Circadin contains synthesised Melatonin. Melatonin is released by the hypothalamus to induce and promote sleep, as per the circadian rhythm.
Circadin contains the synthetic version of the naturally occurring hormone melatonin.
Melatonin is a key hormone released by the body to induce and promote sleep. The Hypothalamus in the brain triggers the release of the hormone Melatonin as per the regular circadian rhythms and in periods of diminished light exposure such as that in the evening and night. Melatonin levels are high before sleep during the night and diminish almost completely during the day. It is thought that melatonin helps to fall and keep asleep.
Circadin contains the hormone Melatonin which is key in inducing and maintaining sleep. The melatonin is formulated in a prolonged released tablet which allows a steady release over 8 to ten hours. It is usually indicated for insomnia in patients over 55. However, it is safe and effective in temporary use for jet lag induced insomnia.
The onset of natural sleepiness is felt within 2 hours. The release of melatonin enables a better quality and longer sleep.
One tablet taken with food ONE to TWO hours before bedtime. The tablet should be swallowed whole and not crushed or broken. If crushed or broken, the duration of action will be reduced.
Only take as directed at night and do not take during the day.
Do not take Alcohol or other sleep inducing medications such as the Benzodiazepines
Circadin releases Melatonin gradually over 8 to 10 hours which increases the quality and length of sleep. It has a relatively quick onset of action and allows a natural progression to sleep. It also increases morning alertness and as it mimics the natural melatonin, it does not have an effect in the morning or during the day.
Circadin is relatively safe and well tolerated. According to the Circadin website, clinical trials show that it has a low incidence of adverse effects. There is no evidence which states that it causes dependence or even the daytime effects as seen with other hypnotic medication. There is a low incidence of impaired daytime concentration and can even improve daytime functioning.
Note: Circadin must not be taken with other sleep drugs such as:
Benzodiazepines Zolpidem, Zopiclone, Zaleplon
Please inform our Doctor if you are on any other medication, or suffer from other conditions such as:
It is not recommended to take this whilst you are Pregnant or Breast Feeding.
You may experience mild symptoms such as:-
Westward flights can have a negative impact on staying asleep whilst eastward flights can cause trouble falling asleep. It is recommended to:-
You can use Melatonin if you have a long overnight flight
Circadin has been rigorously trialled and tested to ensure it is safe and effective. Other melatonin supplements have not been tested and may contain varying amounts of unverified substances.
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Page last reviewed: June 2018
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