Aciclovir cream

What is Aciclovir Cream?

Aciclovir cream is a topical cream used to treat cold sores, which contains the antiviral also known as aciclovir.

It is the generic alternative to Zovirax cream, which is marketed by GlaxoSmithKline (GSK).

With Prescription Doctor, you can safely buy aciclovir cream online after completing an online consultation. To begin your order, please fill out our online medical questionnaire, which will be reviewed by one of our doctors.

If your order is approved before 3pm on a weekday, our UK-regulated pharmacy will dispense your medicine and dispatch the aciclovir cream to your door via discreet, next-day delivery.

What are Cold Sores? 

Cold sores appear as small, fluid-filled blisters on the lips or surrounding areas of the face.

Cold sores are caused by the herpes simplex virus (HSV-1). The herpes virus is contagious and is often spread through kissing or oral sex. HSV-1 is very common. The World Health Organization estimates that around 64% of people under 50 globally have HSV-1.

If you are unsure whether you have herpes, you can get an STI test. If herpes is suspected and you have a visible blister or sore, a clinician can take a swab for testing.

When the herpes virus infects the body, it targets nerve cells and tissues around the face, causing the outbreak of cold sores.

Although the immune system initially attacks the virus, the body doesn't completely eliminate the virus.

The herpes virus can remain dormant in nerve cells and tissue for months or years, then resurface, occasionally causing recurrent outbreaks when the body is exposed to triggers. Some common triggers for recurrent outbreaks include stress, menstruation, and sunlight exposure.

There is currently no cure to permanently eliminate the herpes virus from the body and prevent cold sore outbreaks, but there are antiviral medications that can treat symptoms and accelerate healing during an outbreak.

Treatment should be started immediately to improve symptoms such as itching, pain, and unsightly cold sores.

How Does Aciclovir Cream Work?

The antiviral agent aciclovir prevents the herpes virus from multiplying at the site of infection.

Aciclovir is converted to its active form inside HSV-infected cells, where it interferes with viral DNA replication and slows viral replication.

While aciclovir cream helps to improve the recovery time of a flare-up, it doesn't prevent the spread of herpes.

How Long Does Aciclovir Cream Take to Work?

Aciclovir cream starts working against the cold sore virus soon after it is applied. However, it can take several days for the cold sore to noticeably improve.

If your cold sore has not fully healed after 10 days, or has worsened, stop using the cream and speak to your doctor. 

How to Use Aciclovir Cream

Apply Aciclovir cream at the first signs of a cold sore, such as tingling and itching. You can still use the medication during the blister stage. Wash your hands before application and do not touch your eyes until you have washed your hands again after use. Do not apply the treatment inside your mouth, nose, eyes, or to the genital area.

Take care to only apply the cream to the affected skin and surrounding areas. Clean and dry the skin before application.

Apply the medication liberally to the affected area 5 times a day. Continue treatment for 4 full days to ensure rapid healing. If your cold sore hasn’t healed after this time, carry on using Aciclovir cream for up to a further 6 days (up to 10 days total).

More information about Aciclovir Cream and how to use it can be found on the NHS website. 

What if I Apply Too Much Aciclovir Cream?

Do not use more than the recommended dose of Aciclovir Cream. If you accidentally swallow the medication, it is unlikely to cause any adverse effects. Consult your clinician or doctor if you’re concerned. 

If You Forget to Apply Aciclovir Cream

If you miss your dose of aciclovir cream, apply the missed dose as soon as you remember. Continue to administer the remaining doses for the day. Do not apply more cream to make up for the missed dose.

If You Get Aciclovir Cream in Your Eye

If you accidentally get cream in your eye, wash out thoroughly with warm water. Seek medical advice from your clinician or doctor if you’re concerned. 

Aciclovir Cream Side Effects and Cautions

Before using Aciclovir Cream, read the Patient Information Leaflet that comes with the treatment. All medicines carry the risk of side effects, though not everyone experiences them. That said, it’s still a good idea to understand what you could expect before starting treatment.

Potential Aciclovir Cream side effects include:

• Mild burning or stinging after application. This will quickly subside. 
• Redness, itching, or mild drying or flaking of the skin
• Skin rashes, hives, or wheals

If you experience allergy-like reactions, such as swelling of the lips, face, and eyelids, stop using the medicine and tell your clinician or doctor. 

Aciclovir Cream Warnings and Interactions 

Aciclovir cream is not suitable for everyone. If you’re unsure whether you should use it, consult your clinician or doctor.

Do not use the medication:

• If you have ever had an allergic reaction to aciclovir, valaciclovir, or any of the other ingredients
• Inside your mouth or nose
• For any skin infection other than a cold sore
• In the eyes or genital area

Tell your clinician or doctor if you have been advised that you have a weakened immune system. Also tell them if you take any regular medication, prescription, over-the-counter, or herbal.

Aciclovir Cream is for single-patient use only and should not be shared with other people. 

Pregnancy and Breastfeeding

Speak to your clinician or doctor before using Aciclovir Cream if you are pregnant, trying to become pregnant, or are breastfeeding. 

Other Safety Information

Do not use Aciclovir 5% cream after the expiry date shown on the container, and use within 6 weeks of opening the medication. Keep the treatment in its original packaging and store below 25°C. Avoid refrigeration or storing in the freezer.

Keep Aciclovir Cream out of the sight and reach of children. Do not dispose of it via household or water waste, as this can harm the environment. Take any unwanted or expired medication to your local pharmacy and ask them to dispose of it safely on your behalf.

Frequently Asked Questions

Will Aciclovir Cream Affect My Ability to Drive or Operate Machinery?

Aciclovir cream should not affect your ability to drive or operate machinery.

Can I Drink Alcohol While Using Aciclovir Cream?

Yes, you can drink alcohol while using aciclovir cream. Avoid drinking more than 14 units of alcohol per week.

Can I Have Sex While Using Aciclovir Cream?

You should avoid kissing and oral sex if you or your partner has cold sores.

In the case of genital herpes, you and your partner should avoid sex until the blisters have completely healed.