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How to order
  1. Click on the green "Back To Get Started" button, then click "Start Consultation" button on the next page.
  2. Fill in our short consultation form.
  3. Choose delivery method and mode of payment.
  4. Our team of expert prescribers will assess whether medication is suitable.
  5. If you get the green light and it is deemed suitable, your order will be processed quickly and efficiently.
Confidential Service

Your privacy is important, Prescription Doctor are committed to keeping your details completely confidential.

This is why we also take steps to conceal your prescription products under two layers of packaging.

Delivery and Packing
Discreet Delivery?

We have a commitment to delivering a discreet service and understand your need for privacy. We ship all orders via a trackable courier using discreet, plain packaging.

Do I Need to Wait in All Day for Delivery?

Once your order is dispatched you will receive a tracking number via sms and email.

Do You Deliver on Weekends?

We deliver medications between Monday and Saturday. You can upgrade to Saturday delivery on Friday.

My Order Hasn’t Arrived What Should I Do?

You should receive a tracking number with your order which you can use this number to track your parcel online. This should give you a clear indication of where your parcel is. If you haven’t received your parcel in the time frame given by our couriers, contact your local depot to find out where it is. You can also contact our support team who will do this for you.

Can I Be Notified by Text?

On checkout you will be asked to leave your mobile number so our courier can text you about the delivery. This is also useful if the courier has problems finding your address. We will not use your mobile number for anything else.

Payment Methods
How Can I Pay for My Order?

You can pay for your order using credit, debit card or via bank transfer.

I Don’t Have a Credit Card, How Can I Pay?

If you don’t have a credit or debit card you can pay via bank transfer. We will give you a unique reference number at checkout along with details of how to make the transfer. Once the money has cleared in our account, we will process your order.

How Do You Keep My Details Safe?

We are a completely secure site and take many measures to ensure your details are kept safe. We understand that you have a right to extreme privacy when purchasing sensitive health medications. All information that you provide to us is stored on our secure servers. Any payment transactions will be encrypted using SSL technology.

Payment and refunds?

You can pay for your order using credit, debit card and bank transfer.

Card Payment: Please notify us that you wish to cancel your order. Your refund will show available In 1 - 3 days.

Bank Transfer: A member of our team will contact you requesting for your bank details. These details are only used to transfer the funds back into your account.

Treatment Information

Table of contents

What is Sandrena Gel?

Sandrena Gel is a topical Hormone Replacement Therapy (HRT) designed to treat menopause symptoms by replenishing declining oestrogen levels.

It replaces the levels of oestrogen that decrease during menopause.

Available in two strengths: 0.5mg and 1.0mg of estradiol. Each pack contains 28 sachets.

Understanding Menopause Before Treating With Sandrena Gel

Understanding menopause is crucial before starting any treatment. It is a natural phase that ends fertility and menstruation, usually occurring between ages 40 and 50.

Menopause is an inevitable phase for women, signalling the end of menstruation and fertility.

Premature menopause can occur due to surgical removal of the womb (hysterectomy) or ovarian failure.

In the UK, menopause symptoms last for an average of 4 years, but can range between 2 to 10 years.

Symptoms and Causes:

  • A decline in the female sex hormone oestrogen causes menopausal symptoms.
  • Common Symptoms Include:
  • Decreased muscle mass
  • Flushing
  • Headaches
  • Recurrent UTIs
  • Vaginal dryness
  • And more...

Sandrena Gel Treatment Options:

Sandrena Gel replenishes the body with estradiol, a form of oestrogen. Consult your doctor for appropriate treatment options, including HRT.

  • Sandrena Gel replenishes the body with an oestrogen called estradiol.
  • There are tests like the SELF Check Menopause Test to confirm menopause.
  • Your doctor can discuss Hormone Replacement Therapies (HRT) to treat symptoms.
  • A doctor may also prescribe a progestogen alongside an oestrogen to reduce risks like endometrial hyperplasia or endometrial cancer.

How Do I Use Sandrena Gel?

Sandrena Gel is applied directly to the skin of the lower body, such as the thighs.

The active ingredient, estradiol, is absorbed through the skin.

You should apply the gel on alternating sides of your body.

Rub the gel into your skin, ensuring to spread it evenly, and allow the area to dry.

Always wash your hands after applying the gel.

Sandrena Gel Side Effects and Cautions

Before using Sandrena gel, you must carefully read the patient information leaflet. This leaflet contains instructions on how to store and use the gel, as well as important information regarding the safety of Sandrena gel.

If you have any questions or concerns about any of the information presented in the patient information leaflet, feel free to discuss them with our online prescriber by using the “my chats” feature under your Prescription Doctor account.

Who should not use Sandrena Gel?

Sandrena is not suitable for everyone. If you are not sure whether Sandrena is suitable for you, consult your doctor.

Do not use Sandrena if you:

  • have or have ever had breast cancer
  • have cancer that is sensitive to oestrogens, such as endometrial cancer (cancer of the womb)
  • have any unexplained vaginal bleeding
  • have untreated endometrial hyperplasia
  • have or have ever had a blood clot in the vein (thrombosis)
  • have a blood clotting disorder
  • have or recently have had a disease relating to blood clots in the arteries (e.g. heart attack, stroke or angina)
  • have or have ever had liver disease or abnormal liver function test results that have not returned to normal
  • have a rare blood disorder called porphyria
  • are allergic to estradiol or any of the other ingredients listed in the patient information leaflet

If you notice any of the above conditions occurring while taking Sandrena, stop using it and speak to your doctor immediately.

Side Effects

All medicines carry the risk of side effects, though not everybody gets them.

It’s important to familiarise yourself with the side effects listed in the patient information leaflet and to remain vigilant of any side effects.

Common side effects may include:

  • bleeding or spotting
  • breast pain or tenderness
  • changes in mood (including depression, nervousness or lethargy)
  • changes in weight
  • dizziness
  • flatulence
  • headache
  • hot flushes
  • itching of the skin, rash, pain, increased sweating, swollen feet and lower legs
  • nausea
  • stomach ache
  • vomiting

This is not a full list of side effects associated with Sandrena gel. A complete list of side effects can be found within the provided patient information leaflet enclosed with the medicine.

If you experience any side effects, regardless of whether they are listed above or in the patient information leaflet, inform your doctor as soon as you can.

Sandrena Gel Allergies

Do not use Sandrena if you are allergic to estradiol or any of the other ingredients listed in the patient information leaflet.

If you experience an allergic reaction after using Sandrena gel:

  • Stop using the product
  • Speak to your doctor

In the case of severe allergic reaction, such as anaphylaxis, go straight to your nearest accident and emergency department. Remember to take the packaging and any remaining sachets with you so that doctors treating you know exactly what you took.

Sandrena Gel During Pregnancy and Breastfeeding

Do not use Sandrena if you are pregnant or breastfeeding.

If you become pregnant while using Sandrena, stop using the gel immediately and consult your doctor.

Sandrena is not a contraceptive. If fewer than 12 months have elapsed since your last period, or you are under 50 years old, you may still become pregnant. You may still need to use contraception such as condoms to prevent pregnancy.

Other safety information

Inform our online prescriber of all other medicines you are currently using, including medicines prescribed by your doctor, or bought over the counter, as well as any health and herbal supplements you are taking.

Never use Sandrena Gel past the expiry date printed on the packaging.

Always store Sandrena gel out of sight and reach from children and pets.

Store Sandrena gel sachets in the original packaging. They should be stored at room temperature.

Do not store Sandrena about 25°C.

Never throw away medicine via household or water waste. Take any unwanted or expired medicine to your local pharmacy and ask them to dispose of it safely on your behalf. These measures can help to protect the environment.

Where Can I Buy Sandrena Gel Sachets Online?

At Prescription Doctor, we make the process of obtaining Sandrena Gel Sachets straightforward and secure. You can place an order online from a GPhC-registered pharmacy, ensuring that you're receiving a genuine and quality-assured product.

If you complete your order before 3pm on a weekday, our dedicated pharmacy team will dispatch it the very same day, offering you the convenience of next-day delivery. This ensures that you can start or continue your hormone replacement therapy without any unnecessary delays.

Frequently Asked Questions About Sandrena Gel

Will Sandrena Impact My Ability to Drive?

No studies have been conducted on whether Sandrena gel will impact your ability to drive or operate machinery.

If you experience any side effects which impair your cognitive ability, such as drowsiness or dizziness, do not drive or operate machinery until you feel better.

Can I Drink Alcohol While Using Sandrena Gel?

It is safe to drink alcohol while using Sandrena gel. Avoid drinking more than 14 units of alcohol per week, as per the government’s guidelines.

What Should I Do If I Forget to Use Sandrena Gel?

If you forget to use Sandrena gel when you should, apply the missed dose when you remember unless 12 hours have elapsed since your missed dose.

If it has been more than 12 hours since your last dose, skip the missed dose and continue to use Sandrena as you normally would.

Do not use more Sandrena gel to make up for the missed dose.

What Should I Do If I Use More Sandrena Gel?

If you accidentally apply more Sandrena gel than you should, speak to your doctor or a pharmacist.

Using too much Sandrena gel may increase your risk of side effects.

Does Sandrena Gel Cause Cancer?

Sandrena gel, like other oestrogen-based HRTS, may put you at an elevated risk of cancer of the womb or breast cancer. You should discuss your risk of cancer with your doctor.

You can find further information about the risk of cancer associated with HRTs within the patient information leaflet.

Do I Need a Prescription to Buy Sandrena Gel Online?

While we have online prescribers who can issue a private prescription for Sandrena gel, it is important to speak to your doctor before you begin hormone replacement therapy. Your doctor may need to conduct further assessments in person.

How Should I Store Sandrena Gel?

Store Sandrena gel at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets.

Can I Use Sandrena Gel During Pregnancy or Breastfeeding?

Sandrena gel is not recommended for use during pregnancy or breastfeeding. If you are pregnant, planning to become pregnant, or are breastfeeding, consult your doctor before using this medication.

Are There Any Foods or Medications That Interact With Sandrena Gel?

Some medications and foods may interact with Sandrena gel. It's important to inform your doctor about all medications, vitamins, and herbal supplements you are taking. Avoid grapefruit and grapefruit juice, as they may interact with the medication.

Can Men Use Sandrena Gel?

Sandrena gel is primarily formulated for women undergoing hormone replacement therapy. It is not recommended for men unless prescribed by a healthcare provider for specific medical conditions.

Treatment information

  • Product Name: Sandrena
  • Manufacturer: Orion Pharma Limited
  • Active Ingredient(s): Estradiol
  • Administration: Topical
  • Presentation: Gel
  • Available Strength: 0.5mg, 0.1mg
  • Exemption: Prescription Only
  • Dosage: Apply the gel once a day to the skin on your lower body or thighs.
  • Description: Sandrena gel is a topical HRT menopause treatment
  • Drug Class: Hormonal replacement therapy (HRT)
  • Alcohol Consumption: No influence
  • When Pregnant: Do not use while pregnant. Speak to your doctor for further information.
  • When Breastfeeding: Do not use while breastfeeding. Speak to your doctor for further information.
  • Related Drug: Oestrogel
  • Price: 24.99 GBP
Click here to view the Sandrena - Patient Information Leaflet

Authored & Reviewed By

Mohamed Imran Lakhi

Mohamed Imran Lakhi

MPharm - Lead Pharmacist
Imran Lakhi is the superintendent pharmacist and founder at Prescription Doctor. He has been at the core of our team.

Published on: 27/05/2022 Reviewed on: 13/03/2024

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