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You must complete a short online consultation so that our prescriber can ensure that the treatment is suitable for you.
Order now to receive your order Wednesday, September 28
How to order
  1. Click on the green "Start Order" button.
  2. Fill in our short consultation form.
  3. Choose delivery method and mode of payment.
  4. Our team of expert prescribers will assess whether medication is suitable.
  5. If you get the green light and it is deemed suitable, your order will be processed quickly and efficiently.
Confidential Service

Your privacy is important, Prescription Doctor are committed to keeping your details completely confidential.

This is why we also take steps to conceal your prescription products under two layers of packaging.

Delivery and Packing
Discreet Delivery?

We have a commitment to delivering a discreet service and understand your need for privacy. We ship all orders via a trackable courier using discreet, plain packaging.

Do I Need to Wait in All Day for Delivery?

Once your order is dispatched you will receive a tracking number via sms and email.

Do You Deliver on Weekends?

We deliver medications between Monday and Saturday. You can upgrade to Saturday delivery on Friday.

My Order Hasn’t Arrived What Should I Do?

You should receive a tracking number with your order which you can use this number to track your parcel online. This should give you a clear indication of where your parcel is. If you haven’t received your parcel in the time frame given by our couriers, contact your local depot to find out where it is. You can also contact our support team who will do this for you.

Can I Be Notified by Text?

On checkout you will be asked to leave your mobile number so our courier can text you about the delivery. This is also useful if the courier has problems finding your address. We will not use your mobile number for anything else.

Payment Methods
How Can I Pay for My Order?

You can pay for your order using credit, debit card or via bank transfer.

I Don’t Have a Credit Card, How Can I Pay?

If you don’t have a credit or debit card you can pay via bank transfer. We will give you a unique reference number at checkout along with details of how to make the transfer. Once the money has cleared in our account, we will process your order.

How Do You Keep My Details Safe?

We are a completely secure site and take many measures to ensure your details are kept safe. We understand that you have a right to extreme privacy when purchasing sensitive health medications. All information that you provide to us is stored on our secure servers. Any payment transactions will be encrypted using SSL technology.

Payment and refunds?

You can pay for your order using credit, debit card and bank transfer.

Card Payment: Please notify us that you wish to cancel your order. Your refund will show available In 1 - 3 days.

Bank Transfer: A member of our team will contact you requesting for your bank details. These details are only used to transfer the funds back into your account.

About Product
Mohamed Imran Lakhi
This content has been written and checked for quality and accuracy by
Mohamed Imran Lakhi Content Administrator Updated on: 08/12/2021 Next review: 08/06/2022

How Our Service Works

With Prescription Doctor, you can renew your prescription for Duraphat 5000 high fluoride toothpaste online.

To begin your consultation, simply fill out our online medical form for one of our doctors to review.

If our doctor approves your order before 3 pm on a weekday, our UK registered pharmacy will dispense and dispatch your item for delivery tomorrow.

What is Duraphat 5000 Toothpaste Used For?

Duraphat 5000 is a concentrated form of toothpaste containing a higher level of fluoride than ordinary toothpaste. It is used by adults and children over 16-years-old who are at risk of tooth decay.

Tooth decay is also known as dental caries and occurs when dental plaque turns sugars into acid, causing damage to the tooth. If plaque starts to build up, it can lead to other problems too, such as holes in the teeth (cavities) and gum disease.

Tooth decay can happen at any age due to poor diet, or poor dental hygiene. As well as tooth decay, poor oral hygiene can also lead to other issues, such as discolouration of the teeth, and physical pain from toothache.

Thoroughly brushing your teeth daily with fluoride toothpaste is one of the most effective ways of preventing tooth decay.

For people at a higher risk of tooth decay, their dentist may prescribe stronger toothpaste such as Duraphat 2500 or Duraphat 5000.

To learn more about tooth decay, visit the NHS website. 

How Does Duraphat 5000 work?

Duraphat 5000 toothpaste contains the active ingredient sodium fluoride, which helps to prevent discolouration of teeth and tooth decay.

When you eat sugar, the bacteria in plaque create an acid. This acid damages the protective enamel of teeth, contributing to tooth decay. Tooth decay can lead to toothache and make eating difficult.

Sodium fluoride helps to protect teeth by strengthening the enamel, making teeth more resistant to the acids from plaque that can lead to tooth decay. Fluoride also prevents mineral loss in teeth and replenishes the number of minerals our teeth need to protect against plaque.

Once you start using Duraphat 5000, it will help prevent the spread of tooth decay by rebuilding the tooth’s enamel.

It is important to visit your dentist regularly so early tooth decay can be detected and treated as soon as possible.

You can find a dentist near you by visiting the NHS and entering your postcode. 

How Do I Use Duraphat 5000?

You should use Duraphat 5000 toothpaste as your dentist or doctor has prescribed. If you are unsure about how to use this product, ask your dentist or doctor.

You should use Duraphat 5000 toothpaste instead of your regular toothpaste and brush your teeth with it after every meal.

You can use a manual or electric toothbrush when using Duraphat 5000.

Gently squeeze out a 2 cm ribbon onto your toothbrush, which provides between 3 mg and 5 mg of fluoride.

Brush your teeth evenly in a vertical motion, from the gum to the tip of the tooth for approximately 3 minutes. Make sure to spit out excess foam.

Do not swallow the foam or the toothpaste.

Once you have used the toothpaste, replace the cap and store the toothpaste away from children.


Side effects and cautions of Duraphat 5000 toothpaste

Before using Duraphat 5000, it's important to read the leaflet supplied with your medicine. This leaflet provides instructions on how to use and store the medicine, as well as important safety information such as contraindications and side effects.

If you have concerns about anything you read in the supplied leaflet, speak to your doctor, dentist or pharmacist for advice.

Side effects of Duraphat 5000

Duraphat 5000 is generally well-tolerated and unlikely to cause side effects.

Rare side effects of Duraphat 5000 (may affect less than 1 in 1,000 people):

  • Burning oral sensation
  • Allergic reaction

Unknown frequency (frequency cannot be determined from available data):

  • Dental fluorosis

If you experience any side effects, regardless of whether they are listed above or in the accompanying leaflet, you should inform your doctor, dentist or speak to a pharmacist.


Do not use Duraphat 5000 toothpaste if you are allergic to sodium fluoride or any of the other ingredients listed in the patient information leaflet.

If you experience the signs of an allergic reaction, stop using Duraphat 5000 toothpaste and seek urgent medical attention by going straight to the accident and emergency department of your nearest hospital. Remember to take any packaging and remaining medicine with you so that doctors know exactly what you have taken.

Signs of an allergic reaction include:

  • Chest tightening
  • Dry, red and cracked skin
  • Itchy, red watery eyes
  • Itchy, raised, red rash (hives)
  • Swelling of the lips, tongue, eyes or face
  • Tummy pain, nausea, vomiting or diarrhoea
  • Wheezing

Pregnancy and breastfeeding

If you are pregnant, think you might be pregnant, or breastfeeding, speak to your doctor or dentist before using Duraphat 5000 toothpaste.

Other safety information

Please inform our doctor of all medicines you are currently taking, including those prescribed by your doctor, or bought over the counter, as well as health and herbal supplements.

Do not use Duraphat 5000 toothpaste past the expiry printed on the packaging. The date refers to the last day of the specified month.

Never throw away medicine via household or water waste. Take any unwanted or expired medication to your pharmacy and ask them to dispose of it safely on your behalf.

Always store Duraphat 5000 toothpaste out of sight and reach from children and pets.

Never share your medicine with anybody else, even if they are experiencing the same symptoms or have the same condition as you.

Frequently Asked Questions

Can I drink alcohol while taking Duraphat 5000?

Yes, you can drink alcohol while using Duraphat 5000 toothpaste. However, avoid excessive alcohol consumption.

Will Duraphat 5000 impact my ability to drive or operate machinery?

Duraphat 5000 should not impact your ability to drive or operate any machinery.

Can I use mouthwash with Duraphat 5000?

You should avoid rinsing your mouth with water or mouthwash after using Duraphat 5000, as this may reduce the effectiveness of the fluoride.

Are there any dietary requirements?

You should avoid sugary foods and drinks to prevent tooth decay, and avoid eating or drinking anything for up to 30 minutes after brushing your teeth with Duraphat 5000.

How effective is Duraphat 5000?

In clinical studies, Duraphat 5000 was shown to reduce caries by more than 75%.

How long does a tube of Duraphat 5000 last?

1 tube of Duraphat should last approximately 1 month.

What should I do if I forget to take Duraphat 5000 when I should?

If you forget to use Duraphat 5000 when you should, use it as soon as you remember. If it is almost time for your next dose, skip the missed dose and use Duraphat at the next usual time.

Do not use more Duraphat than you normally would to make up for the missed dose.

What should I do if I use too much Duraphat 5000?

If you use more Duraphat than you should over a long period, you may develop staining of the teeth known as dental fluorosis.

Can you buy Colgate Duraphat 2800 / 5000 from Tesco?

Colgate Duraphat 2800 / 5000 is not available to buy over the counter from Tesco. This is because Colgate Duraphat 2800 / 5000 ppm is a prescription-only medcation. 




NHS, 2019. Tooth Decay

Colgate, 2018. Colgate Duraphat 5000ppm Fluoride Toothpaste.

Treatment information

  • Product Name: Colgate Duraphat
  • Manufacturer: Colgate-palmolive
  • Active Ingredient(s): Sodium Fluoride
  • Administration: Dental
  • Presentation: Toothpaste
  • Available Strength: 2800ppm or 5000ppm
  • Exemption: Prescription-only
  • Dosage: Apply 2cm of paste to your toothbrush. Brush for 3 minutes after every meal.
  • Description: Colgate Duraphat 5000 is a toothpaste which contains a high concentration of fluoride, which helps to prevent tooth decay and protect teeth enamel.
  • Drug Class: Minerals (Fluoride supplement)
  • Alcohol Consumption: No influence. Avoid excessive alcohol consumption.
  • When Pregnant: Speak to your doctor before using Duraphat if you are pregnant or think you might be pregnant.
  • When Breastfeeding: Speak to your doctor before using Duraphat if you are breastfeeding.
Click here to view the Duraphat - Patient Information Leaflet

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