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HC45 Cream

In Stock
1% cream
Package Type
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You must complete a short online consultation so that our prescriber can ensure that the treatment is suitable for you.
Order now to receive your order Friday, May 24
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How to order
  1. Click on the green "Back To Get Started" button, then click "Start Consultation" button on the next page.
  2. Fill in our short consultation form.
  3. Choose delivery method and mode of payment.
  4. Our team of expert prescribers will assess whether medication is suitable.
  5. If you get the green light and it is deemed suitable, your order will be processed quickly and efficiently.
Confidential Service

Your privacy is important, Prescription Doctor are committed to keeping your details completely confidential.

This is why we also take steps to conceal your prescription products under two layers of packaging.

Delivery and Packing
Discreet Delivery?

We have a commitment to delivering a discreet service and understand your need for privacy. We ship all orders via a trackable courier using discreet, plain packaging.

Do I Need to Wait in All Day for Delivery?

Once your order is dispatched you will receive a tracking number via sms and email.

Do You Deliver on Weekends?

We deliver medications between Monday and Saturday. You can upgrade to Saturday delivery on Friday.

My Order Hasn’t Arrived What Should I Do?

You should receive a tracking number with your order which you can use this number to track your parcel online. This should give you a clear indication of where your parcel is. If you haven’t received your parcel in the time frame given by our couriers, contact your local depot to find out where it is. You can also contact our support team who will do this for you.

Can I Be Notified by Text?

On checkout you will be asked to leave your mobile number so our courier can text you about the delivery. This is also useful if the courier has problems finding your address. We will not use your mobile number for anything else.

Payment Methods
How Can I Pay for My Order?

You can pay for your order using credit, debit card or via bank transfer.

I Don’t Have a Credit Card, How Can I Pay?

If you don’t have a credit or debit card you can pay via bank transfer. We will give you a unique reference number at checkout along with details of how to make the transfer. Once the money has cleared in our account, we will process your order.

How Do You Keep My Details Safe?

We are a completely secure site and take many measures to ensure your details are kept safe. We understand that you have a right to extreme privacy when purchasing sensitive health medications. All information that you provide to us is stored on our secure servers. Any payment transactions will be encrypted using SSL technology.

Payment and refunds?

You can pay for your order using credit, debit card and bank transfer.

Card Payment: Please notify us that you wish to cancel your order. Your refund will show available In 1 - 3 days.

Bank Transfer: A member of our team will contact you requesting for your bank details. These details are only used to transfer the funds back into your account.

Treatment Information

Table of contents

Patient Reviews: How HC45 Cream Has Made a Difference

Buy HC45 Hydrocortisone Cream Online

HC45 Hydrocortisone Cream is clinically proven to effectively reduce the body's inflammatory response.

It can be used to treat inflammatory skin conditions such as:

  • contact or allergic dermatitis
  • mild to moderate eczema
  • insect bite reactions
  • allergic reactions to nickel, plants or detergents

HC45 Cream is available to order from our online pharmacy. Simply fill out or short medical questionnaire to begin your order. Our medical team will review your questionnaire and determine whether the cream is safe for you to take.

Our UK-based pharmacy can dispatch your item the same day if it is approved by our medical team before 3pm, Monday to Friday. We package all items in plain packaging to ensure your privacy.

How Does HC45 Hydrocortisone Cream Work?

When an allergen or irritant causes the immune system to release histamine, the inflammation of the blood vessels causes the skin to become red, itchy and painful.

HC45 Hydrocortisone Cream contains a corticosteroid called hydrocortisone. This mild steroid reduces itching, redness, irritation and inflammation for up to 12 hours.

The cream also moisturises the skin, and encourages healing.

How long does HC45 Cream take to work?

It may take between 3 and 7 days of using HC45 Cream to relieve your symptoms. If your symptoms do not improve, or indeed become worse after these 7 days, stop using HC45 Cream and speak to a doctor or a pharmacist.

How Do I Use HC45 Hydrocortisone Cream?

HC45 Hydrocortisone Cream is a smooth white cream that can be applied directly and sparingly to the inflamed areas of the skin once or twice a day.

Use a small amount and rub it gently into the affected area.

HC45 Hydrocortisone Cream should not be used for longer than 7 consecutive days. If there is no improvement to the skin after 7 days, stop using HC45 Cream and consult your doctor or pharmacist.

Do not apply HC45 Cream to broken or infected skin.

Always wash your hands after using HC45 Cream.

HC45 Cream Side Effects & Cautions

Read the packaging and the enclosed patient information leaflet carefully before using HC45 cream.

You can view the patient information leaflet for HC45 Cream online.

If you have any questions about any of the information presented in the patient information leaflet, feel free to message one of our online prescribers using the "my chats" feature of your Prescription Doctor account.

Who should not use HC45 Cream?

HC45 Cream is not suitable for everyone.

Do not use this cream to treat:

If you are unsure whether HC45 Cream is suitable for you, ask one of our online prescribers during your online consultation.

Side effects

All medicines carry the risk of side effect. However, just because a side effect is listed, it doesn't guarantee that you will experience it.

Despite this, you must remain vigilant to all potential side effects while using HC45 Cream.

Side effects may include:

  • Localised skin reactions
  • Blurred vision
  • Thinning of the skin

This is not a complete list of side effects associated with HC45 Cream. For a complete list of side effects, read the patient information leaflet enclosed with your medicine.

If you experience any side effects to HC45 Cream, even if they are not listed above or in the patient information leaflet, inform a doctor or a pharmacist.

You can discuss any side effects you experience with one of our online doctors using the "my chats" feature of your Prescription Doctor account.


Do not use HC45 Cream if you are allergic to hydrocortisone or any of its other ingredients, including:

  • cetomacrogol
  • cetostearyl alcohol
  • emulsifying wax
  • liquid paraffin
  • phenoxyethanol
  • purified water
  • white soft paraffin

If you experience an allergic reaction after using HC45 Cream:

  • stop using the product immediately
  • speak to your doctor.

For severe allergic reactions, seek medical attention right away. Go straight to your nearest accident and emergency department. Remember to take the packaging and any remaining treatment with you, so that doctors treating you know exactly what and how much you took.

Can I use HC45 Hydrocortisone Cream while pregnant or breastfeeding?

Do not use HC45 Cream if you are pregnant, planning a pregnancy, or breastfeeding, unless you have been told to do so by your doctor.

Other safety information

Let our online prescribers know whether you are using any other medicines. This includes medicines bought over the counter, or prescribed by your doctor.

Warning: HC45 Cream contains liquid paraffin, which is highly flammable. Avoid naked flames while using HC45 Cream. To prevent the risk of fires, wash all surfaces that come into contact with the cream regularly, including clothing and bedding.

Do not use HC45 Cream past the expiry date printed on the packaging.

Always store HC45 Hydrocortisone Cream out of sight and reach from children and pets. Store HC45 Cream below 25°C.

Never share your HC45 Cream with anybody else - even if they are experiencing the same symptoms or have been diagnosed with the same condition as you.

Frequently Asked Questions

What should I do if I forget to take HC45 Hydrocortisone Cream when I should?

If you forget to use HC45 Hydrocortisone Cream, apply it as soon as you remember to. Do not use more HC45 Cream to make up for the missed dose.

If you regularly forget to apply the cream, you may want to set yourself an alarm to help you remember.

What should I do if I take too much HC45 Hydrocortisone Cream?

If you accidentally use too much HC45 Cream, wipe away the excess with a clean tissue and throw it away.

Can I drink alcohol while taking HC45 Hydrocortisone Cream?

Yes, you can drink while using HC45 Hydrocortisone Cream. Avoid drinking more than 14 units of alcohol a week, as per the government's recommendation.

Will HC45 Hydrocortisone Cream impact my ability to drive or operate machinery?

No, using HC45 Hydrocortisone Cream should not impact your ability to drive or operate heavy machinery.

Can I use HC45 Hydrocortisone Cream on my face?

No, you should not use HC45 Cream on your face. You should also avoid using it on your anus or genitals, on broken or infected skin, or on cold sores, acne or athlete's foot.

Where should I store HC45 Hydrocortisone Cream?

HC45 Hydrocortisone Cream should be stored out of the reach of children and away from direct sunlight. Do not continue to use HC45 Hydrocortisone Cream past the expiry date.

Can I continue to take other medications alongside HC45 Hydrocortisone Cream?

HC45 Hydrocortisone Cream is not known to react or interact with any other medications. However, you should discuss this with your doctor.

If you use an emollient or moisturiser to treat your skin condition, apply that first and wait for 30 minutes before applying HC45 Hydrocortisone Cream.


Reckitt Benckiser Healthcare (UK) Ltd, 2020. Summary of Product Characteristics: Hc45 Hydrocortisone Cream.

Treatment information

  • Product Name: HC45 Hydrocortisone Cream
  • Manufacturer: Reckitt Benckiser Healthcare Ltd
  • Active Ingredient(s): Hydrocortisone Acetate
  • Administration: Topical
  • Presentation: Cream
  • Available Strength: 1% w/w
  • Exemption: Pharmacy
  • Dosage: Apply a small amount once or twice a day for up to 7 days.
  • Description: HC45 is a steroid cream that helps to reduce inflammation and irritation of the skin.
  • Drug Class: Corticosteroid
  • Alcohol Consumption: No influence
  • When Pregnant: Speak to a doctor before using HC45 Cream during pregnancy.
  • When Breastfeeding: Speak to a doctor before using HC45 Cream if you are breastfeeding.
  • Price: 3.99 GBP
Click here to view the HC45 Cream - Patient Information Leaflet

Authored & Reviewed By

Adil Bhaloda

Adil Bhaloda

Adil provides governance for the online services, overseeing prescription dispensation in line with UK pharmacy standards.

Published on: 10/03/2022 Reviewed on: 13/03/2024

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