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This is why we also take steps to conceal your prescription products under two layers of packaging.

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We have a commitment to delivering a discreet service and understand your need for privacy. We ship all orders via a trackable courier using discreet, plain packaging.

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We deliver medications between Monday and Saturday. You can upgrade to Saturday delivery on Friday.

My Order Hasn’t Arrived What Should I Do?

You should receive a tracking number with your order which you can use this number to track your parcel online. This should give you a clear indication of where your parcel is. If you haven’t received your parcel in the time frame given by our couriers, contact your local depot to find out where it is. You can also contact our support team who will do this for you.

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If you don’t have a credit or debit card you can pay via bank transfer. We will give you a unique reference number at checkout along with details of how to make the transfer. Once the money has cleared in our account, we will process your order.

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You can pay for your order using credit, debit card and bank transfer.

Card Payment: Please notify us that you wish to cancel your order. Your refund will show available In 1 - 3 days.

Bank Transfer: A member of our team will contact you requesting for your bank details. These details are only used to transfer the funds back into your account.

About Product
Mohamed Imran Lakhi
This content has been written and checked for quality and accuracy by
Mohamed Imran Lakhi Content Administrator GPhC: 2060586 Updated on: 26/05/2020 Next review: 26/11/2020

What is Kliofem?

Kliofem is a continuous, combined hormone replacement therapy treatment (HRT) for postmenopausal women. It contains two synthetic hormones called estradiol and norethisterone, which are similar to the natural sex hormone oestrogen and progesterone respectively.

Together, the synthetic hormones correct the hormonal imbalance in the woman’s body. The estradiol supplements the falling levels of the hormone oestrogen while the norethisterone counteracts the effect of the estradiol, preventing the endometrium from growing excessively.

What is the menopause?

The menopause is the time in a woman’s life when her body stops preparing itself for pregnancy. Menstruation cycles and ovulation with both slow down before stopping completely.

During the menopause, oestrogen levels in the body fall which cause a number of symptoms such as:

  • Difficulty sleeping
  • Hot flushes
  • Lower sex drive (libido)
  • Mood swings
  • Night Sweats
  • Vaginal dryness

Typically, these symptoms begin between the ages of 45 and 55, with many women experiencing symptoms around the age of 51, according to the NHS. If a woman particularly suffers from these symptoms, HRT can be prescribed to balance the hormones in the body.

How to take Kliofem?

Always follow the dosage prescribed by a healthcare professional.

Kliofem can be taken with or without food. Swallow the tablets whole with a glass of water.

Kliofem should be taken once daily at the same time each day.

What should I do if I forget to take Kliofem when I should?

If you miss a dose, take it as soon as you remember.

If you miss a dose and it has been 12 hours since your last dose, or if it is nearly time for your next dose, skip the missed tablet and take the next tablet as normal.

Do not take more than the prescribed dose of Kliofem. If you accidentally take more Kliofem than prescribed, seek immediate medical attention.

Side effects and cautions of Kliofem

All medications carry the risk of side effects, though not everyone experiences them. Before taking your medication, it is important to familiarise yourself with the possible risks associated with your treatment by reading the patient information leaflet. This document can be found enclosed in your treatment.

Possible side effects of Kliofem may include:

  • Breast pain or tenderness
  • Changes in sex drive (libido)
  • Dizziness
  • Fluid retention
  • Gallbladder disease
  • Headaches or migraine
  • Increased risk of blood clots
  • Indigestion
  • Inflammation of the pancreas (pancreatitis)
  • Menstrual bleeding or spotting
  • Mood swings
  • Nausea
  • Tiredness
  • Vaginal thrush
  • Weight changes

Who should not use Kliofem?

Kliofem should not be used by women who:

  • Had a disease caused by a blood clot in the past such as a heart attack, stroke or angina
  • Have a blood clotting disorder
  • Have a rare blood condition called porphyria (inherited)
  • Have any unexplained vaginal bleeding
  • Have excessive thickness of the endometrium (endometrial hyperplasia)
  • Have or had any blood clots in the veins (deep vein thrombosis or pulmonary embolism)
  • Have or had liver disease
  • Have, had or suspect they have breast cancer
  • Have, had, or suspected cancer of the womb lining (endometrial cancer)

Kliofem should not be used by women who are pregnant or breastfeeding. If you discover you are pregnant while taking Kliofem, stop treatment immediately and consult a doctor.

Kliofem is not a form of contraception. If it is has been less than 12 months since your last period or you are under the age of 50, you may need to use additional contraception to prevent pregnancy.

Do not take Kliofem if you are allergic to any of the ingredients.

Staying safe with Prescription Doctor

In order for our doctors to issue a prescription, you will need to fill out a short medical form so that our prescribers can determine whether the treatment you requested is right for you.

If the doctor approves your order, a prescription will be issued and sent to our dispensing pharmacy who will process your order.

If your order is processed before 3 pm, it will be dispatched in discreet packaging for next-day tracked delivery.

Table of content

What is Kliofem?

What is menopause?

How to take?

Side effects and cautions

Staying safe with Prescription Doctor

Additional resources

10 questions about the menopause answered

Treatment information

  • Product Name: Kliofem
  • Manufacturer: Novo Nordisk
  • Active Ingredient(s): Estradiol and Norethisterone
  • Administration: Oral
  • Presentation: Tablets
  • Available Strength: 2 mg Estradiol, 1 mg Norethisterone
  • Exemption: Prescription Only
  • Application: Postmenopausal women
  • Dosage: Take one tablet daily
  • Description: Kliofem is a continuous combined HRT for postmenopausal women
  • Drug Class: Hormones replacement therapy (HRT)
  • Alcohol Consumption: No influence
  • When Pregnant: Do not take Kliofem
  • When Breastfeeding: Do not take Kliofem
Click here to view the Kliofem - Patient Information Leaflet

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