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Colchicine
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Treatment Information
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Table of contents
Colchicine and Gout Management
Colchicine is a medication specifically used to treat and prevent gout attacks. Gout is characterised by sudden, severe attacks of pain, redness, and tenderness in joints, often at the base of the big toe. Colchicine helps by reducing inflammation and alleviating these symptoms.
Dosage for Gout Attacks
- Normal Dose: For treating a gout attack, the usual dose is 500 micrograms of Colchicine taken 2 to 4 times a day.
- Maximum Limit: The total dose should not exceed 6mg (12 x 500 micrograms tablets) during a single gout attack.
- Special Considerations: If you are older or have liver or kidney problems, your dose may be adjusted accordingly.
Dosage for Preventing Gout Attacks
- Regular Dose: To prevent gout attacks, the typical dose is 500 micrograms once or twice daily.
- Adjustments for Health Conditions: This dose may be reduced if you have liver or kidney issues.
Consultation and Adjustments
- Seeking Higher Doses: If you're taking the maximum safe dose of Colchicine and still not finding relief, it's important to consult with a doctor. They can review your situation and may suggest alternative treatments.
- Concerns About Dosage: If you're unsure about your Colchicine dosage or worried about side effects, a discussion with a healthcare professional is crucial. They can determine if a lower dose is needed or if another treatment would be more appropriate.
Safe Use of Colchicine
While Colchicine is effective in managing gout, it's important to use it as directed. Do not exceed the recommended dosage, and always consider your personal health factors, such as age and any liver or kidney conditions.
Frequently Asked Questions (FAQs) About Colchicine
What should I know before taking Colchicine?
Do not take Colchicine if you are allergic to it or any of its ingredients, have a severe blood disorder, are pregnant or breastfeeding, or have severe kidney or liver problems. Also, avoid taking it if you are undergoing hemodialysis or if you have kidney or liver problems and are taking certain other medicines.
How should I take Colchicine?
Always take Colchicine exactly as prescribed by your doctor. The tablets should be swallowed whole with water. The dose for treating a gout attack is usually one Colchicine Tablet, followed by another tablet after 1 hour. For preventing flare-ups, the typical dose is one tablet twice daily. Dosage adjustments may be needed for those with kidney or liver problems.
What are the possible side effects of Colchicine?
Common side effects include nausea, vomiting, stomach pain, and diarrhea. Serious side effects may include symptoms such as fever, mouth inflammation, sore throat, prolonged bleeding, bruising, or skin problems, which could indicate serious blood problems due to bone marrow depression. Other side effects may include nerve inflammation, liver damage, hair loss, muscle pain or weakness, and kidney damage.
Can I take Colchicine during pregnancy and breastfeeding?
Colchicine should not be taken if you are pregnant, planning to have a baby, or breastfeeding. Women of childbearing potential should use effective contraception while taking Colchicine.
Can Colchicine affect my ability to drive or use machines?
Colchicine may cause drowsiness and dizziness. If you are affected, do not drive or operate machinery.
What should I do if I take more Colchicine than I should?
If you take more Colchicine than prescribed, contact your doctor or nearest hospital emergency department immediately. Symptoms of overdose may include nausea, vomiting, stomach pain, bloody diarrhea, and low blood pressure.
Additional Resource
Sources
NHS, 2023. Colchicine: NHS Medicine Guide.
EMC, 2023. Colchicine: EMC Patient Information Leaflet.
NHS, 2023. About Colchicine: NHS Medicine Guide.
NHS, 2023. Gout: NHS Condition Guide.
West Essex CCG, 2023. Gout Guidelines: West Essex CCG.
NICE CKS, 2023. Gout - Prescribing Information: Colchicine.
NCBI, 2023. Colchicine - NCBI Bookshelf.
NICE CKS, 2023. Management of Acute Gout: NICE CKS.
BNF, 2023. Colchicine: BNF Drug Information.
Treatment information
- Product Name: Colchicine
- Manufacturer: Varies
- Active Ingredient(s): Colchicine
- Administration: Oral
- Presentation: Tablets
- Available Strength: 500mcg
- Exemption:
- Dosage: Attacks 500 micrograms 2 to 4 times a day, not exceeding 6mg (12 x 500 micrograms tablets) during one outbreak.
- Description: Colchicine is used to treat and prevent gout attacks. It works by reducing inflammation and pain associated with gout. It is not a cure for gout but helps manage the symptoms.
- Drug Class: Anti-gout medication
- Alcohol Consumption: Consult a healthcare provider for specific advice
- When Pregnant: Consult a healthcare provider for specific advice
- Price: GBP
Click here to view the Colchicine - Patient Information Leaflet
Authored By
Melissa Keen
Medical Content Writer
Melissa is a medical content writer specialising in health and wellness, distinguished by her work with leading UK health brands.
Published on: 07/11/2023
Published on: 07/11/2023
Reviewed By
Dr Giuseppe Aragona
Doctor
Dr. Giuseppe utilises his extensive experience in general practice to ensure the accuracy and safety of the website's content.
Reviewed on: 13/03/2024
Reviewed on: 13/03/2024
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