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How Much Sandrena Gel Should I Use?

Considering Sandrena gel for your menopause symptoms like hot flushes? This HRT contains the active ingredient estradiol.

This article will clarify the correct dosage of Sandrena gel to use for effective treatment and minimal side effects. So, what is the right amount of Sandrena gel for you? Let's find out.

Optimal Usage of Sandrena Gel

How much Sandrena gel you should use depends on your prescription . You are likely to start at the lowest dose of 0.5 mg, which your doctor can increase to 1.0 mg. The maximum dose per day of Sandrena gel is 1.5 mg.

There are 2 sachet options available for Sandrena gel:

  • 0.5 mg (0.5 g sachet) or;
  • 1 mg (1 g sachet)

How Can a 1.5 mg Daily Dose be Achieved with Sandrena Gel?

You can make a daily dose of 1.5 mg of Sandrena gel in 2 ways:

  • a 1 g sachet and a 0.5 g sachet
  • 3 x 0.5 g sachets

Can You Use Too Much Sandrena Gel?

It’s unlikely to overdose on Sandrena gel, as you can wash it off. Speak to your doctor or pharmacist if you use more than you should.

Exceeding the prescribed dosage of Sandrena gel can lead to a range of adverse symptoms, including bloating, irritability/anxiety, tender breasts, nausea or vomiting, and withdrawal bleeding.

Missed Dose of Sandrena Gel

If you miss a dose of Sandrena gel, you can:

Missing a dose may cause breakthrough bleeding, like a period.

Dosage Specifics

0.5 mg of Sandrena gel may be enough to ease your symptoms and your doctor will always try to give you the lowest dose possible to reduce side effects. If you don’t think your dose is high enough or your symptoms are not getting better after a few weeks, speak to your doctor.

When is the Best Time to Use Sandrena Gel?

You can use Sandrena gel any time, but try to stick to the same time each day .

How Much Sandrena is Equivalent to Oestrogel?

1.5 mg of Sandrena gel is equal to 2 pumps of Oestrogel.

Other Considerations

Pregnant or breastfeeding women should not use Sandrena gel. Certain medical conditions may return or become worse, so tell your doctor if you have been diagnosed with anything, or are currently getting a diagnosis.

Some medications may affect how Sandrena gel works, or vice versa, so your doctor may reduce your dose if you take certain medications.

You can use HRT at any age, but only if you have been through menopause.


How much Sandrena gel you should use depends on what you’ve been prescribed to manage your symptoms. This may change if you take certain medications or have another medical condition. You’ll usually be prescribed the lowest dose of 0.5 mg, which can be increased if necessary.

If you have menopause symptoms that are impacting your life, speak to your doctor or one of our prescribers about a personalised HRT plan. You can also find out more information on HRT treatments or Sandrena gel on our website.

Authored & Reviewed By

Mohamed Imran Lakhi

MPharm - Lead Pharmacist
Imran Lakhi is the superintendent pharmacist and founder at Prescription Doctor. He has been at the core of our team.

Published on: 19/09/2023 Reviewed on: 01/11/2023
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