Vitamins to Take on Mounjaro: The Complete Guide

Mounjaro (tirzepatide) is one of several highly effective weight loss treatments available on prescription in the UK. The medication works by suppressing appetite and making you feel fuller for longer, thereby helping to reduce calorie consumption.

Numerous clinical studies have found that Mounjaro can promote significant weight loss, especially when used as part of a weight management plan with regular exercise and a reduced-calorie diet. Indeed, the treatment has produced some impressive before-and-after success stories and helped countless individuals achieve their goals.

While it’s certainly true that following a balanced diet while using Mounjaro may enhance weight loss, some research projects have highlighted some potential issues that may need to be addressed. One study found that people on weight loss injections often consume fewer vital nutrients and may be at risk of deficiencies.

So, the question is, do you need to take vitamins with Mounjaro, or will a healthy lifestyle suffice? In this article, we’ll answer that very question and provide guidance on what vitamins to take on Mounjaro, should you decide to go down that route. Let’s get started. 

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Do You Need to Take Vitamins with Mounjaro?

Mounjaro may affect your nutrient intake, so some people might benefit from taking dietary supplements while using this medication. However, not everyone needs to take vitamins with Mounjaro. It primarily depends on your diet and how your body responds to the medication. If you’re at all unsure, you can consult a clinician for advice.

Mounjaro promotes weight loss by slowing the movement of food through the stomach and suppressing appetite. People using weight loss treatments typically eat fewer and smaller meals than usual, which can increase their risk of vitamin and mineral deficiencies. This is especially true for people with poor diets, i.e. those high in energy-dense but low-nutrient foods. If this is the case for you, then you may benefit from taking vitamins on Mounjaro.

Your body’s reaction to Mounjaro will also determine whether you need to take dietary supplements. Gastrointestinal symptoms, including diarrhoea and vomiting, are common side effects of tirzepatide treatment. Diarrhoea increases the speed at which food moves through the intestines, making it harder for your body to extract vital nutrients from your diet. This can lead to nutrient deficiencies over time, the signs of which include:

• Unusual fatigue
• Excessive hair loss
• Flaky skin
• Itchy skin
• Muscle weakness
• Poor wound healing
• Unusual bruising

If Mounjaro restricts your diet or causes diarrhoea, or you have any of the symptoms listed above, you may need to take supplemental vitamins and minerals. But what are the vitamins to take on Mounjaro, and are there any to avoid? 

What Vitamins Should I Take on Mounjaro?

There is no official list of vitamins to take on Mounjaro, and you should consult a healthcare professional if you want personalised nutritional advice. However, studies have found that people using weight loss injections often lack adequate fibre, calcium, magnesium, potassium, choline, and vitamins A, C, D, E and K in their diets.

Taking a daily multivitamin may help reduce your risk of deficiencies while using Mounjaro. These contain a combination of vitamins and minerals, and could help you reach your required daily nutrient intake. You may also benefit from taking a fibre supplement, which can help to address other potential Mounjaro side effects such as constipation.

People on Mounjaro often lose a significant amount of weight in a relatively short space of time. This can have numerous health benefits, but rapid weight loss also carries risks, such as decreased bone density. For this reason, clinical guidelines recommend the use of vitamin D and calcium supplements for people undergoing tirzepatide treatment. Calcium is critical for bone health, and vitamin D plays a key role in helping the body to absorb calcium.

You may also need to consider your protein intake on Mounjaro, especially if your diet is low in protein-rich foods (like meat, dairy products, and beans). Tirzepatide treatment is associated with significant reductions in both fat and muscle tissue, and reduced muscle mass can lead to other problems with strength and physical mobility. Protein shakes and powders can be a convenient way to boost your protein intake on Mounjaro, and may help to mitigate the effects of rapid weight loss on the muscles.

So now that we’ve covered the types of supplements you may want to add to your lifestyle, what vitamins should not be taken with Mounjaro? Let’s take a look. 

What Vitamins Should Not be Taken with Mounjaro?

While there are no known interactions between particular vitamins and Mounjaro, certain dietary supplements may increase your risk of side effects. For example, fibre can help to relieve some Mounjaro side effects, like constipation, but it can make others worse.

Clinicians recommend that people with diarrhoea, bloating, nausea, and vomiting temporarily reduce their intake of dietary fibre. Taking fibre supplements may prolong or even worsen these symptoms, so you should avoid them while experiencing gastrointestinal side effects on Mounjaro.

You may also need to avoid herbal remedies with the potential to lower blood glucose levels. This is because while blood sugar reduction is an intended effect of Mounjaro, it can increase your risk of hypoglycemia. Hypoglycemia (very low blood sugar) is more common among people using Mounjaro alongside other diabetes medications, like insulin or sulfonylureas. Fenugreek and bitter melon are two herbal supplements that also have hypoglycemic effects; therefore, they should not be taken with Mounjaro.

Other dietary supplements to exercise caution around are those containing cinnamon, chromium, or berberine. The benefits of these remedies for blood sugar control are not fully understood, but they are thought to lower blood glucose levels. Therefore, they may further increase your risk of hypoglycemia if taken with Mounjaro.

For How Long Should I Take Vitamins with Mounjaro?

There are no fixed guidelines on which vitamins to take on Mounjaro, or how long to take them for. Supplements that don’t exacerbate Mounjaro side effects may be used throughout treatment and could promote better health on your weight loss journey. However, you should avoid certain supplements (like fibre) when experiencing flare-ups of gastrointestinal symptoms.

If you have any questions regarding your diet, nutrition, or health on Mounjaro, reach out to our licensed clinicians. Only a healthcare professional can accurately assess your medical needs and advise you on the best course of action. Remember that everyone’s experience is completely different, so you have to take the best course of action for your circumstances. 

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• Approved Weight Loss Treatment
• Suitable for adults with a BMI of +30kg/m²
• Pre-filled injection pen

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• Online prescription - No doctor visit

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What Supplements Should I Take with Mounjaro: How to Find Out

Not everyone needs to take supplements with Mounjaro, but nutritional insufficiencies are common among people who rapidly reduce their food intake. The best way to find out for yourself what vitamins to take on Mounjaro is to understand what your deficiencies are (if any). This is done via a blood test.

A blood test can give a complete picture of your body’s nutritional status and highlight any deficiencies you may have. This allows you to make informed decisions about your diet and which supplements to take with Mounjaro.

You may need to schedule a blood test if:

• Your diet is nutritionally poor or lacking certain food groups
• Your food intake is severely restricted by Mounjaro treatment
• You experience gastrointestinal symptoms on Mounjaro
• You have symptoms of a nutritional deficiency

Mounjaro Medication Interactions

Certain medications can interact with tirzepatide, the active ingredient in Mounjaro. For example, drugs that lower blood sugar, like insulin and sulfonylureas, may increase your risk of hypoglycemia on Mounjaro. People who use anti-diabetic medications should bring these to the attention of their prescribing clinician before starting Mounjaro. You will need to monitor yourself closely for signs of hypoglycemia, and your doctor may advise a dose adjustment to mitigate this risk.

Mounjaro delays gastric emptying, and this effect can interfere with the absorption of oral medications and hinder their efficacy. For example, using Mounjaro can make oral contraceptives less effective, with the potential to result in unintended pregnancy. Therefore, women using oral contraceptives should use a non-oral form of contraception while on Mounjaro.

Mounjaro may render other oral medications, including antibiotics, painkillers, and warfarin, less effective. If you take any oral medications, discuss these with a licensed clinician before starting Mounjaro treatment.

Effective Weight Loss Support from Prescription Doctor 

Embarking on a weight loss journey can be a large undertaking that may seem daunting for some. If you’re thinking about exploring the potential benefits of Mounjaro but feel like you could do with some specialist support and guidance, Prescription Doctor is here for you.

We’ve made it our mission to take the hassle out of healthcare. With us, there’s just a simple procedure that offers you access to licensed medication from the comfort of your own home, no appointment required. Simply complete the medical questionnaire and our clinicians will review your information to determine whether Mounjaro is suitable for your circumstances. Once approved, your products will be dispatched in plain and discreet packaging. It’s that straightforward. Orders authorised before 3pm on a weekday also benefit from next-day delivery, giving you access to your treatment with minimal fuss.

Our holistic approach to healthcare means that our service doesn’t just stop once your medication has left the building. We offer comprehensive guidance on a wealth of subjects relating to Mounjaro. This ranges from the vitamins to take on Mounjaro, how to use the injection pen safely, exercise strategies, dosing guides, and much more besides.

In addition, our team of licensed clinicians will regularly check in with you to monitor progress and ensure everything is working as it should. We’re with you every step of the way.

Ready to get started? Sign up for a weight loss consultation today and let us help you towards reaching your goals. 

Authored By

Kate Latham

Medical Content Writer

Kate has been a scientific content writer since 2017. With a BSc in Biology and a background in cancer research, she is adept at identifying the latest findings in medical research and utilising these

Published on: 07/08/2025

Reviewed By

Mohamed Imran Lakhi

MPharm - Lead Pharmacist

Imran Lakhi is the superintendent pharmacist and founder at Prescription Doctor. He has been at the core of our team.

Reviewed on: 07/08/2025