with a glass of water and swallow them whole. Do not take more Loperamide than recommended. Do not take more than six capsules in one 24-hour period. This drug in excessive doses is linked to fast or irregular heartbeats.

Contact your doctor if there is no improvement in 48 hours.

Loperamide side effects and cautions

All medicines carry the risk of side effects, though not everybody gets them. Before using Loperamide for the first time, it is important to familiarise yourself with the patient information leaflet (PIL) which comes enclosed with your medication. If you have any concerns about the information in the leaflet, contact your doctor or a pharmacist for advice.


Do not take Loperamide if you are allergic to any of the ingredients listed below:

  • Loperamide hydrochloride
  • Lactose monohydrate
  • Maize Starch
  • Magnesium stearate
  • Gelatin
  • Certain dyes such as Quinoline yellow, Indigo Carmine, Erythrosine, Titanium dioxide, black iron oxide

If you experience any signs of an allergic reaction, stop taking Loperamide and go straight to your nearest A&E department. Take the packaging and any remaining medicine with you.


Speak to your doctor before taking Loperamide if you:

  • are constipated or have a history of severe constipation
  • are dehydrated
  • are diagnosed with liver disease
  • are lactose intolerant
  • are over the age of 40 and have not had an IBS attack for a while
  • are over the age of 40 and this IBS attack is different than others
  • are vomiting or nauseous
  • cannot or have trouble passing urine
  • currently have a fever
  • have an inflamed intestine or an inflammatory bowel disease such as ulcerative colitis or Crohn's disease
  • have travelled abroad recently
  • have unexplained weight loss or loss of appetite
  • see blood in your stool

Do not take Loperamide to treat IBS flair ups unless your doctor has diagnosed you with the disease.

If you have AIDS, stop taking the medication if you notice bloating in your stomach or become constipated.


Tell your doctor if you are taking:

  • Any medication for your stomach
  • Gemfibrozil for high cholesterol and triglycerides
  • Itraconazole for fungal infection
  • Ketoconazole for fungus or yeast infections
  • Quinidine for abnormal heart rhythms or malaria
  • Ritonavir for HIV

Pregnancy and breastfeeding

If you are currently pregnant or considering getting pregnant, do not take Loperamide without talking to your doctor.

Do not take this medication if you are breastfeeding as it can be passed to your infant through breast milk.

Side effects

If experiencing any of the following side effects after taking Loperamide, stop using the medication and seek emergency medical attention:

  • Bowel obstruction (severe constipation, pain, bloating and nauseousness after eating)
  • Erythema multiforme (Blisters with dark spots in the middle like a target)
  • Loss or reduced level of consciousness
  • Megacolon (Widening of the colon with abdominal pain, fever and rapid heart rate)
  • Stevens-Johnson Syndrome (Rash with blisters and skin that peels, usually around the mouth, nose, eyes and genitals)
  • Toxic epidermal necrolysis (Widespread rash with peeling skin)
  • Unable to pass urine

Common side effects of taking Loperamide might include:

  • Constipation
  • Flatulence (Wind)
  • Headache
  • Nausea

Uncommon side effects include:

  • Dizziness
  • Drowsiness
  • Dry mouth
  • Indigestion
  • Rash
  • Stomach discomfort
  • Vomiting and nausea

Rare side effects may include:

  • Bloating
  • Fatigue
  • Itching
  • Narrowing of the pupils
  • Tightening of the muscles

This is not an exhaustive list of side effects. More information regarding the safety of this medicine can be found in the patient information leaflet enclosed with your medicine. Alternatively, you can view the patient information leaflet for Loperamide online here.

Reporting side effects

If you experience any side effects, whether listed above or in the patient information leaflet, speak to your doctor or pharmacist for assistance. You can use the NHS' Find A Pharmacy website to find your nearest pharmacy.

Always keep medicine out of the sight and reach of children and pets.

Never share your medicine with anyone else, even if they have the same symptoms as you.

Frequently Asked Questions

How do I know when to stop taking Loperamide?

Do not take Loperamide longer than two weeks if you have IBS. Stop taking the drug if you see no improvement within 48 hours whether it is for acute or IBS-related diarrh

Stop taking this drug if you have any serious side effects or if your doctor tells you to stop after you report side effects.

What should I do if I miss a dose of Loperamide?

If you forget to take a dose of Loperamide, take it as soon as you remember. If you are close to taking the next dose, skip the missed one. Avoid doubling up on the medication.

Can I drink alcohol while taking Loperamide?

Loperamide can make you drowsy and alcohol might enhance that side effect. Avoid drinking alcohol while on this medication.

What should I do if I take too much Loperamide?

If you take too much Loperamide, go to the hospital casualty department. Too much of this medication can lead to serious heart problems.

Can I take Loperamide with other medications?

Tell your physician if you take any medications including over-the-counter products or herbal supplements.

Can I drive or operate machinery after taking Loperamide?

You may experience drowsiness or dizziness after taking Loperamide. It is better to see how the drug affects you before driving a car or operating machinery.

How should I store Loperamide capsules?

Store the capsules somewhere out of sight and reach of children. Store the bottle in an area that does not get hotter than 25°C. Do not discard unused medication in with your household waste. Talk to the pharmacist to find out how to properly dispose of Loperamide capsules once they expire.

Table of contents

Buy Loperamide Online

How does Loperamide work?

How do I take Loperamide?

Loperamide side effects and cautions

Frequently asked questions

Treatment information

  • Product Name: Loperamide
  • Active Ingredient(s): Loperamide hydrochloride
  • Administration: Oral
  • Presentation: Green and dark grey capsules
  • Available Strength: 2mg
  • Exemption: Pharmacy
  • Application: Men and women over 18+
  • Dosage: Take 2 capsules initially and then take 1 capsule after each loose bowel movement
  • Description: Loperamide is an antidiarrhoeal which regulates bowel movements and thickens faeces
  • Drug Class: Antidiarrhoeal
  • Alcohol Consumption: Do not consume alcohol while taking Loperamide
  • When Pregnant: Tell your doctor if you are pregnant or intend on becoming pregnant before taking Loperamide.
  • When Breastfeeding: Tell your doctor if you are breastfeeding before taking Loperamide.
Click here to view the Loperamide - Patient Information Leaflet

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