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PLEASE NOTE: This treatment is not available through our online pharmacy service. This page is for information only. If you are experiencing any of the symptoms related to the condition(s) this medication treats, we strongly recommend that you see your GP in person.


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How to order
  1. Click on the green "Back To Get Started" button, then click "Start Consultation" button on the next page.
  2. Fill in our short consultation form.
  3. Choose delivery method and mode of payment.
  4. Our team of expert prescribers will assess whether medication is suitable.
  5. If you get the green light and it is deemed suitable, your order will be processed quickly and efficiently.
Confidential Service

Your privacy is important, Prescription Doctor are committed to keeping your details completely confidential.

This is why we also take steps to conceal your prescription products under two layers of packaging.

Delivery and Packing
Discreet Delivery?

We have a commitment to delivering a discreet service and understand your need for privacy. We ship all orders via a trackable courier using discreet, plain packaging.

Do I Need to Wait in All Day for Delivery?

Once your order is dispatched you will receive a tracking number via sms and email.

Do You Deliver on Weekends?

We deliver medications between Monday and Saturday. You can upgrade to Saturday delivery on Friday.

My Order Hasn’t Arrived What Should I Do?

You should receive a tracking number with your order which you can use this number to track your parcel online. This should give you a clear indication of where your parcel is. If you haven’t received your parcel in the time frame given by our couriers, contact your local depot to find out where it is. You can also contact our support team who will do this for you.

Can I Be Notified by Text?

On checkout you will be asked to leave your mobile number so our courier can text you about the delivery. This is also useful if the courier has problems finding your address. We will not use your mobile number for anything else.

Payment Methods
How Can I Pay for My Order?

You can pay for your order using credit, debit card or via bank transfer.

I Don’t Have a Credit Card, How Can I Pay?

If you don’t have a credit or debit card you can pay via bank transfer. We will give you a unique reference number at checkout along with details of how to make the transfer. Once the money has cleared in our account, we will process your order.

How Do You Keep My Details Safe?

We are a completely secure site and take many measures to ensure your details are kept safe. We understand that you have a right to extreme privacy when purchasing sensitive health medications. All information that you provide to us is stored on our secure servers. Any payment transactions will be encrypted using SSL technology.

Payment and refunds?

You can pay for your order using credit, debit card and bank transfer.

Card Payment: Please notify us that you wish to cancel your order. Your refund will show available In 1 - 3 days.

Bank Transfer: A member of our team will contact you requesting for your bank details. These details are only used to transfer the funds back into your account.

Treatment Information

Table of contents

What Is Istin?

Istin is a medicine used to lower blood pressure. The active ingredient of Istin is amlodipine, and the medicine is available in strengths of 5mg or 10mg tablets.

You can buy Istin for high blood pressure online from Prescription Doctor. Simply complete our online consultation with our registered prescriber. If your order is approved by our doctor before 3pm, our UK registered pharmacy will dispense and dispatch your medicine the same day, and post it out using a discreet next-day delivery.

What Is High Blood Pressure?

High blood pressure is when blood is pumped around the body with too much force. This can be due to the heart beating too hard or fast, your blood vessels being narrowed by contracting muscles or a build up of plaque, or a combination of both an increased heart rate and constricting blood vessels.

In most cases, high blood pressure does not cause symptoms, so it’s unlikely you will know that you have it.

The only reliable way to know if you have high blood pressure is to get your blood pressure checked by your doctor. Some pharmacies may offer a blood pressure check if you can’t get to your doctors. You can also buy home blood pressure monitors from some pharmacies or online.

Why is it important to treat high blood pressure?

If left untreated, high blood pressure can damage the blood vessels, and increase your risk of cardiovascular conditions, such as heart attack or stroke.

Treating high blood pressure can help relieve strain on your body and decrease your risk of complications.

How Does Istin Work?

Istin contains amlodipine, which is a calcium channel blocker.

A calcium channel blocker causes the muscle cells in the artery walls to relax.

When this happens, the arteries widen and blood can pass through more easily – the heart does not have to work so hard to ensure enough oxygen is pumped around the body, and therefore the blood pressure is lowered to a safer level.

How Do I Take Istin?

Istin is only available on prescription, and therefore your doctor should be able to explain to you how to take it. It’s important to take Istin exactly ask your doctor has prescribed.

Usually, Istin will be taken once a day. You can choose any time to take your medication, although it is best to take it at the same time each day.

The dose will usually start at 5mg and be changed to 10mg if needed.

You can take Istin with or without food. Istin tablets should be swallowed whole with a glass of water.

If you find pills difficult to swallow, Istin can be dissolved in water – if you choose this option, you should drink the mixture immediately.

Do not eat or drink any products that include grapefruit as this will react negatively with Istin (amlodipine).

What should I do if I forget to take Istin when I should?

If you realise you have missed a dose of Istin you should take it once you remember to. However, if it is almost time for your next dose, skip the missed dose and continue to take Istin as prescribed.

Do not take more Istin to make up for the dose you missed.

What should I do if I take too much Istin?

If you do take too much Istin, you should contact your doctor or go straight to the nearest hospital A&E.

Do not drive; if you have no one to drive you, you must call an ambulance. An overdose of Istin can cause dizziness and tiredness, and therefore driving is dangerous. When you go to hospital, take the packaging including the patient information leaflet for the medication as well as any remaining medication with you.

Istin Side Effects and Cautions

Before taking Istin, it’s important to familiarise yourself with the information outlined in the patient information leaflet enclosed with your medicine. The patient information leaflet contains important information regarding the safety of Istin, including instructions on how to take and store the medicine.

View the patient information leaflet for Istin 5 mg and 10 mg online.

If you are unsure about any information printed in the patient information leaflet, speak to your doctor or a pharmacist for advice.

Who Should Not Take Istin?

Istin can be an effective medication for high blood pressure, but it is not suitable for everyone. Your doctor will only prescribe it if they feel it is suitable for you. Those who should not take Istin include:

  • Those who have an allergy to any of the ingredients of Istin
  • Women who are pregnant (or trying to conceive) or breastfeeding
  • Anyone with kidney disease or liver disease
  • Anyone with heart failure
  • Anyone who has had a heart attack within the last month

Who Should Get Medical Advice Before Using Istin?

Istin can be taken by some people who also require medical advice beforehand to ensure it is the correct medication. They may need a lower dose or additional tests and checks. These people include:

  • The elderly since dizzy spells (a potential side effect of Istin) can cause more damage
  • Anyone with liver issues
  • Those with heart failure

Side effects of Istin

All medicines carry the risk of side effects, though not everybody who takes Istin will experience them.

Very common and common Istin side effects include:

  • Abdominal pain
  • Diarrhoea, constipation or indigestion
  • Dizziness
  • Headaches
  • Muscle cramps
  • Nausea (feeling sick)
  • Oedema (fluid retention)
  • Sleepiness
  • Swelling of the ankles
  • Tiredness
  • Visual disturbances
  • Weakness

This is not an exhaustive list of side effects. Further information regarding the safety of Istin, including a complete list of side effects, can be found within the patient information leaflet enclosed with your medicine.

If you experience any side effects while taking Istin, regardless of whether they are listed above or in the patient information leaflet, speak to your doctor or ask a pharmacist for help.


Do not take Istin if you are allergic to amlodipine or any of the medicine’s other ingredients listed in the patient information leaflet.

If you experience the signs and symptoms of an allergic reaction, stop taking Istin and seek immediate medical attention. Go straight to the accident and emergency department of your nearest hospital. Remember to take the packaging and any remaining medicine with you so that doctors treating you know exactly what you have taken.

Signs of an allergic reaction may include:

  • Chest tightening
  • Dry, red and cracked skin
  • Itchy, red watery eyes
  • Raised, itchy, red rash (hives)
  • Swelling of the lips, tongue, eyes or face
  • Tummy pain, nausea, vomiting or diarrhoea
  • Wheezing

Pregnancy and breastfeeding

If you are pregnant, plan on becoming pregnant or breastfeeding, speak to your doctor before taking Istin.

The safety of Istin during pregnancy has not been established.

Small amounts of amlodipine can pass through breast milk.

Can I Take Istin With Other Medications?

It is vital that you let your doctor know about any other medication you are taking (including herbal medication) when being prescribed Istin UK as some combinations of medication can have adverse effects. These include:

  • St John’s wort (hypericum perforatum)
  • Any other medication that causes lower blood pressure
  • Oestrogens such as the contraceptive pill
  • Corticosteroids

Other safety information

Please inform our prescriber of all medicines you are currently taking, including those prescribed by your doctor, or bought over the counter, as well as any health or herbal supplements you may be taking.

Do not take Istin past the expiry date printed on the packaging. The date refers to the last day of the specified month.

Never throw away medicine via household or water waste as it can be detrimental on the environment. You can ask your local pharmacy to dispose of unwanted or expired medicine on your behalf.

Always store Istin and other medicines out of sight and reach from children and pets.

Never share your medicine with anybody else, even if they are experiencing the same symptoms or have been diagnosed with the same condition as you.

Frequently asked questions

How long does Istin take to work?

Istin starts to work from the day you begin taking it, though it can take several weeks for the medicine to reach its peak effectiveness. It is important to continue to take Istin as prescribed, even if you do not notice any difference in how you feel.

How long should I take Istin for?

Istin is usually taken for the rest of your life to keep your blood pressure low.

How do I stop taking Istin?

If you wish to stop taking Istin, it’s important to speak to your doctor first. They will be able to discuss why you wish to stop taking the medicine and suggest a suitable substitute for you.

What happens if I stop taking Istin?

If you stop taking Istin, it is likely your blood pressure will return to the level prior to treatment. It is important that blood pressure is kept under control to prevent complications from occurring.

Can I drink alcohol while taking Istin?

You can drink alcohol while taking Istin. However, this might affect how Istin work’s, and your blood pressure might lower too much causing dizziness, tiredness, and headaches. If this happens, stop drinking alcohol but continue to take Istin as directed.

Will Istin impact my ability to drive or operate machinery?

Although for the majority of the time Istin will not affect your ability to drive or operate machinery, if you feel dizzy or sleepy when taking it, you should not do either of these activities.

Where Can I Buy Istin Online?

After receiving advice from your doctor, you can buy Istin online from Prescription Doctor.

To begin your order, complete our online medical questionnaire for one of our doctors to review. If the treatment is deemed suitable for you, a prescription will be issued for our pharmacy to dispense.

All items are dispatched straight to your door via a fast and discreet next-day delivery.

Table of contents

What Is Istin?

What Is High Blood Pressure?

How Does Istin Work?

How Do I Take Istin?

Istin Side Effects and Cautions

Frequently Asked Questions

Where Can I Buy Istin Online?


NHS, 2019. High Blood Pressure

NHS, 2018. Amlodipine

Pfizer, 2020. Istin 5 mg Tablets: Summary of Product Characteristics

Treatment information

  • Product Name: Istin
  • Manufacturer: Pfizer
  • Active Ingredient(s): Amlodipine
  • Administration: Oral
  • Presentation: Tablets
  • Available Strength: 5 mg, 10 mg
  • Exemption: Prescription-only
  • Dosage: Take as prescribed
  • Description: Istin is a brand of amlodipine, used to treat high blood pressure
  • Drug Class: Calcium channel blocker
  • Alcohol Consumption: Limit alcohol consumption while taking Istin
  • When Pregnant: Speak to your doctor before taking Istin if you are pregnant or planning a pregnancy
  • When Breastfeeding: Speak to your doctor before taking Istin if you are breastfeeding
  • Related Drug: Amlodipine
Click here to view the Istin - Patient Information Leaflet

Authored & Reviewed By

Adil Bhaloda

Adil Bhaloda

Adil provides governance for the online services, overseeing prescription dispensation in line with UK pharmacy standards.

Published on: 23/02/2021 Reviewed on: 13/03/2024

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