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Colgate Duraphat Toothpaste

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Prices from £13.99
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You must complete a short online consultation so that our prescriber can ensure that the treatment is suitable for you.
Order now to receive your order Saturday, June 03
How to order
  1. Click on the green "Back To Get Started" button, then click "Start Consultation" button on the next page.
  2. Fill in our short consultation form.
  3. Choose delivery method and mode of payment.
  4. Our team of expert prescribers will assess whether medication is suitable.
  5. If you get the green light and it is deemed suitable, your order will be processed quickly and efficiently.
Confidential Service

Your privacy is important, Prescription Doctor are committed to keeping your details completely confidential.

This is why we also take steps to conceal your prescription products under two layers of packaging.

Delivery and Packing
Discreet Delivery?

We have a commitment to delivering a discreet service and understand your need for privacy. We ship all orders via a trackable courier using discreet, plain packaging.

Do I Need to Wait in All Day for Delivery?

Once your order is dispatched you will receive a tracking number via sms and email.

Do You Deliver on Weekends?

We deliver medications between Monday and Saturday. You can upgrade to Saturday delivery on Friday.

My Order Hasn’t Arrived What Should I Do?

You should receive a tracking number with your order which you can use this number to track your parcel online. This should give you a clear indication of where your parcel is. If you haven’t received your parcel in the time frame given by our couriers, contact your local depot to find out where it is. You can also contact our support team who will do this for you.

Can I Be Notified by Text?

On checkout you will be asked to leave your mobile number so our courier can text you about the delivery. This is also useful if the courier has problems finding your address. We will not use your mobile number for anything else.

Payment Methods
How Can I Pay for My Order?

You can pay for your order using credit, debit card or via bank transfer.

I Don’t Have a Credit Card, How Can I Pay?

If you don’t have a credit or debit card you can pay via bank transfer. We will give you a unique reference number at checkout along with details of how to make the transfer. Once the money has cleared in our account, we will process your order.

How Do You Keep My Details Safe?

We are a completely secure site and take many measures to ensure your details are kept safe. We understand that you have a right to extreme privacy when purchasing sensitive health medications. All information that you provide to us is stored on our secure servers. Any payment transactions will be encrypted using SSL technology.

Payment and refunds?

You can pay for your order using credit, debit card and bank transfer.

Card Payment: Please notify us that you wish to cancel your order. Your refund will show available In 1 - 3 days.

Bank Transfer: A member of our team will contact you requesting for your bank details. These details are only used to transfer the funds back into your account.

Treatment Information

Table of contents

How Our Service Works

With Prescription Doctor, you can renew your prescription for Duraphat 5000 high fluoride toothpaste online.

To begin your consultation, fill out our online medical form for one of our doctors to review.

If our doctor approves your order before 3 pm on a weekday, our UK-registered pharmacy will dispense and dispatch your item for delivery tomorrow.

What is Duraphat 5000 Toothpaste Used For?

Duraphat 5000 is a concentrated form of toothpaste containing a higher level of fluoride than ordinary toothpaste. The fluoride helps to reduce tooth decay and promotes healthy teeth and gums.  It is used by adults and children over 16 years old at risk of tooth decay.

Tooth decay is also known as dental caries and occurs when dental plaque turns sugars into acid, causing damage to the tooth. If plaque starts to build up, it can lead to other problems, such as holes in the teeth (cavities) and gum disease.

Tooth decay can happen at any age due to poor diet or dental hygiene. As well as tooth decay, poor oral hygiene can lead to other issues, such as discolouration of the teeth and physical pain from toothache.

Brushing your teeth daily with fluoride toothpaste is one of the most effective ways of preventing tooth decay.

For people at a higher risk of tooth decay, their dentist may prescribe stronger toothpaste such as Duraphat 2500 or Duraphat 5000.

To learn more about tooth decay, visit the NHS website. 

How Does Duraphat 5000 work?

Colgate Duraphat Toothpaste is formulated with 5,000 parts per million (ppm) of fluoride, which protects your teeth from cavities by reinforcing the enamel on your teeth. Fluoride binds to the minerals in the saliva and starts to remineralize the tooth surfaces, making them more resistant to decay.

This helps protect the teeth from sugar acids and bacteria. When brushing with Colgate Duraphat Toothpaste, it also helps remove plaque on the tooth surfaces.

Once you start using Duraphat 5000, it will help prevent the spread of tooth decay by rebuilding the tooth's enamel.

It is essential to visit your dentist regularly so early tooth decay can be detected and treated as soon as possible.

  • Fluoride helps protect against cavities and tooth decay caused by acid attacks on your teeth.
  • Regular use of Colgate Duraphat 5000 helps strengthen teeth, promoting a healthy and confident smile.
  • It helps rebuild weakened areas of the enamel, promoting a more even, natural white colour to your teeth.
  • The toothpaste also helps reduce tooth sensitivity and prevents the build-up of plaque.

You can find a dentist near you by visiting the NHS and entering your postcode. 

How Do I Use Duraphat 5000?

You should use Duraphat 5000 toothpaste as your dentist or doctor has prescribed. If you are unsure how to use this product, ask your dentist or doctor.

You should use Colgate Duraphat 5000 instead of your regular toothpaste and brush your teeth after every meal.

You can use a manual or electric toothbrush when using Duraphat 5000.

Gently squeeze a 2 cm ribbon onto your toothbrush, which provides between 3 mg and 5 mg of fluoride.

Brush your teeth evenly in a vertical motion, from the gum to the tip of the tooth, for approximately 3 minutes. Make sure to spit out excess foam.

Do not swallow the foam or the toothpaste.

Once you have used the toothpaste, replace the cap and store the toothpaste away from children.

Side effects and cautions of Duraphat 5000 toothpaste

Before using Duraphat 5000, it's essential to read the leaflet supplied with your medicine. This leaflet provides instructions on using and storing the treatment and vital safety information such as contraindications and side effects.

If you have concerns about anything you read in the supplied leaflet, speak to your doctor, dentist or pharmacist for advice.

Side effects of Duraphat 5000

Duraphat 5000 is generally well-tolerated and unlikely to cause side effects.

Rare side effects of Duraphat 5000 (may affect less than 1 in 1,000 people):

  • Burning oral sensation
  • Allergic reaction

Unknown frequency (frequency cannot be determined from available data):

  • Dental fluorosis

If you experience any side effects, whether listed above or in the accompanying leaflet, you should speak to your doctor, dentist or pharmacist.


Do not use Duraphat 5000 toothpaste if you are allergic to sodium fluoride or other ingredients listed in the patient information leaflet.

If you experience the signs of an allergic reaction, stop using Duraphat 5000 toothpaste and seek urgent medical attention by going straight to your nearest hospital's accident and emergency department. Remember to take any packaging and remaining medicine with you so that doctors know what you have taken.

Signs of an allergic reaction include:

  • Chest tightening
  • Dry, red and cracked skin
  • Itchy, red, watery eyes
  • Itchy, raised, red rash (hives)
  • Swelling of the lips, tongue, eyes or face
  • Tummy pain, nausea, vomiting or diarrhoea
  • Wheezing

Pregnancy and breastfeeding

If you are pregnant, think you might be pregnant, or breastfeeding, speak to your doctor or dentist before using Duraphat 5000 toothpaste.

Other safety information

Please inform our prescriber of all medicines you are currently taking, including those prescribed by your doctor or bought over the counter and health and herbal supplements.

Do not use Duraphat 5000 toothpaste past the expiry printed on the packaging. The date refers to the last day of the specified month.

Never throw away medicine via household or water waste. Take any unwanted or expired medication to your pharmacy and ask them to dispose of it safely.

Always store Duraphat 5000 toothpaste out of sight and reach from children and pets.

Never share your medicine with anybody else, even if they are experiencing the same symptoms or have the same condition.

Frequently Asked Questions

Colgate Duraphat 5000 Superdrug

Colgate Duraphat 5000 is avaiable from Superdrug pharmacy.

Can I drink alcohol while taking Duraphat 5000?

Yes, you can drink alcohol while using Duraphat 5000 toothpaste. However, avoid excessive alcohol consumption.

Will Duraphat 5000 impact my ability to drive or operate machinery?

Duraphat 5000 should not impact your ability to drive or operate any machinery.

Can I use mouthwash with Duraphat 5000?

You should avoid rinsing your mouth with water or mouthwash after using Duraphat 5000, as this may reduce the effectiveness of the fluoride.

Are there any dietary requirements?

You should avoid sugary foods and drinks to prevent tooth decay, and avoid eating or drinking anything for up to 30 minutes after brushing your teeth with Duraphat 5000.

How effective is Duraphat 5000?

In clinical studies, Duraphat 5000 reduced caries by more than 75%.

How long does a tube of Duraphat 5000 last?

One tube of Duraphat should last approximately one month.

What should I do if I forget to take Duraphat 5000 when I should?

If you forget to use Duraphat 5000 when you should, use it as soon as you remember. If it is almost time for your next dose, skip the missed dose and use Duraphat at the next usual time.

Do not use more Duraphat to make up for the missed dose.

What should I do if I use too much Duraphat 5000?

If you use more Duraphat than you should over a long period, you may develop staining of the teeth, known as dental fluorosis.

Can you buy Colgate Duraphat 2800 / 5000 from Tesco?

Colgate Duraphat 2800 / 5000 is unavailable to buy over the counter from Tesco because it is a prescription-only medication. 




NHS, 2019. Tooth Decay

Colgate, 2018. Colgate Duraphat 5000ppm Fluoride Toothpaste.

Additional Information

How to remove tooth decay yourself

Mohamed Imran Lakhi
This content has been written and checked for quality and accuracy by Mohamed Imran Lakhi Content Administrator Updated on: 31/05/2023 Next review: 01/12/2023

Treatment information

  • Product Name: Colgate Duraphat
  • Manufacturer: Colgate-palmolive
  • Active Ingredient(s): Sodium Fluoride
  • Administration: Dental
  • Presentation: Toothpaste
  • Available Strength: 2800ppm or 5000ppm
  • Exemption: Prescription-only
  • Dosage: Apply 2cm of paste to your toothbrush. Brush for 3 minutes after every meal.
  • Description: Colgate Duraphat 5000 is a toothpaste which contains a high concentration of fluoride, which helps to prevent tooth decay and protect teeth enamel.
  • Drug Class: Minerals (Fluoride supplement)
  • Alcohol Consumption: No influence. Avoid excessive alcohol consumption.
  • When Pregnant: Speak to your doctor before using Duraphat if you are pregnant or think you might be pregnant.
  • When Breastfeeding: Speak to your doctor before using Duraphat if you are breastfeeding.
  • Price: 13.99 GBP
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Click here to view the Colgate Duraphat Toothpaste - Patient Information Leaflet

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