Mysimba Reviews from Real Users
Deciding whether to add weight loss medication to your diet and exercise regimen is an important undertaking. This is why it’s a good idea to do as much research as possible about your chosen treatment, including how it works, how to administer it, and the potential side effects.
Another essential piece of information is how effective the medication is in helping you reach your goals. Although clinical trials can offer a good indication of this, seeing real-life accounts of how other users have found the treatment is invaluable.
Join us as we explore real Mysimba reviews from our customers that appear on our Trustpilot profile. We’ll discover how the treatment has impacted weight loss, side effects, and cravings, so you can make a more informed decision about whether the medication could be right for you.
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Is Mysimba Good for Weight Loss?
Mysimba is a good option for weight loss when taken alongside a healthy diet and regular exercise. Clinical trials have shown that it can help people lose around 8.1% of their body weight in 56 weeks. Between 13% and 22% of people lose up to 10% of their starting body weight, compared to around 5-6% with a placebo.
Since it comes in tablet form, Mysimba is a particularly good alternative to weight loss injections for those who have a phobia of needles. You may also want to switch to the treatment if you haven’t seen much progress with your current medication.
As with all weight loss treatments, the effectiveness of Mysimba depends on several factors. These include your starting weight, lifestyle choices, and how your body responds to the medication. Because it was initially licensed to combat addiction, Mysimba is extremely useful for people who struggle with cravings and emotional eating.
The Importance of Mysimba Reviews on Trustpilot
Gathering Mysimba reviews on Trustpilot helps share real-world user experiences, so you can understand how well the treatment reduces appetite and supports weight loss. It also offers insights into the medication’s benefits, such as fewer cravings and increased energy levels, while in turn providing an honest overview of side effects and how people manage them.
Here are some aspects of Mysimba treatment that Trustpilot reviews can be really useful for:
- Effectiveness: Many reviews give real-life insight into how Mysimba supports weight loss, with users sharing how much weight they have lost as well as highlighting the drug’s ability to reduce your appetite and minimise cravings.
- Common side effects: Several Mysimba users report side effects, particularly at the beginning of treatment, but they usually wear off or improve over time.
- Holistic benefits: Alongside weight loss, Mysimba users also share that the medication has helped to improve their mental well-being and self-esteem. Some also report that it can improve their mood or motivation, key factors in sticking to a weight loss diet plan.
- Long-term treatment: Some reviewers report regaining some weight after stopping treatment, but lifestyle changes, such as adopting a healthy diet and engaging in regular exercise, can help counteract this.
Mysimba Reviews UK: A Breakdown
The section below provides some real Mysimba reviews from UK-based Prescription Doctor customers. It offers valuable insights into how the medication supports weight loss, common side effects, and the importance of pairing the treatment with lifestyle changes that promote health and well-being.
In addition, the reviews highlight people’s experiences with our service, so you can understand what you can expect when you choose Prescription Doctor as your weight loss partner.
Mysimba Weight Loss Reviews
Many users report that the medication effectively reduces their appetite and aids in weight loss. Several mention losing weight within the first few weeks of use, feeling fuller quicker, and experiencing a decrease in cravings, particularly for sweets and unhealthy foods.
Some patients note immediate effects, while others say it's too early to tell or that they haven't noticed a significant change in appetite or weight.
“Wow, I really recommend these tablets. My appetite is very low, which is good, and I am losing weight. Slowly, but my weight is going down. I will order again because it helps me.”
Alexandra Mandikova
“Going good. Lost 4 lb in first week.”
Jacqueline Sutcliffe
“I have just started my prescription 4 days ago, and I can honestly say it is curbing my appetite and my thoughts about food. I’m hoping as I get into the weeks, it will continue to benefit me.”
Traci Morrow
These reviews align with clinical trials showing that Mysimba effectively reduced body weight more frequently than placebo. One study found that the average weight loss over 56 weeks was 5.4%, while others report losses of 8.1%. The studies required participants to engage in lifestyle modifications, emphasising that Mysimba is most effective when combined with diet and exercise changes.
Mysimba
- Reduces cravings & emotional eating
- Convenient, twice-daily oral treatment
- Proven weight loss results
Mysimba Side Effects Reviews
While many users do not report significant side effects, a few mention experiencing anxiety, headaches, nausea, and insomnia. One user stopped taking the medication due to its strength and the side effects experienced.
Side effects, however, are most likely when you first start Mysimba, but are often not severe enough to put people off continuing with the medication, while some people get no side effects at all.
“It’s good so far, week one, and I have some side effects: slight nausea and slight headaches, but not enough to need pain relief. It’s really helped me lose interest in food. I’m having my two meals a day, and that’s it :) I highly recommend, but I’ve only been on one tablet a day so far; about to move to two.”
Isabelle
“Seems to be working fine and no side effects.”
Tricia Mottram
“Very good product when you keep watching what you eat. In the first 4 weeks, I lost 6kg with minimal exercise. Side effects gone after 3rd day.”
Joanna Basik
Most Mysimba side effects can be managed at home with rest, hydration, and over-the-counter painkillers, and usually resolve within a few days to weeks. If you are finding it difficult to manage them, our clinicians are on hand to discuss your weight loss options, including switching to an alternative weight loss medication.
Mysimba
- Reduces cravings & emotional eating
- Convenient, twice-daily oral treatment
- Proven weight loss results
Mysimba Tablets Reviews: Lifestyle & Cravings
Several reviews highlight the importance of combining the medication with a healthy diet and exercise for optimal results. It's not seen as a 'magic pill' but rather as an aid alongside lifestyle changes.
Naltrexone and bupropion work by targeting two key brain regions that help regulate your appetite and the rewarding feeling you get when you eat. In doing so, Mysimba reduces your appetite and curbs cravings, helping you lose weight.
“Definitely reduced my appetite and the delivery was exceptionally quick!”
Amber Watters
“Seems to have a mild appetite suppressing effect, not much in the way of side effects of note so far, definitely not a magic pill but useful along with careful diet and exercise.”
Jason Reid
“Mysimba reduced my feeling of hunger, and I’m still in the first week.”
Rihab Halloum
By reducing hunger and appetite, Mysimba can make weight loss easier than dieting alone. It’s important to remember that Mysimba is not an overnight solution and requires effort and adherence to lifestyle changes for the best results.
Mysimba
- Reduces cravings & emotional eating
- Convenient, twice-daily oral treatment
- Proven weight loss results
Prescription Doctor Mysimba Reviews
Selecting Mysimba is just one part of your weight loss journey. For success, you need to choose a partner that will support you along the way, with clinicians available to give advice and help you overcome any potential obstacles. At Prescription Doctor, we are proud of the service we provide our patients to ensure they receive the support they need.
Our service is frequently praised for its quick and efficient service, with many patients appreciating its fast delivery and easy purchase process. Most users are satisfied with the product and service, with several planning to continue using the medication or recommending it to others.
“I find Mysimba has really helped me stay on track with my healthy eating. It does not lower your appetite; it takes the craving away in your brain. So if you’re a chocoholic or a binge eater, this would be very helpful. You would have to follow a diet programme of healthy eating alongside these pills. I’ve tried every diet on the market, but my cravings have always let me down. I feel very safe using Prescription Doctor online; they have a good helpline if I need any extra information.”
Anonymous
“Very helpful doctor and customer service. Very quick delivery. I will be using it in the future.”
Maria Huertas
“Excellent professional service!!”
Zoe
Access to a responsible and encouraging service whose clinicians can provide clear guidance and advice when you’re taking Mysimba. That’s why many people have chosen to partner with Prescription Doctor for their weight loss journey.
Mysimba
- Reduces cravings & emotional eating
- Convenient, twice-daily oral treatment
- Proven weight loss results
A Library of Useful Information
These real Mysimba reviews can give you a valuable insight into how effective it can be and how it may help you, but you might now be looking for a deeper understanding of how it works and what to expect when you start treatment.
If you’d like to get a better idea of how naltrexone and bupropion work to suppress your appetite, our ‘How does Mysimba work?’ article breaks down how they act on neurotransmitters, such as dopamine and noradrenaline, to leave you feeling less hungry.
If you’re new to weight loss medication, you can learn how to take Mysimba effectively and how long it takes to work in our dedicated guides.
One of the hottest topics surrounding weight loss medications is their potential side effects, and our dedicated guide can give you a greater understanding of Mysimba’s side effects, like nausea and headaches, and how long they may last. If you’re undecided about whether Mysimba is right for you, we compare Mysimba vs. Saxenda to help you make an informed decision.
Whether you’re looking for further guidance to help you harness the full benefits of Mysimba or are still weighing up your options, our expanding library can provide clarity, reassurance, and confidence throughout your weight loss journey.
Dedicated Weight Loss Support from Prescription Doctor
If you’re thinking about embarking on a medicated weight loss programme, Prescription Doctor is here to help. We’ve supported countless individuals in achieving their goals, and we’re ready to do the same for you.
Our service is built entirely around your requirements. With us, you can start a consultation at any time from the comfort of your own home. Our specialist clinicians will then review your information to determine whether your chosen treatment is suitable for you or, if not, offer an alternative. Orders approved before 3pm on a weekday are also eligible for next-day delivery. It’s that straightforward.
After you’ve started treatment, our team will regularly check in with you to monitor progress and ensure everything is working successfully. You can also contact us whenever you have a query or require a bit more information. We are here for you.
Ready to get started? Begin a Mysimba consultation with Prescription Doctor today.
Sources
- eClinical Medicine (2022): The relationship between early weight loss and weight loss maintenance with naltrexone-bupropion therapy.
- EMC (2023): Mysimba 8 mg/90 mg prolonged-release tablets.
- European Medicines Agency (2025): Mysimba.
- Pharmacological Research (2014): Naltrexone/bupropion for obesity: An investigational combination pharmacotherapy for weight loss.
Authored By
Leanne Edermaniger
Medical Content WriterPublished on: 11/01/2023 Re-Published on: 08/01/2026
Reviewed By
Mohamed Imran Lakhi
MPharm - Lead PharmacistReviewed on: 08/01/2026
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