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Nytol Original
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You can pay for your order using credit, debit card and bank transfer.
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Treatment Information
![Mohamed Imran Lakhi]()
Table of contents
Patient Reviews: How Nytol Original Has Made a Difference
What is Nytol?
Nytol is a sleep aid which contains a sedating antihistamine called diphenhydramine hydrochloride. It is used to treat temporary insomnia in adults.
Insomnia is a condition which has become more common in recent years. Feelings of stress and anxiety can make it difficult to fall to sleep, or cause you to wake up in the night and struggle to get back to sleep. Illness, pain and allergies can also make it difficult to find a comfortable position and get to sleep.
While conditions like stress, anxiety, pain and allergies are usually temporary, they can affect your sleep for a short while. In turn, disrupted sleep can harm how you feel the following day.
Nytol helps people to fall asleep faster and have higher quality sleep. With a good night's sleep, you can wake up feeling well rested and refreshed.
Nytol is available as 25mg tablets. The typical dose of Nytol is 2 tablets (50mg) 20 minutes before bed.
You should not use Nytol continuously for longer than 2 weeks without first consulting a doctor.
How does Nytol work?
Nytol contains diphenhydramine - a sedating antihistamine.
Antihistamines are commonly used to treat symptoms of allergies, such as sneezing, runny nose, itching and watery eyes. They work by blocking histamines in the body, which are released as part of the immune response to allergens, such as pollen or pet dander.
Antihistamines are usually split into two groups; non-sedating (non-drowsy) and sedating. They may also be referred to as first generation and second generation antihistamines.
Newer, second generation antihistamines, such as fexofenadine and cetirizine, are less likely to cause drowsiness.
First generation antihistamines, such as diphenhydramine, commonly cause drowsiness. For this reason, first generation antihistamines are preferred by those whose allergy symptoms disrupt their sleep.
It is the sedative effect of diphenhydramine which makes it effective for insomnia. When taken before bed, it helps you fall into a deep sleep quickly.
How to take Nytol?
Take 2 Nytol tablets 20 minutes before bed. Swallow the tablets whole with a glass of water.
Do not crush or chew the tablets.
If you have difficulty swallowing tablets, speak to a pharmacist - Nytol is also available as a liquid.
Do not take more than the recommended dose of Nytol.
Do not take more Nytol if you wake up during the night.
Do not take Nytol for longer than 2 weeks.
Avoid drinking caffeinated beverages (coffee and cola) up to 4 hours before bedtime.
If Nytol is ineffective, or you do not notice an improvement during the 2 weeks of Nytol, inform your doctor.
Side effects and cautions
Before taking Nytol - or any medication for that matter - it is important to familiarise yourself with the safety information contained in the patient information leaflet enclosed with your treatment. You should retain this leaflet inside the packaging and store it in a safe place in case you need to read it again.
Who should not take Nytol?
Nytol is not suitable for everybody.
Do not take Nytol if you:
- Are under 16 years of age
- Have asthma
- Are pregnant
- Are breastfeeding
- Have closed angle glaucoma
- Have a stenosing peptic ulcer
- Have an enlarged prostate gland (prostatic hypertrophy)
- Have an obstruction where the stomach joins the intestines (pyloduodenal obstruction)
- Have a bladder neck obstruction
If you are unsure whether Nytol is safe for you to take, speak to your doctor or a pharmacist.
What other medicines are affected by Nytol?
Nytol may interfere with other medications you are taking. Before you buy Nytol online from us, it's important to inform our medical team of all other medications you are currently taking.
The sedative effect of Nytol may be greater if taken with:
- Alcohol
- Antipsychotics (haloperidol)
- Barbiturates (phenobarbital, amobarbital)
- Benzodiazepines (diazepam, temazepam)
- Other sedating antihistamines (chlorphenamine)
- Sleeping tablets (zopiclone)
- Opioid pain relief (codeine, dihydrocodeine)
- Tricyclic antidepressants (amitriptyline)
If you are unsure whether Nytol will interfere with another medicine you are currently taking, speak to your doctor or pharmacist for advice.
What are the side effects of Nytol?
All medicines carry the risk of causing side effects, though not everybody experiences them. It's important to remain observant of side effects while taking Nytol.
Common side effects (may affect up to 1 in 10 people):
- Dizziness
- Drowsiness
- Dry mouth
- Reduced attention
- Tiredness
- Unsteadiness
This is not an exhaustive list of side effects. Further information regarding the safety of Nytol, including a complete list of side effects, can be found within the leaflet supplied with your medicine.
If you experience any side effects, regardless of whether they are listed above or in the supplied leaflet, inform your doctor or ask a pharmacist for assistance. You can also call the NHS non-emergency helpline on 111.
Allergic reaction to Nytol
Do not take Nytol if you are allergic to or previously experienced an allergic reaction to diphenhydramine.
Nytol contains lactose. Speak to your doctor before taking Nytol if you have been told that you have an intolerance to some sugars.
If you experience an allergic reaction, stop taking Nytol and seek immediate medical attention. Go straight to your nearest accident and emergency department. Do not drive yourself - ask someone to drive you there. Remember to take the packaging and any remaining medicine with you so that doctors know exactly what and how much you have taken.
Signs of an allergic reaction include:
- Chest tightening
- Dry, red and cracked skin
- Itchy, red watery eyes
- Raised, itchy, red rash (hives)
- Swelling of the lips, tongue, eyes or face
- Tummy pain, nausea, vomiting or diarrhoea
- Wheezing
Is Nytol safe to take while pregnant or breastfeeding?
Do not take Nytol if you are pregnant, planning on becoming pregnant or breastfeeding.
If you become pregnant while taking Nytol, inform your doctor as soon as possible.
Other safety information
Always speak to your doctor before you buy Nytol online from Prescription Doctor.
Please inform our doctor of all medicines you are currently taking, including those bought over the counter or prescribed by your doctor. You should also include any health and herbal supplements you are taking, such as St. John's Wort.
Do not take Nytol past the expiry date printed on the packaging. The date refers to the last day of the specific month. For example, "EXP: 12/25" means the 31st of December 2025.
Never throw away medicine via household or water waste. Take any unwanted or expired medication to your pharmacy and ask them dispose of them safely on your behalf.
Always store Nytol out of sight and reach from children and pets.
Never share your medicine with anybody else, even if they are experiencing the same symptoms or have been diagnosed with the same condition as you.
Frequently asked questions
What should I do if I forget to take Nytol when I should?
Nytol is taken when needed. If you forget to take it when you should, take it as soon as you remember. If it is nearly time for your next dose, skip the missed dose and continue to take Nytol as described in the leaflet. Do not take more Nytol to make up for a missed dose.
What should I do if I accidentally take more Nytol than I should?
If you take more Nytol than you should, inform your doctor right away or go straight to your nearest A&E department. Do not drive yourself there - ask someone to take you or call for an ambulance. Remember to take the packaging and any remaining medicine with you so that doctors know exactly what and how much you have taken.
Will Nytol affect my ability to drive or operate machinery?
Nytol causes drowsiness. Therefore, you should not drive or operate machinery after taking it.
Can I drink alcohol while taking Nytol?
Do not drink alcohol while taking Nytol. Drinking alcohol while taking Nytol can cause you to feel very drowsy and affect your breathing.
Will Nytol affect my fertility or contraception?
Nytol does not interact with hormonal contraceptives, including the combined pill, mini pill or morning after pill.
It is unlikely that Nytol will affect your fertility.
How long does Nytol take to work?
Nytol should make you feel drowsy between 20 and 30 minutes after taking it. If you do not feel drowsy after taking a dose of Nytol, do not take more. Inform your doctor or a pharmacist for advice.
How long does Nytol work?
The effects of Nytol last up to 6 hours.
Is Nytol addictive?
Nytol can be addictive if taken for longer than 2 weeks. It's important to take Nytol for the shortest time necessary. Speak to your doctor if you are concerned about addiction while taking Nytol.
If you feel you need assistance getting to sleep after 2 weeks of taking Nytol, speak to your doctor.
Can I take Nytol if I wake up in the middle of the night?
If you wake up in the middle of the night, you can take Nytol if you still have time to get a good 7 to 8 hours of sleep.
What should I do if Nytol doesn't work for me?
If Nytol does not work for you, speak to your doctor or a pharmacist. Do not take more Nytol in an attempt to make it more effective for you.
Can I take Nytol with other antihistamines?
If you are taking another antihistamine, such as fexofenadine or cetirizine, speak to your doctor before taking Nytol.
Can I take Nytol with painkillers?
It is safe to take Nytol with Ibuprofen and Paracetamol.
Taking Nytol with painkillers which contain codeine (such as co-codamol) can make you feel very sleepy. In this case, you should not drive, ride a bike, or operate machinery until you feel it is safe for you to do so.
Some painkillers may contain diphenhydramine. Always check the label and leaflet of other medicines you are taking to ensure you aren't accidentally taking more diphenhydramine than you should.
If you are unsure whether it safe to take Nytol with any other medication, ask a pharmacist.
Does Nytol cause weight gain?
There is no evidence to suggest that diphenhydramine, the active ingredient of Nytol, causes weight gain.
How much Nytol can I take?
You should not take more than the stated dose of 2 tablets (50mg) before bed. Do not take Nytol for longer than 2 weeks without first consulting with your doctor.
Where can I buy Nytol?
Nytol is an over-the-counter medicine available from your local pharmacy and some supermarkets.
If going to your pharmacist is an inconvenience for you, you can buy Nytol online from Prescription Doctor's online pharmacy.
All items available through our online service are dispatched from a UK based, GPhC registered pharmacy in the north of England. We take your privacy very seriously, ensuring all medicines are packaged in discreet packaging which gives no indication of its contents.
To begin your order, simply complete our short online questionnaire for our medical team to review. If your order is approved before 3pm, Monday to Friday, our pharmacy will dispatch your item the same day via a next-day tracked delivery service, courtesy of Royal Mail.
Table of contents
Sources
NHS, 2018. Diphenhydramine (including Nytol Original)
Omega Pharma Ltd, 2019. Nytol Original 25mg Tablets: SmPC
Treatment information
- Product Name: Nytol Original
- Manufacturer: Omega Pharma Ltd
- Active Ingredient(s): Diphenhydramine hydrochloride
- Administration: Oral
- Presentation: Tablets
- Available Strength: 25mg
- Exemption: Pharmacy
- Application: For treating insomnia in adults
- Dosage: Take 2 tablets (50mg) 20 minutes before bed
- Description: Nytol is a sleep aid which is used for temporary insomnia
- Drug Class: Antihistamine
- Alcohol Consumption: Do not drink alcohol
- When Pregnant: Do not take Nytol during pregnancy. Speak to your doctor for further advice.
- When Breastfeeding: Do not take Nytol while breastfeeding. Speak to your doctor for further advice.
- Price: 4.89 GBP
Click here to view the Nytol Original - Patient Information Leaflet
Authored & Reviewed By
Mohamed Imran Lakhi
MPharm - Lead Pharmacist
Imran Lakhi is the superintendent pharmacist and founder at Prescription Doctor. He has been at the core of our team.
Published on: 27/10/2020 Reviewed on: 13/03/2024
Published on: 27/10/2020 Reviewed on: 13/03/2024
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