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About Product
Mohamed Imran Lakhi
This content has been written and checked for quality and accuracy by
Mohamed Imran Lakhi Content Administrator GPhC: 2060586 Updated on: 26/05/2020 Next review: 26/11/2020

What is Trisequens?

Trisequens are tablets used in hormone replacement therapy to treat the symptoms of the menopause. They are arranged in a cyclical calendar pack.

Trisequens contains two synthetic hormones, known as estradiol and norethisterone, which mimic the natural sex hormones in the female body, respectively named oestrogen and progesterone.

What is menopause?

Later in a woman’s life, her body undergoes a number of hormonal changes. Levels of female sex hormone oestrogen drop, causing a hormonal imbalance which affects the reproductive system. Ovulation (the releasing of an egg from the ovaries) slows down before ceasing completely. As do the regular menstrual cycles (periods).

The menopause typically starts between the ages of 45 and 55, with symptoms usually lasting for around 4 years.

What are the symptoms of the menopause?

Common symptoms of the menopause include:

  • Hot flushes
  • Night Sweats
  • Vaginal dryness
  • Difficulty sleeping
  • Mood swings
  • Change in sex drive
  • Difficulty concentrating

While many women have no problems with the attributed symptoms of the menopause, some women may find that their symptoms interfere with their lifestyle or well-being. For these women, A hormone replacement treatment can be prescribed to rebalance the hormones in the body and relieve the unpleasant symptoms.

How to take Trisequens?

Always take medicine as prescribed by your doctor.

Trisequens should be taken every day. Take the tablets at the same time each day to remember when to take them.

What should I do if I forget to take a dose of Trisequens?

If you forget a dose, take the forgotten dose as soon as you remember.

If you forget a dose and it is near the time of your next dose, skip the missed tablet and take your next dose as you normally would.

What are the side effects of Trisequens?

All medicine carries the risk of side effects, though not everyone will experience them. It’s important to familiarise yourself with the risks associated with your medication by reading the patient information leaflet enclosed with your treatment.

Possible side effects of Trisequens may include:

  • Breast tenderness or pain
  • Irregular periods or excessive bleeding during periods
  • Headache
  • Weight changes caused by fluid retention
  • Inflammation of the vagina
  • Fungal infection in the vagina
  • New or worsened migraine
  • New or worsened depression
  • Nausea
  • Abdominal pain
  • Swelling of the breasts
  • Back pain
  • Leg cramps
  • Benign tumour of the womb (Uterine fibroid)
  • Swelling of arms and legs

If you experience any side effects, speak to your doctor or a pharmacist.

If you believe you experience an allergic reaction to the use of this medicine, stop taking trisequens and seek immediate medical attention.

For more information about the possible side effects associated with this medication, as well as dosing and storage instructions, please consult the patient information leaflet enclosed with the medicine.

Trisequens are not a form of hormonal contraception. If you become pregnant while taking trisequens, speak to your doctor as soon as possible.

Do not take trisequens if you are pregnant or breastfeeding.

Table of contents

What is Trisequens?

What is menopause?

How to take Trisequens?

What are the side effects of Trisequens?

Treatment information

  • Product Name: Trisequens
  • Manufacturer: Novo Nordisk
  • Active Ingredient(s): Estradiol and norethisterone
  • Administration: Oral
  • Presentation: Tablets
  • Exemption: Prescription Only
  • Application: Women going through the menopause
  • Dosage:As prescribed by the doctor
  • Description: Hormone replacement therapy to treat the symptoms of the menopuase
  • Drug Class: Hormone replacement therapy (HRT)
  • Alcohol Consumption: No influence
  • When Pregnant: Do not take Trisequens
  • When Breastfeeding: Do not take Trisequens
Click here to view the Trisequens - Patient Information Leaflet

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