results found...


In Stock

Prices from £34.99
Review More Prices

Start Order
You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you.
How to order
  1. Click on the green "Start Order" button.
  2. Fill in our short consultation form.
  3. Choose delivery method and mode of payment.
  4. Our team of expert prescribers will assess whether medication is suitable.
  5. If you get the green light and it is deemed suitable, your order will be processed quickly and efficiently.
Confidential Service

Your privacy is important, Prescription Doctor are committed to keeping your details completely confidential.

This is why we also take steps to conceal your prescription products under two layers of packaging.

Delivery and Packing
Discreet Delivery?

We have a commitment to delivering a discreet service and understand your need for privacy. We ship all orders via a trackable courier using discreet, plain packaging.

Do I Need to Wait in All Day for Delivery?

Once your order is dispatched you will receive a tracking number via sms and email.

Do You Deliver on Weekends?

We deliver medications between Monday and Saturday. You can upgrade to Saturday delivery on Friday.

My Order Hasn’t Arrived What Should I Do?

You should receive a tracking number with your order which you can use this number to track your parcel online. This should give you a clear indication of where your parcel is. If you haven’t received your parcel in the time frame given by our couriers, contact your local depot to find out where it is. You can also contact our support team who will do this for you.

Can I Be Notified by Text?

On checkout you will be asked to leave your mobile number so our courier can text you about the delivery. This is also useful if the courier has problems finding your address. We will not use your mobile number for anything else.

Payment Methods
How Can I Pay for My Order?

You can pay for your order using credit, debit card or via bank transfer.

I Don’t Have a Credit Card, How Can I Pay?

If you don’t have a credit or debit card you can pay via bank transfer. We will give you a unique reference number at checkout along with details of how to make the transfer. Once the money has cleared in our account, we will process your order.

How Do You Keep My Details Safe?

We are a completely secure site and take many measures to ensure your details are kept safe. We understand that you have a right to extreme privacy when purchasing sensitive health medications. All information that you provide to us is stored on our secure servers. Any payment transactions will be encrypted using SSL technology.

Payment and refunds?

You can pay for your order using credit, debit card and bank transfer.

Card Payment: Please notify us that you wish to cancel your order. Your refund will show available In 1 - 3 days.

Bank Transfer: A member of our team will contact you requesting for your bank details. These details are only used to transfer the funds back into your account.

About Product
Mohamed Imran Lakhi
This content has been written and checked for quality and accuracy by
Mohamed Imran Lakhi Content Administrator GPhC: 2060586 Updated on: 26/05/2020 Next review: 26/11/2020

What is Kliovance?

Kliovance contains two synthetic hormones - estradiol and norethisterone - which mimic the natural sex hormones oestrogen and progesterone. The medicine is used in hormone replacement therapy (HRT) for postmenopausal women who have not undergone a hysterectomy (an operation to remove the womb).

During the menopause, the levels of oestrogen in a woman’s body gradually diminishes, which can cause various undesired effects such as hot flushes, night sweats, vaginal dryness, sleep disturbances, mood swings and changes in sex drive (libido). For some women, these symptoms can interfere with their lifestyle and well-being. If this is the case, HRT can be prescribed to balance out the hormones in the body and relieve the unwanted symptoms.

The two active ingredients of Kliovance work together to return hormonal balance. Estradiol supplements the oestrogen deficiency brought on by the menopause, however an increase of oestrogen in the body can cause excessive growth of the endometrium (lining of the womb).

Norethisterone regulates the growth of the endometrium to reduce the risk of developing cancer of the womb.

Postmenopausal women are at a greater risk of developing fragile bones (osteoporosis). Kliovance has been shown to preserve bone minerals to prevent osteoporosis from occurring. Before taking Kliovance, you should consult your doctor about all the available treatments for your symptoms.

How to take Kliovance?

Always take your medicine as prescribed by the doctor.

Kliovance comes packaged in a calendar pack. This makes it easy to remember when to take the tablets. The patient information leaflet enclosed with your medicine provides instructions on how to use this.

Kliovance can be taken with or without food. Swallow each tablet whole with water. Do not crush or chew the tablets.

The typical dose for the treatment of the menopause is one tablet daily. Take the tablet at the same time each day so that you always remember.

If you miss a dose of Kliovance, take it as soon as you remember.

If it has been 12 hours since you forgot, or if it near the time of your next dose, skip the missed dose and continue the pack as normal.

Do not take more medicine to make up for the missed dose. If you take more than the prescribed dosage of Kliovance, contact your doctor as soon as possible.

Kliovance side effects and cautions

All medications carry the risk of side effects, though not everyone will experience them. It is important to familiarise yourself with the risks associated with the medication you are taking by reading the patient information leaflet which comes with your medication.

Possible side effects of Kliovance may include:

  • Changes in sex drive (libido)
  • Fluid retention
  • Headaches or migraines
  • Indigestion
  • Menstrual bleeding or spotting
  • Mood swings
  • Nausea
  • Pain or tenderness in the breasts
  • Premenstrual-like symptoms
  • Tiredness
  • Vaginal thrush
  • Weight changes

This is not an exhaustive list of side effects. For a more detailed list of side effects, consult the patient information leaflet.

Who can I speak to about side effects?

If you are concerned about any of the possible side effects associated with your medication, speak to one of our doctors who will be happy to answer any query you may have.

Who should not take Kliovance?

Kliovance may not be suitable for women with certain medical conditions. In particular, Kliovance should not be used by women who:

  • Have an inherited blood condition called porphyria
  • Have blood disorders which increase the risk of blood clots such as deep vein thrombosis or pulmonary embolism.
  • Have live disease
  • Have recently had a heart attack, stroke or angina
  • Have unexplained vaginal bleeding
  • Have untreated endometrial hyperplasia (overgrowth of the lining of the womb)
  • Have, had or suspect they have breast cancer
  • Have, had or suspect they have cancer caused by oestrogen, such as endometrial cancer (cancer of the womb)

Kliovance is not a form of contraception. If it has been less than 12 months since you experienced your last period, or if you are under the age of 50, you may be required to use additional forms of contraception to prevent pregnancy.

Kliovance should not be used by women who are pregnant or breastfeeding.

What should I do if I become pregnant while taking Kliovance?

If you become pregnant while taking Kliovance, stop your treatment and consult your doctor as soon as you can.

Staying safe with Prescription Doctor

Before our doctors can issue a prescription, you will be required to fill out a short medical form. Our doctors will review your order to ensure that the treatment is safe for you.

If the doctor approves your order, they will issue a prescription which will be passed on to our pharmacy. Our UK registered dispensing pharmacy will process the order and dispense your medication.

If your order is processed before 3pm, your medicine will be dispatched via a next-day courier in discreet packaging which gives no indication of its contents.

Table of contents

What is Kliovance?

How to take Kliovance?

Side effects and cautions

Staying safe with Prescription Doctor

Additional resources

10 questions about the menopause answered

Treatment information

  • Product Name: Kliovance
  • Manufacturer: Novo Nordisk
  • Active Ingredient(s): Estradiol and Norethisterone
  • Administration: Oral
  • Presentation: Tablets
  • Available strength: 1 mg Estradiol/0.5 mg Norethisterone
  • Exemption: Prescription Only
  • Application: Postmenopausal women
  • Dosage: 1 tablet daily
  • Description: A hormonal treatment for postmenopausal women
  • Drug Class: Hormone replacement therapy (HRT)
  • Alcohol Consumption: No influence
  • When Pregnant: Do not take Kliovance
  • When Breastfeeding: Do not take Kliovance
Click here to view the Kliovance - Patient Information Leaflet

Menopause Alternatives


  • Treats symptoms of the menopause
  • Available to re-order
  • Prescribed by a registered doctor
View Treatment


  • Treats symptoms of the menopause
  • Repeat prescription available
  • Prescribed by a registered doctor
View Treatment


  • Relieves symptoms of the menopause
  • Available for reorder
  • Prescribed by a registered doctor
View Treatment


  • Easy to apply transdermal patch
  • Available to reorder
  • Prescribed by a registered doctor
View Treatment


  • Increases progesterone levels
  • Reduces postmenopausal symptoms
  • Available from UK registered pharmacy
View Treatment


  • Relieves postmenopausal symptoms
  • Available to reorder
  • Prescribed by a registered doctor
View Treatment


  • Easy to use pump
  • Prevents osteoporosis
  • Dispatched via a next-day delivery
View Treatment


  • Easy to apply patch
  • Reduces menopause symptoms
  • Available from a UK registered pharmacy
View Treatment
Customer Service