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About Product
Mohamed Imran Lakhi
This content has been written and checked for quality and accuracy by
Mohamed Imran Lakhi Content Administrator GPhC: 2060586 Updated on: 26/05/2020 Next review: 26/11/2020

What Is Diflucan?

Diflucan is an anti-fungal containing the active ingredient fluconazole that is prescribed for the prevention and treatment of fungal infections such as candidiasis and dermatomycosis infections such as Athletes foot (tinea pedis), ringworm (tinea corporis), and jock itch (tinea cruris). Diflucan is available as hard capsules as well as an oral suspension.

Diflucan can be bought with confidence from Prescription Doctor. Our qualified doctors are on hand to answer any questions you may have and our UK registered pharmacy ensures you only get high quality, licensed medicine from reputable vendors. If your order is processed before 3pm, Monday to Friday, your item will be dispatched the same day, aimed for a next-day delivery.

How Does Diflucan Work?

Fluconazole, the active ingredient in Diflucan, stops fungal growth by interfering with the ability of yeasts and fungi to produce ergosterol. Ergosterol makes up the cell membrane of the yeasts and fungi, without which, the membrane becomes vulnerable, and holes appear in the membrane. The cells within leak out through the holes, die, and cannot grow. By killing off and inhibiting the growth of the cells, Diflucan effectively prevents and clears up any fungal infections.

Diflucan is quite fast-acting, and you should experience relief for your symptoms within a day of taking the medicine. Use Diflucan as prescribed for complete symptom relief and a full recovery. Diflucan is also very effective in preventing the recurrence of fungal infections.

How to Take Diflucan

Swallow the Diflucan capsule whole with a glass of water. For the oral suspension, ensure that you shake well before use. The recommended dosage for Diflucan may vary depending on the type of infection. You can take Diflucan with or without food.

Always take Diflucan as prescribed by your doctor.

Side effects and cautions

Before taking Diflucan, it's important to familiarise yourself with the information within the patient information leaflet (PIL) enclosed with your medicine. You should keep this leaflet in case you need to refer to it in the future.


If you allergic to fluconazole or any of the other ingredients listed in the patient information leaflet, or if you have experienced an allergic reaction to other antifungal treatments, do not take Diflucan.

If you experience the signs and symptoms of an allergic reaction, cease treatment with Diflucan and seek immediate medical attention by going to the accident and emergency department of your nearest hospital. Signs of allergic reaction may include:

  • Abdominal pain
  • Diarrhoea
  • Difficulty breathing
  • Difficulty swallowing
  • Itchy, red, watery eyes
  • Raised, red, itchy rash (hives)
  • Swelling of the lips, face, tongue, eyes or throat
  • Vomiting
  • Wheezing and tightness of chest

Diflucan contains lactose - a sugar found in milk. If you have an intolerance to some sugars (referred to as lactose intolerance), speak to your doctor before taking Diflucan.


Do not take Diflucan if you are taking any of the following medicine:

  • Astemizole or terfenadine (antihistamines used to treat allergies)
  • Cisapride
  • Erythromycin
  • Pimozide
  • Quinidine

There may be interactions between Diflucan and other medicine you take, which may impact the mechanism of Diflucan and other medicine. Information pertaining these interactions can be found within the patient information leaflet (PIL).

Talk to your doctor before taking Diflucan if you:

  • develop signs of 'adrenal insufficiency' such as abdominal pain, chronic fatigue, loss of appetite, muscle weakness or weight loss
  • develop skin reactions (itching, reddening of the skin or difficulty breathing)
  • have abnormal levels of potassium, calcium or magnesium in your blood
  • have problems with your liver or kidneys
  • suffer from heart disease, including heart rhythm problems (such as arrhythmia)

Pregnancy and breastfeeding

Speak to your doctor before taking Diflucan if you are pregnant, think you might be pregnant, or breastfeeding.

Side effects

All medicines carry the risk of side effects, though not everybody gets them. It is important to be aware of the potential risks posed by medicine and remain vigilant of any possible side effects during your course of treatment.

Common side effects (may affect up to 1 in 10 people):

  • headache
  • increases in blood tests of liver function
  • rash
  • stomach ache, diarrhoea, nausea and vomiting

Uncommon side effects (may affect up to 1 in 100 people):

  • constipation, digestion difficulty, wind, dry mouth
  • decreased appetite
  • dizziness, spinning sensation, tingling, prickling, numbness, changes in sense of taste
  • drowsiness
  • fatigue, general feeling if being unwell, fever
  • fits
  • increased perspiration (sweating)
  • insomnia
  • live damage, which can cause yellowing of the skin and whites of the eyes (jaundice)
  • muscle pain
  • raised, lumpy, lumpy rash (hives)
  • reduction in red blood cells which can make skin pale and cause weakness of breathlessness

Rare side effects (may affect up to 1 in 1,000 people):

  • abnormal electrocardiogram (ECG), change in heart rate or rhythm
  • allergic reaction
  • blood chemistry changes
  • decrease in white blood cell count
  • hair loss
  • liver failure
  • low blood potassium levels
  • red or purple discolouration of the skin
  • shaking

This is not an exhaustive list of side effects, Further information regarding the safety of this medicine can be found in the patient information leaflet.

Reporting side effects

If you experience any side effects, whether listed above or in the patient information leaflet, you should report them to your doctor as soon as possible. Alternatively, you can speak to a pharmacist about your medicine and any concerns you may have.

Do not discard unwanted, unused or expired medicine via household waste or water waste. Take this medicine to your nearest pharmacist and ask them to dispose of them safely on your behalf.

You can find your nearest pharmacy by using the NHS' Find A Pharmacy website.

Always keep medicine out of the sight and reach of children and pets.

Never share your medicine with anyone else, even if they are experiencing the same symptoms or condition as you.

Frequently Asked Questions

What should I do if I forget to take Diflucan when I should?

If you forget to take Diflucan when you should, do so as soon as you remember. If it's almost time for your next dose, then you can skip the missed dose, and take Diflucan as you normally would. Do not take more Diflucan to make up for a missed dose.

What should I do if I take too much Diflucan?

Seek medical attention immediately if you take more Diflucan than what has been prescribed.

Can I drink alcohol while taking Diflucan?

While it is highly unlikely that alcohol will interfere with the effectiveness of Diflucan, it may exacerbate possible side effects such as headache and stomach ache. It is therefore advised that you limit or avoid alcohol consumption while taking Diflucan.

Will Diflucan affect my ability to drive or operate machinery?

Diflucan may cause dizziness or seizures. Refrain from driving and operating machinery until you establish how Diflucan affects you. If it does affect you, then you should wait until you are done with the treatment to resume driving and operating machinery.

How long does Diflucan take to work?

Diflucan capsules take 3 days to work.

You should continue to take Diflucan until your infection has cleared up.

How long does Diflucan stay in your system?

It usually takes between 6 and 9 days for Diflucan to exit your system.

Where can I buy Diflucan over-the-counter?

Diflucan is only available on prescription and cannot be bought over-the-counter.

Private online doctor's services, such as Prescription Doctor, can issue prescriptions for you. Just fill out our short medical questionnaire and our registered doctor will review your case and issue a prescription if suitable.

Table of contents

What is Diflucan?

How does Diflucan work?

How to take Diflucan?

Side effects and cautions

Frequently asked questions

Treatment information

  • Product Name: Diflucan
  • Manufacturer: Pfizer
  • Active Ingredient(s): Fluconazole
  • Administration: Oral
  • Presentation: Hard capsules
  • Available Strength: 150mg
  • Exemption: Prescription only
  • Application: Men and women over 18+
  • Dosage: Take one 150mg capsule once weekly for up to 6 weeks
  • Description: Diflucan is an antifungal treatment which is used to treat a number of fungal infections
  • Drug Class: Antifungal
  • Alcohol Consumption: No influence
  • When Pregnant: Inform our prescriber if you are pregnant or think you might be pregnant before taking Diflucan.
  • When Breastfeeding: Inform our prescriber if you are breastfeeding before taking Diflucan.
Click here to view the Diflucan - Patient Information Leaflet
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