Your privacy is important, Prescription Doctor are committed to keeping your details completely confidential.
This is why we also take steps to conceal your prescription products under two layers of packaging.
We have a commitment to delivering a discreet service and understand your need for privacy. We ship all orders via a trackable courier using discreet, plain packaging.
Once your order is dispatched you will receive a tracking number via sms and email.
We deliver medications between Monday and Saturday. You can upgrade to Saturday delivery on Friday.
You should receive a tracking number with your order which you can use this number to track your parcel online. This should give you a clear indication of where your parcel is. If you haven’t received your parcel in the time frame given by our couriers, contact your local depot to find out where it is. You can also contact our support team who will do this for you.
On checkout you will be asked to leave your mobile number so our courier can text you about the delivery. This is also useful if the courier has problems finding your address. We will not use your mobile number for anything else.
You can pay for your order using credit, debit card or via bank transfer.
If you don’t have a credit or debit card you can pay via bank transfer. We will give you a unique reference number at checkout along with details of how to make the transfer. Once the money has cleared in our account, we will process your order.
We are a completely secure site and take many measures to ensure your details are kept safe. We understand that you have a right to extreme privacy when purchasing sensitive health medications. All information that you provide to us is stored on our secure servers. Any payment transactions will be encrypted using SSL technology.
You can pay for your order using credit, debit card and bank transfer.
Card Payment: Please notify us that you wish to cancel your order. Your refund will show available In 1 - 3 days.
Bank Transfer: A member of our team will contact you requesting for your bank details. These details are only used to transfer the funds back into your account.
Nytol is a sleep aid which contains a sedating antihistamine called diphenhydramine hydrochloride. It is used to treat temporary insomnia in adults. Nytol helps people fall asleep faster and sleep better. With a good night's sleep, you can wake up feeling well-rested and refreshed.
Nytol Original is available as a 25mg tablet or a 50mg tablet (Nytol One a Night). Nytol Herbal is another version of the treatment, which contains natural ingredients such as valerian root.
Insomnia is a condition which has become more common in recent years. The NHS states that feelings of stress and anxiety can make it difficult to fall asleep or cause you to wake up in the night and struggle to get back to sleep. Illness, pain, and allergies can also make it difficult to find a comfortable position and fall asleep.
While conditions like stress, anxiety, pain and allergies are usually temporary, they can affect your sleep for a short while. In turn, disrupted sleep can harm how you feel the following day.
Nytol works through its active ingredient, diphenhydramine, which is an antihistamine.
The primary effect of an antihistamine is to target histamine, a naturally occurring chemical in the body that is released during an allergic reaction. Its secondary, and in many cases unwanted, effect is to cause drowsiness. However, Nytol uses this side effect to its advantage, entering the brain in large quantities and making you feel drowsy enough for a good night's sleep.
On average, you will begin to feel drowsy around 20-30 minutes after taking Nytol. This effect lasts 4-6 hours before wearing off, by which time you should already be asleep.
Clinical trials have shown Nytol's active ingredient to be effective against insomnia. One study compared 50 mg of diphenhydramine (the same as in two Nytol Original tablets or one Nytol One-A-Night tablet) against a placebo in 111 patients with mild to moderate insomnia. Patients generally preferred diphenhydramine, reporting less time to fall asleep and feeling more rested in the morning.
A separate trial also tested 25 mg diphenhydramine in insomniac patients and found a significant improvement in sleep efficiency compared with a placebo.
Take Nytol Original by swallowing two tablets with water 20 minutes before bedtime. For Nytol One a Night, take one tablet instead. Two tablets of Nytol Original contain the same amount of diphenhydramine as one tablet of Nytol One a Night.
If you wake up in the middle of the night, do not take any tablets in an attempt to get back to sleep. Do not take either form of Nytol for more than two weeks straight without first consulting your clinician.
You must know exactly how to take Nytol to do so safely. Taking too much medication can result in adverse side effects.
Nytol Original's dosage is two tablets per night. Each tablet contains 25mg of diphenhydramine.
Nytol One a Night's dosage is one tablet per night. Each tablet contains 50mg of diphenhydramine, the equivalent of two Nytol Original tablets.
If you forget to take a dose of Nytol, skip that night's administration and take it as usual the next night. Never take two doses at once to make up for a missed one.
If you have taken too much Nytol, contact a doctor or your nearest hospital. Do not take more than the recommended dose of Nytol in one night, even if you wake up and cannot get back to sleep.
Like any medication, Nytol Original and Nytol One a Night may cause unwanted side effects. It is important to know what could occur before starting a treatment, so that you can be prepared if they occur.
Common (may affect up to 1 in 10 people) | Frequency Unknown |
|---|---|
|
|
If you experience any side effects while on either Nytol treatment, report them to your clinician or to the government's Yellow Card Scheme. Doing so helps further narrow down how often these effects occur. For a full list of potential side effects, see the Patient Information Leaflets for the medicines.
Nytol may result in serious side effects. If any of the following occur, stop taking the medicine and contact your doctor immediately:
Not everyone will be eligible for Nytol. You cannot take either form of Nytol if you:
Some factors may affect your eligibility to use Nytol, but will not necessarily rule out your chance to take it. Speak to your clinician if you have:
If your sleeping difficulties persist, talk to your clinician. Nytol may become less effective if you use it continuously.
Nytol may interact negatively with other medications. Speak to your clinician before starting Nytol if you are taking:
Avoid other antihistamines while taking Nytol.
If you are pregnant, may be pregnant, planning to become pregnant, or breastfeeding, talk to your clinician before starting Nytol. It may affect your eligibility to use this medication.
No, you cannot take two Nytol One-A-Night tablets. This would result in 100mg of diphenhydramine being in your body, which is a potentially dangerous amount. Take One-A-Night once a night.
Nytol Original contains 25mg of diphenhydramine, while Nytol One-A-Night contains 50mg. This is essentially the only difference between the two products. Because Nytol Original is two tablets and Nytol One-A-Night is one, both medications deliver the same amount of diphenhydramine into your body.
Nytol Original contains the antihistamine diphenhydramine, whereas Nytol Herbal contains natural herbal remedies. Original is for short-term relief and should not be used for more than two weeks without a clinician's approval, whereas Herbal can be used longer and should be taken consistently for a period before its full effects set in.
If unsure which treatment suits you best, consult your clinician.
Nytol has the potential to become addictive if taken for extended periods, though it is unlikely. That is why you shouldn't take it for longer than two weeks without first confirming with your clinician. You should also speak with your clinician if you have any concerns about addiction involving Nytol.
No, you should not take Nytol if you wake up in the middle of the night. Doing so will mean the medication will still be active in your system when you get up, potentially leaving you dizzy, foggy, and drowsy the next morning. This is especially dangerous if you need to drive or operate machinery.
If you have already taken the treatment before bed, having it again during the night could lead to an accidental overdose and potentially severe side effects.
No, do not drive or operate machinery while on Nytol. Nytol can make you feel drowsy, dizzy, clumsy, or give you blurred vision or an inability to concentrate during the day. This is more likely when you first start treatment. If in doubt, contact your clinician.
Do not drink alcohol while taking Nytol. Alcohol can result in a deep sleep, and so if combined with Nytol, you may sleep so deeply that you have difficulty breathing and waking up.
It is possible to take multiple antihistamines at once, under your clinician's advice and guidance, depending on your symptoms. However, you cannot take a secondary drowsy antihistamine alongside Nytol, as the drowsiness effect will be too strong. Other non-drowsy antihistamines may be appropriate.
Nytol can generally be taken alongside painkillers like paracetamol and ibuprofen. It is worth noting that painkillers containing codeine can make the user feel drowsy, so the effect of Nytol may become too strong if taken in conjunction with one. Speak to your clinician first.
Yes, you can buy both forms of Nytol from online sources like Prescription Doctor. We deliver straight to your door with the potential for next-day delivery, if your order is processed before 3pm on a weekday. It will be dispatched from our GPhC-registered pharmacy.
Keep Nytol Original and Nytol One-A-Night out of the sight and reach of children. Do not use the medication if the printed expiry date has passed. Store the tablets in a dry place.
If disposing of expired/unwanted medication, do not throw any tablets away via household waste or wastewater. Ask your clinician how best to dispose of them.
© 2013 - 2026 Al Muhsineen Limited. All Rights Reserved. Registered Pharmacy: 34 Halliwell Road, Bolton BL1 8RL. Registered Office: 254 First Floor, Shearbrow, Blackburn, England, BB1 8DS
