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How Long Does Vitaros Cream Take To Work?

This article looks at Vitaros Cream efficacy, timing, duration, long-term use, and what could affect how well it works. So, if you’re wondering how quickly can Vitaros Cream help treat erectile dysfunction? you’re in the right place.

Speed of Action

Vitaros cream is used to treat erectile dysfunction (ED). It should be applied into the opening at the tip of your penis.

Vitaros cream works within 5 to 30 minutes after application.

Vitaros cream absorption time is between 5 and 30 minutes, so you may want to wait 30 minutes before having sex.

Vitaros cream can take as little as 5 minutes to cause an erection.

Treatment Duration

Vitaros cream only needs to be taken when you want to have sex.

Vitaros cream half-life is around 1 to 2 hours after application. It can remain effective for up to 2 hours.

You should only use Vitaros cream if you’ve been diagnosed with ED. It should not be used by:

  • anyone under the age of 18
  • women, especially if pregnant or breastfeeding

Long-term Use

You can use this medication while you’re getting treated for ED, but it may not be a long-term solution. You and your doctor can discuss your dosage and long-term use of Vitaros cream.

You can use Vitaros cream for as long as you need it, but if you or your partner get bothersome side effects, you may need to stop treatment.

Vitaros cream shouldn’t be used more than once in 24 hours and only 2 to 3 times a week.

Risks and Benefits of Long-term Use

It’s important to have regular medical check-ups when using Vitaros (alprostadil) cream.

The risks of using Vitaros cream long-term include:

  • increased chance of side effects, such as irritations to your and your partner’s genitalia and fainting
  • painful, prolonged erections

The benefits of using Vitaros cream long-term include:

  • being able to get an erection and have sex
  • improved confidence
  • works quickly
  • an alternative to tablets, if you cannot take them

Dosage and Factors Affecting Efficacy

You should urinate before using Vitaros cream. If you urinate too soon after application, this may affect its efficacy.

Vitaros cream is available in 2 doses - 200/300 mcg in 100 mg. Your doctor will try you on the lowest dose first.

What to Do If You Find the Dose Ineffective

If you find your Vitaros cream dose ineffective after several tries, speak to a doctor or prescriber. They may recommend a different ED treatment, or increase your dose if you’re on the lower dose.


Vitaros Cream works in around 5 to 30 minutes and lasts 1 to 2 hours. Being sexually stimulated will make it more effective. Speak to a doctor or prescriber if you need additional guidance about the long-term use of Vitaros cream.

We also have a range of treatments available, as well as additional resources and support regarding the use of Vitaros cream for ED.

Authored By

Hannah Aitken

Medical Content Writer
Hannah is a medical content writer who utilises her nursing expertise alongside her passion for writing healthcare content.

Published on: 06/11/2023

Reviewed By

Dr. Giuseppe utilises his extensive experience in general practice to ensure the accuracy and safety of the website's content.

Reviewed on: 16/11/2023
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