Utrogestan

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Patient Reviews: How Utrogestan Has Made a Difference

Treatment Information

Table of contents:

What Is Utrogestan?

Utrogestan is a brand of hormone replacement therapy (HRT) for menopause. It contains a body-identical progesterone, which should be used alongside an oestrogen-based HRT to protect the womb lining from thickening and reduce the risk of womb (uterine) cancer. Together, oestrogen and progesterone HRT are used to relieve symptoms of the menopause in women who have not undergone a hysterectomy, so still have a womb.

Utrogestan is available as a soft capsule, and each one contains 100 mg of micronised progesterone. It can help to manage hot flushes, night sweats, and anxiety in combination with oestrogen HRT, such as patches.
 

How Does Utrogestan Work for Menopause?

Menopause involves hormonal changes that lead to the reduction of natural sex hormones, affecting ovulation and the shedding of the endometrium. Common symptoms include:

  • Difficulty concentrating
  • Difficulty sleeping
  • Headaches
  • Hot flushes
  • Joint pain
  • Recurrent UTIs
  • Reduced muscle mass
  • Reduced sex drive
  • Vaginal dryness

During menopause, the natural levels of oestrogen and progesterone decline, resulting in many of the classic signs and symptoms mentioned above. Research shows that by replacing declining progesterone levels, micronised progesterone (Utrogestan) helps prevent the womb lining from becoming too thick and may alleviate some menopause symptoms, such as sleep disturbances.

When taken alongside oestrogen, Utrogestan 100 mg capsules can also help reduce the extra risk of endometrial (womb) cancer that can occur with oestrogen-only HRT.

Utrogestan is not a type of contraceptive, so if it is less than 12 months since your last period or you are under 50 years old, you may still need additional contraception to stop you getting pregnant. At Prescription Doctor, we can help find the right contraception method for you and can provide:

If you think you may need emergency contraception, our clinician can also prescribe the morning-after pill. 

Why Are Oestrogen and Utrogestan Used Together?

Oestrogen and Utrogestan are used together as a form of combined hormone replacement therapy to treat menopause symptoms in people who still have a womb, i.e., have not had an operation to remove their womb (hysterectomy). The main reason for this combined method is to protect the lining of the womb.

Oestrogen is the main hormone used to prevent symptoms such as hot flushes, night sweats, and vaginal dryness, but it causes the womb lining to thicken. If the womb lining becomes too thick and is not shed, it increases the risk of developing womb or endometrial cancer. One study found that the risk of womb cancer in postmenopausal individuals with a thickened endometrium is 1.178 times higher compared to a control group.

 

How Effective Are Utrogestan Capsules?

Adding Utrogestan to an oestrogen HRT effectively lowers the risk of endometrial cancer in people who still have a womb during menopause. One study found that adding progesterone HRT for more than 25 days per month reduces the risk to levels lower than those seen in non-hormone users.

Another study found that 300 mg of progesterone, a dose far higher than the prescribed 100 to 200 mg of Utrogestan, can effectively reduce menopausal hot flushes and night sweats by 55% and improve sleep. 

 

Utrogestan 100mg: How to Use

Utrogestan is available as 100 mg soft capsules that you swallow whole with a glass of water. You should take Utrogestan at bedtime and without food, and at the same time as your oestrogen HRT.

The usual dose of Utrogestan is 200 mg per day at bedtime. This means you will usually need to take 2 capsules together. Utrogestan is only taken for 12 days during the last half of each menstrual cycle. Sometimes a doctor may prescribe 100 mg of Utrogestan at bedtime every day from days 1 to 25 of each cycle.

To take Utrogestan, you need to:

  • Take two capsules at bedtime on days 15 to 26 of your 28-day cycle.
  • After this, you will usually have a few days of withdrawal bleeding, similar to a period, but you should continue to take your oestrogen HRT every day.
  • If you have any issues with the withdrawal bleed, your doctor may change the way you take Utrogestan to reduce the amount of withdrawal bleeding you have.

What to Do if You Forget to Take Utrogestan

If you forget to take a dose of Utrogestan, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the next one at the usual time. Do not take a double dose to make up for a missed dose. 

What If I Take More Utrogestan Capsules Than Necessary?

If you take too much Utrogestan, you may feel drowsy, dizzy, sleepy, or tired. Contact your doctor if you have taken more Utrogestan than you have been prescribed or if you get any of these symptoms. In an emergency, go to your nearest hospital for medical help, and make sure you take the medicine pack with you so a doctor can see what you have taken. 

 

Utrogestan Side Effects and Cautions 

Understanding the risks associated with taking this medication is important before taking it. If you have any concerns about Utrogestan side effects, speak to a doctor or pharmacist.

Utrogestan 100mg Side Effects

Like all medications, Utrogestan can cause side effects in some people, but not everyone will get them. Because Utrogestan contains a body-identical form of progesterone, meaning it is chemically identical to the natural hormone produced by the body, it often leads to fewer side effects compared to older synthetic types.

Possible Utrogestan side effects include:
 

Common Side Effects
(may affect up to 1 in 10 users)

Uncommon Side Effects
(may affect up to 1 in 100 users)

Rare Side Effects
(may affect up to 1 in 1,000 users

Very Rare Side Effects
(may affect up to 1 in 10,000 users)

Weight changes
Insomnia
Feeling tired or dizzy
Headaches
Stomach swelling or pain
Nausea
Itching
Irregular periods of bleeding between periods
Vaginal bleeding
Breast pain
Missing or absent periods
Feeling generally unwell

 
Problems due to the formation of blood clots in blood vessels
Fluid retention
Anxiety or agitation
Lack of interest or energy
Depression
Disorientation
Mood swings
Nervousness
Memory loss
Migraine
Numbness, tingling, pins and needles
Speech disorder
Fainting
Vision changes
Abnormal menstrual cycle
Breast discomfort or tenderness
Excessive hair
Changes in glucose tolerance
Changes in libido (sex drive)
Eye irritation
Loss of appetite
Painful urination

 
Tan or dark skin discolouration
Allergic reactions
 

 

It’s important to note that the above is not an exhaustive list of Utrogestan 100mg side effects. More detailed information can be found within the Patient Information Leaflet that comes with the medication.

If you get any Utrogestan side effects, you should report them to your doctor or the Medicines and Healthcare products Regulatory Agency Yellow Card Scheme

Utrogestan Cancer Risk

Taking oestrogen-only HRT can increase the risk of excessive thickening of the womb lining and endometrial cancer in women who still have a womb. Utrogestan is taken with oestrogen HRT to help protect against this extra risk by making you shed the womb lining. Combined HRT may still carry other risks, so discuss your individual benefits and risks with a clinician.

Breast Cancer

Utrogestan is used alongside oestrogen in menopausal women, and this type of HRT may slightly increase the risk of breast cancer. For example, in women aged 50 to 79 who:

  • Are not taking HRT: On average, 9 to 17 in 1000 will be diagnosed with breast cancer over a 5-year period
  • Are taking an oestrogen-progesterone HRT: Over 5 years, there will be 13 to 23 cases in 1000 users or an extra 4 to 6 cases

However, the evidence can be mixed. Some research shows that taking oestrogen with micronised progesterone does not increase breast cancer risk for up to 5 years of treatment.  

Ovarian Cancer

Although ovarian cancer is rare, there is a slightly increased chance of getting it in people who take oestrogen-only or combined oestrogen-progesterone HRT. For example, in women aged 50 to 54 who:

  • Are not taking HRT: About 2 in 2000 will be diagnosed with ovarian cancer over a 5-year period
  • Have been taking HRT for 5 years: Around 3 in 2000 users will be diagnosed with ovarian cancer

That means that there will be approximately 1 extra case of ovarian cancer in the HRT group compared to those not taking HRT.

Utrogestan Blood Clot Risk

HRT users are at a 1.3 to 3 times higher risk of blood clots in a vein, especially in the first year, compared to non-HRT users. For example, in women in their 50s who are not taking HRT, over a 5-year period, 4 to 7 out of 1000, on average, will get a blood clot in a vein. In comparison, for the same age group who have taken combined HRT for 5 years, 9 to 12 out of 1000 users will get a blood clot.

There are some factors that can increase the chance of a blood clot in a vein, including:

  • Being unable to walk for a long time because of surgery, illness, or injury
  • Being seriously overweight (a body mass index above 30)
  • Having a blood-clotting issue that requires medication
  • Having a close relative who has had a blood clot in the leg, lung, or any other organ
  • Having systemic lupus erythematosus (SLE)
  • Having cancer

If any of these apply to you, you must speak to your clinician before starting Utrogestan, as it may not be suitable for you.  

 

Utrogestan Interactions and Warnings

Utrogestan is not suitable for everyone. Some medical conditions and medications may make it unsuitable for you. It is important to check the patient information leaflet before taking Utrogestan to ensure you do not have a medical condition or are taking a medicine that may interact with Utrogestan.

Do not take Utrogestan if you:

  • Are allergic to progesterone, soya, peanuts, or any other ingredients listed in the medication
  • Have ever had breast cancer
  • Have oestrogen-sensitive cancer, such as endometrial cancer
  • Have unexplained vaginal bleeding
  • Have excessive thickening of the womb lining (endometrial hyperplasia)
  • Have or have ever had a blood clot in a vein, such as in the legs or lungs
  • Have a blood-clotting disorder
  • Have recently had a disease caused by blood clots in the arteries, such as a heart attack, stroke, or angina
  • Have or have ever had liver disease, and your liver function tests have not yet returned to normal
  • Have a rare blood problem called porphyria
  • Have bleeding on the brain (cerebral haemorrhage)
  • Are breastfeeding

Tell the clinician during your consultation about any medical conditions you have, including any that aren’t listed here, so they can check if Utrogestan is right for you.

Utrogestan Interactions

Before taking Utrogestan, tell the clinician about any prescribed, over-the-counter, or herbal medications you are taking. This will help them ensure that Utrogestan is safe for you to take, as some medications can interact with Utrogestan and make it less effective or potentially unsafe.

Tell the clinician if you are taking any of the following medicines:

  • Blood thinners, such as coumarins or phenindione
  • Ciclosporin or tacrolimus 
  • Tizanidine
  • Bromocriptine
  • Selegiline
  • Diazepam, chlordiazepoxide, alprazolam, oxazepam, or lorazepam
  • Tuberculosis medications, such as rifampicin and rifabutin
  • Antibiotics
  • Phenytoin, phenobarbital, carbamazepine, eslicarbazepine, oxcarbazepine, primidone/rufinamide, perampanel, or topiramate
  • St John’s Wort
  • Darunavir, nelfinavir, fosamprenavir, or lopinavir
  • Bosentan
  • Fluconazole, itraconazole, voriconazole, or ketoconazole
  • Atorvastatin or rosuvastatin
  • Aprepitant

You should also let the clinician know if you have recently been given an anaesthetic or if you have recently been tested for liver or hormone problems.

When to Take Care with Utrogestan and HRT

Before starting Utrogestan, inform your clinician about any medical conditions or risks you have, as they may worsen while taking HRT. You may also need more frequent check-ups.

Tell the clinician if any of the following apply to you:

  • Abnormal tumours/growths (fibroids inside your womb)
  • Growth of the womb lining outside your womb (endometriosis) or a history of excessive growth of the womb lining (endometrial hyperplasia)
  • Increased risk of developing blood clots
  • Increased risk of getting an estrogen-sensitive cancer (such as having a mother, sister or grandmother who has had breast cancer)
  • High blood pressure
  • Liver problems, such as a benign liver tumour
  • Diabetes
  • Gallstones
  • Migraine or severe headaches
  • A disease of the immune system that affects many organs of the body (systemic lupus erythematosus, SLE)
  • Epilepsy
  • Asthma
  • A disease affecting the eardrum and hearing (otosclerosis)
  • A very high level of fat in your blood (triglycerides)
  • Fluid retention due to cardiac or kidney problems
  • Hereditary and acquired angioedema
  • You have ever had depression
  • Your skin is sensitive to light (photo-sensitivity)

You can find more information in the Patient Information Leaflet that is provided with your medication.

Utrogestan During Pregnancy and Breastfeeding

Do not take Utrogestan if you are pregnant, think you might be pregnant, plan on becoming pregnant, or are breastfeeding.

Utrogestan is not a contraceptive. If you become pregnant while taking Utrogestan, stop taking the medicine and consult your doctor immediately.

If you are under 50, or if it has been less than 12 months since your last period, you should use additional forms of contraception, such as condoms, to prevent pregnancy while taking Utrogestan.

 

Where Can I Buy Utrogestan in the UK?

Utrogestan is a prescription-only medication, which means a clinician must approve it for you before you can take it. You will need a short consultation to ensure it is safe for you to take, based on your medical history, whether you get it on the NHS or via a private prescription.

Can I Buy Utrogestan Over the Counter?

No, Utrogestan is not available over the counter; you need a prescription from a qualified clinician.

Is Utrogestan on the NHS?

Yes, Utrogestan is available on the NHS, and is usually prescribed alongside oestrogen for menopausal women who still have their womb intact. You will need to make an appointment with your GP to find out if Utrogestan is available in your area and if it is suitable for you.

Can I Buy Utrogestan Online?

Yes, you can get Utrogestan online from Prescription Doctor after completing a short online health questionnaire for our clinician to assess. It cannot be bought without a consultation or a valid prescription. At Prescription Doctor, we can provide a prescription and dispatch your medication to your home address as part of our regulated service.

Frequently Asked Questions About Utrogestan 100mg Capsules

Can You Take Utrogestan Without Oestrogen?

Although it is possible to take Utrogestan without oestrogen, it is not the standard recommendation for HRT if you still have a womb. It is typically prescribed alongside oestrogen, but in some cases it may be prescribed alone for relief of insomnia or anxiety.

Can You Take Utrogestan Vaginally?

If you are interested in taking Utrogestan vaginally, you will need Utrogestan vaginal capsules, which are specifically designed to be inserted inside the vagina. Vaginal capsules are usually used for IVF, but some clinicians may prescribe Utrogestan vaginal capsules if there is a shortage of the oral capsules, or a 200 mg strength may be a suitable alternative.

At Prescription Doctor, we cannot provide vaginal capsules for taking Utrogestan vaginally. Instead, the capsules we provide are for oral use only.

When Do You Bleed on Utrogestan?

You will usually get a withdrawal bleed a few days after you finish taking the capsules, often around day 27 or 28 of a 28-day cycle. It will usually appear as a light period or spotting. However, it is common to experience irregular bleeding or spotting in the first 3 to 6 months of starting HRT.

If you are concerned about bleeding while taking Utrogestan, speak to your clinician for more advice. 

Is Utrogestan a Progesterone?

Yes, Utrogestan is micronised progesterone. Unlike synthetic progestogens, Utrogestan is chemically identical to the progesterone made by the ovaries and is associated with a lower risk of side effects, such as blood clots and breast cancer.

Is Utrogestan Body Identical?

Yes, Utrogestan is a body-identical progesterone, meaning it is chemically identical to the progesterone produced by the ovaries. It is derived from plants and is often better tolerated, with fewer side effects, than synthetic progestogens. Utrogestan is a micronised progesterone, which means it is broken down into tiny particles for absorption. 

Is Gepretix the Same as Utrogestan?

Yes, Gepretix and Utrogestan are essentially the same medication because they contain the same active ingredient in the same dosages, and are both approved forms of HRT. The main difference is that Gepretix is a branded generic version of Utrogestan, which often makes it more cost-effective.

Does Utrogestan Cause Weight Gain?

Weight changes are listed as a common Utrogestan side effect, affecting up to 1 in 10 people who take it. However, there is no conclusive evidence that Utrogestan causes weight gain. Many people gain weight around the time of the menopause, but this may be caused by hormone changes, age-related metabolism shifts, or temporary fluid retention rather than the medication.

Adopting a healthy lifestyle, such as eating a calorie-controlled, balanced diet, getting regular exercise, and prioritising sleep, can help you maintain a healthy weight. 

How Long Should I Take Utrogestan For?

It's common to take HRT for 2 to 5 years to treat menopause symptoms, but sometimes you may need to take it for longer. The duration depends on individual circumstances and medical advice, including the age at which you started menopause.

For example, if you enter the menopause before the age of 40, known as premature menopause, or before the age of 45 (early menopause), you’ll usually be advised to take HRT until you are at least 51, which is the average age of menopause in the UK. 

How Do I Stop Taking Utrogestan?

Talk to your doctor if you're thinking of stopping taking HRT. They may suggest that you reduce your dose gradually to help prevent your menopause symptoms from coming back. If you're having problems with side effects, your doctor might suggest changing your dose or switching to another type of HRT.

What Should I Do if I Experience Utrogestan Side Effects?

Most Utrogestan side effects are mild and temporary and will usually improve within 3 to 6 months as your body gets used to the medication. It is advisable to take Utrogestan on an empty stomach before bed to reduce the risk of side effects.

If you experience any side effects that are severe or difficult to manage, consult your doctor immediately. Side effects can include dizziness, headaches, and yellowing of the skin and eyes (jaundice).

What Precautions Should I Take While Using Utrogestan?

If you have a history of blood clots, high blood pressure, or liver problems, consult your doctor before starting Utrogestan, as it may not be suitable for you, and you may need regular check-ups.

If you have any concerns about taking Utrogestan, speak to a clinician before taking it.

Additional Resources

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How Quickly Does Utrogestan Work?

This article will give you a better understanding of Utrogestan timing, duration, efficacy, long-term use, and factors that could influence Utrogestan's effectiveness. So, keep reading to find out the answer to ‘How quickly can Utrogestan help treat Menopause?’Speed of ActionUtrogestan is a form of hormone replacement therapy (HRT) that contains the active ingredient progesterone.Utrogesan, like other HRTs, can take up to 3 months to fully improve symptoms, although you may start noticing a difference within a few days to a few weeks.Utrogestan absorption time is approximately one hour, but this may be affected by the amount of food you’ve eaten. As it’s taken at bedtime, it’ll absorb while you sleep.Utrogestan will start to work straight away, but it can take several weeks to build up in your system.Treatment DurationUtrogestan can be taken for as long as needed if you’re still getting menopause symptoms.Utrogestan has a half-life of around 14 to 16 hours. This is how long it takes for half of the active ingredient to be eliminated from your body.Treatment Duration for Different GroupsUtrogestan:Will always be prescribed at the lowest dose possible to alleviate your symptoms.Can only be taken if you’ve been through menopause.Shouldn’t be taken if you are or might become pregnant.Your Utrogestan dose may be adjusted if you have problems with your withdrawal bleed.Long-term UseUtrogestan is a long-term HRT.You can take Utrogestan for as long as needed, which is typically around 2 to 5 years, but in some cases, it may be longer.Risks and Benefits of Long-term UseThe risks of using Utrogestan long-term include:A slightly increased risk of breast cancer and blood clots (which reduces after you stop taking it)The benefits of using Utrogestan long-term include:improved menopause symptomsbetter quality of lifehelps to prevent osteoporosis (weakened bones)Dosage and Factors Affecting EfficacyThe recommended daily dose of Utrogestan is 200mg at bedtime for 12 days in the last half of your HRT cycle. Alternatively, you can take 100mg from day 1 to 25 of your HRT cycle. You and your doctor will determine which treatment regime is best.Utrogestan may be less effective if you:miss a dosetake it with food.You should also take your oestrogen HRT at the same time.What to Do If You Find the Dose IneffectiveIf you don’t think your current dose of Utrogestan is working, wait until you’ve been taking it for around 3 months. If your symptoms haven’t improved, speak to your doctor.ConclusionUtrogestan's efficacy is high, making it a well-tolerated form of HRT. It will either be taken daily or for the first 12 days of your HRT cycle. It can take around 3 months to get the best effect from your treatment. Utrogestan can be taken long-term; however, if you have further questions, consult a healthcare provider.You can also speak with one of our prescribers about a tailored HRT treatment plan, or find more help and support on HRT on our website.Additional ResourcesUtrogestan's Role in Treating Menopause SymptomsExploring the Uses of Utrogestan in Medical TreatmentYour Top 10 Menopause Questions Answered ThoroughlyIdentifying and Managing the 34 Symptoms of MenopauseEffective Strategies for Weight Loss During MenopauseDuration of Menopause: What to Expect and How to CopeCan You Get Your Period While On Utrogestan?SourcesEMC, 2022. Utrogestan 100mg Capsules: EMC Product Information.NHS, 2023. How and When to Take Utrogestan: NHS Medicine Guide.NHS, 2023. About Utrogestan: NHS Medicine Guide.
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How Quickly Does Utrogestan Work?
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What is Utrogestan Used For?

Utrogestan 100mg is a type of Hormone Replacement Therapy (HRT) used to treat symptoms of menopause. It contains the active ingredient progesterone, which helps replace your naturally declining progesterone levels, thereby reducing symptoms such as hot flashes, mood changes, and night sweats.Utrogestan contains the active ingredient progesterone, which is made from plants. The medication has become popular over recent years as it’s identical to the human body’s progesterone. Because of this, Utrogestan is often well-tolerated.Utrogestan is usually prescribed alongside another HRT containing oestrogen. Below, we examine the uses of Utrogestan 100mg.What is Utrogestan used for?Utrogestan is a form of HRT that can reduce postmenopausal symptoms. It is prescription only and needs to be taken alongside oestrogen. This is because:Taking oestrogen on its own can cause the lining of your womb to build up, which may increase the risk of womb cancer.Using Utrogestan alongside an oestrogen will make you shed the lining of your womb to protect against womb cancer.Utrogestan should only be used if you still have a womb. It is not a contraceptive, so you should still use another form of contraception if you want to protect against pregnancy.Mechanism of Action - How Utrogestan is Used in HRT?As you go through menopause, your levels of oestrogen and progesterone decrease naturally. This slows down your period and eventually stops it altogether. With a change in hormone levels comes symptoms, such as anxiety, low mood, changes in skin, and difficulty sleeping.To counteract this, HRT like Utrogestan is used to replace declining hormones and reduce symptoms so you can live your life again.Taking Utrogestan is beneficial because it:can reduce the risks associated with taking oestrogen on its own, such as a build-up in the lining of your wombreplaces progesterone levels, which can make you feel bettercontains progesterone, which is identical to the body’s hormone, unlike some HRTs that use man-made hormones - this means you may be less likely to get side effectsHow is Utrogestan administered?Always take Utrogestan as prescribed. You will usually start on the lowest dose, but please let your doctor know if your dose feels too strong or if it is not managing your symptoms.The recommended dose of Utrogestan 100mg capsules is:2 capsules (200mg) once daily before bed, taken from day 15 to day 26 of your HRT cycle1 capsule (100mg) once daily before bed, taken from day 1 to day 25 of your HRT cycleEach HRT cycle will mimic a 28-day menstrual cycle. When you stop taking Utrogestan, you will usually have a withdrawal bleed, which is like a period.Take Utrogestan together with your oestrogen HRT by swallowing it whole, with a glass of water. It should only be taken at bedtime. Do not take Utrogestan with food.Other Utrogestan UsesUtrogestan uses are mainly for HRT, but it can also be used to:Improve the chances of pregnancy for women using IVFPrevent a preterm birthConclusionUtrogestan 100mg is used for treating menopausal symptoms that impact your daily life. It’s prescribed alongside oestrogen to alleviate symptoms and prevent the risk of womb cancer. If you are going through menopause, speak to your doctor or one of our prescribers to get a tailored HRT treatment plan, which may include Utrogestan.Additional ResourcesHow Utrogestan Relieves Menopause Symptoms?When Does Utrogestan Start Working?How to Take Utrogestan for Menopause?What Are the Top Menopause Questions?What Are Menopause Symptoms?How to Lose Weight During Menopause?How Long Does Menopause Last?Can You Get Your Period While On Utrogestan?SourcesNHS, 2023, About Utrogestan.EMC, 2023, Product Information.NHS, 2023, How and When to Take Utrogestan.
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What is Utrogestan Used For?
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How To Take Utrogestan?

If you’re considering using medication to either treat a health condition or manage something significant like menopause, there are several important elements to understand before you get started. One of the main points is exactly how to administer the treatment, as using the medication as prescribed is crucial to ensuring it works as intended.  With this in mind, this article explores how to take Utrogestan for menopause, the best time to administer it, and optimal treatment regimens. We also explore common dosage issues and answer frequently asked questions. Let’s get started.    [medical_form product_id="131" text="START YOUR CONSULTATION TODAY" type="button"] What Are Utrogestan Tablets?Utrogestan is a form of progesterone – a hormone that plays a key role in the female reproductive system. Progesterone helps regulate the menstrual cycle and prepares the lining of the womb (endometrium) for pregnancy. During menopause, progesterone levels drop significantly, which is why it's often prescribed as part of hormone replacement therapy (HRT).If you still have your womb and are taking oestrogen as part of HRT, you'll need to take a progesterone like Utrogestan alongside it. Without progesterone, oestrogen can cause the womb lining to thicken abnormally, which increases the risk of endometrial hyperplasia and potentially endometrial cancer. Utrogestan prevents this by prompting the womb lining to shed regularly.That's why Utrogestan is always prescribed alongside oestrogen – the two work together as part of your HRT. Utrogestan 100mg: How to UseUtrogestan 100mg capsules should be taken once daily at bedtime, without food. Your prescribed dose will be either 1 or 2 capsules, taken for 12 or 25 days. You'll always have a short break, which may cause breakthrough bleeding. Utrogestan is to be taken alongside an oestrogen.The typical dosage is 2 capsules (200 mg) at bedtime for 12 days, on days 15 to 26 of your monthly HRT cycle. You may also be prescribed a lower dose of 1 capsule (100 mg) at bedtime, from day 1 to 25 of each monthly HRT cycle. Your doctor will start with the lowest dose to manage your symptoms, but please let them know if you think your dose is too high or too low.Regardless of the prescribed dose, you will have a brief break between packs. This usually causes a breakthrough bleed, where the lining of your womb sheds, much like a period. When to Take Utrogestan  The timing of your Utrogestan dose depends on which HRT regimen your doctor has prescribed. There are two main strategies, and understanding the difference will help you take your medication correctly.  If You’re Still Having PeriodsIf you're still having periods (perimenopausal), you'll typically follow a sequential regimen – taking 2 capsules (200mg) at bedtime for 12 days of each 28-day cycle, usually on days 15 to 26. You'll then have a short break before starting the next cycle, during which you may experience a withdrawal bleed.If Your Periods Have StoppedIf your periods have stopped for 12 consecutive months or more (postmenopausal), your doctor may recommend a continuous regimen: taking 1 capsule (100mg) at bedtime on days 1 to 25 of each 28-day cycle. Some doctors may advise taking it daily without a break; in that case, you will usually not experience bleeding once your body adjusts.Regardless of the regimen you follow, always take Utrogestan at bedtime, at least 2 hours after eating, and swallow the capsules whole with water.Can You Take Utrogestan Every Day?In most cases, Utrogestan is not taken every single day. The standard prescribing approach includes a short break – either a few days off at the end of each cycle (sequential regimen) or a 3-day gap between day 25 and the start of the next cycle (continuous regimen).However, there are exceptions. According to the NHS, your doctor may sometimes advise taking Utrogestan every day if they feel it's appropriate for you – particularly if you're postmenopausal and they want you to avoid monthly bleeding altogether. In this case, you'd take 100mg at bedtime continuously.The reason most regimens include a break is to allow the womb lining to shed, which helps prevent endometrial hyperplasia – a thickening of the lining that can increase the risk of womb cancer over time. {add_product_block(131)} Why Do Most Utrogestan Treatment Regimens Include a Break?When you take oestrogen as part of HRT, it encourages the lining of your womb to grow. That's completely normal – it's what oestrogen naturally does. Progesterone's job is to keep that growth in check by prompting the lining to shed, much like it does during a natural menstrual cycle.The scheduled breaks in your Utrogestan regimen are intended to allow shedding to occur. Without those breaks, the womb lining could build up over time, which increases the risk of a condition called endometrial hyperplasia – and in some cases, womb cancer.This is also why your doctor will usually prescribe Utrogestan for at least 12 days each month – that's enough time to properly protect your womb lining. Taken this way, it has been shown to be safe for up to five years.That said, some postmenopausal women are prescribed Utrogestan continuously under their doctor's guidance – particularly if they've been period-free for over a year and want to avoid monthly bleeding. When is the Best Time to Take Utrogestan?The best time to take Utrogestan is at bedtime, as it can cause mild drowsiness. Utrogestan should always be taken with your oestrogen.Can I Take Utrogestan in the Morning?You may be able to take Utrogestan in the morning, but consult your doctor first to determine if you can tolerate it. Because it can cause mild drowsiness, most are better off taking it at night. What Happens if I Take Utrogestan with Food?Utrogestan should be taken without food, approximately 2 hours after eating. Taking progesterone with food can increase its bioavailability (how much of the medication is absorbed), which may intensify side effects. This may lead to higher blood levels or increased drowsiness.Can I Eat After Taking Progesterone?It's best to avoid eating for at least an hour or so after taking Utrogestan. Since the medication should be taken at bedtime, this is usually straightforward – most people take their capsule as the last thing they do before going to sleep.If you feel hungry after taking your dose, a very light snack is unlikely to cause problems, but a full meal could increase absorption and potentially intensify side effects such as drowsiness. As a general rule, wait 2 hours after eating before taking Utrogestan, and avoid eating again until the morning.   Utrogestan Dosage Issues ResolvedDetermining the appropriate Utrogestan dosage may require adjustments. Your doctor will aim to prescribe the lowest effective dose to manage your symptoms while providing adequate protection for your womb lining. Here's how common dosage issues are typically handled. Side EffectsIf you're experiencing bothersome side effects such as bloating, mood changes, or excessive drowsiness, your doctor may consider lowering your dose or adjusting your regimen. For instance, switching from a 200mg sequential dose to 100mg taken on more days of the cycle can sometimes reduce side effects while maintaining endometrial protection.Unscheduled BleedingIf you're experiencing unscheduled bleeding beyond the first 3 to 6 months, your doctor may need to increase your progesterone dose or extend the number of days you take it each cycle. The British Menopause Society advises that the dose of progesterone should be proportionate to the dose of oestrogen you're taking.Always discuss any concerns with your prescriber. You should never adjust your dose independently. Utrogestan Missed Dose: What Do I Do?If you forget to take Utrogestan, take your dose as soon as you can. If your next dose is due, skip the missed dose and continue with your regular schedule. Don’t take a double dose to make up for a missed dose, as this will only increase the risk of side effects.I Forgot to Take Utrogestan for a Week. What Happens Now?Resume taking your Utrogestan as soon as you remember, following your usual dose and schedule. Don't try to "catch up" by taking extra capsules. You may experience some irregular bleeding or spotting as your body adjusts, which is normal.Missing several days of progesterone means your womb lining hasn't had its usual opposition to oestrogen during that time. This isn't dangerous in the short term, but it's important to get back on track.Contact your doctor or pharmacist for advice, especially if you've been missing doses regularly. They may suggest setting an alarm or using a calendar to help you remember. If you find it difficult to stick to the routine, your doctor might discuss alternative methods of progesterone delivery, such as the Mirena coil.  What if I Take More Utrogestan Than Prescribed?If you take more Utrogestan than prescribed, speak to your doctor or go to the hospital. Take your medication packet with you, so they have a clear indication of what you have taken. You may feel drowsy, sleepy, or dizzy; therefore, do not drive yourself to the hospital. How to Take Utrogestan: Frequently Asked QuestionsHave questions about how to take Utrogestan or what to do in specific situations? Here are answers to the most common questions about this progesterone medication. Is Taking Utrogestan Vaginally Recommended?Using Utrogestan capsules vaginally is not part of its standard licence for HRT. It's considered off-label use, and there is limited clinical data on optimal administration. However, it’s a well-established practice among menopause specialists for women who experience side effects (such as drowsiness or bloating) when taking it orally.According to the British Menopause Society, if vaginal administration is deemed appropriate, progesterone should be given in similar doses and durations as oral intake. This is supported by a clinical study that found lower doses of micronised progesterone resulted in a higher rate of endometrial hyperplasia compared to placebo when administered vaginally.  If you're struggling with oral Utrogestan, speak to a menopause specialist about whether vaginal use might be appropriate for you.Can You Take Utrogestan with Mirena Coils?If you have a Mirena coil, you usually won't need to take Utrogestan as well. The Mirena releases a form of progestogen directly into your womb, which protects the lining in the same way that Utrogestan does – just delivered differently. With a Mirena in place, you'd typically just take oestrogen alongside it.Can You Take Utrogestan On Its Own?Utrogestan is not typically used on its own for HRT. It's prescribed alongside oestrogen to protect the womb lining from the effects of oestrogen therapy. Without oestrogen, Utrogestan wouldn't be providing HRT – it would simply be progesterone without the symptom-relieving benefits of oestrogen replacement. {add_product_block(131)} What Happens When You Stop Taking Utrogestan?If you stop taking Utrogestan, the effects will depend on whether you're also stopping oestrogen or continuing it.If you stop taking Utrogestan but continue taking oestrogen, your womb lining will no longer have progesterone to oppose it. Over time, this can cause the lining to thicken abnormally, increasing the risk of endometrial hyperplasia and potentially womb cancer. This is why the NHS advises keeping Utrogestan or another progestogen for as long as you're taking oestrogen.If you're stopping HRT altogether, your doctor may recommend reducing your dose gradually rather than stopping abruptly, to help prevent menopause symptoms from returning suddenly. Don't stop taking Utrogestan without first discussing it with your doctor. Support Throughout the JourneyIf you’re going through menopause, you’ll want to know you have the backing of a specialist team ready to assist whenever needed. It’s also important that you can discuss the matter discreetly and have straightforward access to the medication you need. This is where you can rely on Prescription Doctor.We’ve made it our mission to take the hassle out of healthcare and offer a streamlined service you can rely upon. We begin with a brief questionnaire that outlines your medical history and details any other treatments you may be taking. This can be completed at any time from your home, so there’s no need for potentially lengthy appointment wait times.  From there, our experienced clinicians review your information to determine whether Utrogestan or your chosen treatment is suitable for your circumstances. If approved, the medication is dispatched by our General Pharmaceutical Council-registered pharmacy in plain packaging to ensure complete discretion. Orders approved before 3pm on a weekday are also eligible for next-day delivery.Our service doesn’t stop there: our clinicians will regularly check in with you to monitor progress and ensure your treatment regimen is working as planned. You can also contact our team for advice whenever you have a query about your medication.  The Prescription Doctor website has a library of articles about Utrogestan and menopause in general, so you can have a wealth of information at your fingertips. So, no matter if you’re wondering how to take Utrogestan, how long it takes to work, or whether you can get your period while using it, we have you covered. We also cover the most common signs of menopause so you can clearly understand potential symptoms.  Ready to take the first steps on your journey? Begin a consultation with Prescription Doctor today. SourcesNHS: How and when to take Utrogestan.NHS: Side effects of Utrogestan.EMC (2024): Utrogestan 100mg Capsules – Summary of Product Characteristics.BMS (2026): Progestogens and endometrial protection.ScienceDirect (2024): Progestogens for endometrial protection in combined menopausal hormone therapy: A systematic review.Climacteric (2016): The impact of micronised progesterone on the endometrium: a systematic review.NHS (2024): What is an IUS (intrauterine system) or hormonal coil?NHS (2023): Types of hormone replacement therapy (HRT). 
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How To Take Utrogestan?
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10 Questions About the Menopause Answered

Menopause is a fact of life that many don't think about until they have to. Women in their reproductive years are often more concerned about birth control and STDs.Men don't experience menopause, although they do undergo similar age-related changes.In recent years, more women have started discussing menopause. Although they are more open about it, some are still left with questions.1.) What is the menopause?The menopause occurs in a woman after age-related declines in hormones cause her to stop menstruating. The main hormones that decline during menopause are oestrogen, progesterone and testosterone.A woman is considered to be fully in menopause after 12 months without menstruation. After this time, pregnancy is unlikely.2.) What age does the menopause hit?On average, women experience the menopause between the ages of 45 and 55. A woman may begin to experience fewer periods as she approaches menopause, or she may stop menstruating suddenly.One in 100 women hit menopause before age 40 - this is called premature menopause and is usually caused by ovarian failure, damage to the ovaries or surgical removal of the ovaries.3.) How long does the menopause last?On average, the menopause lasts about four years. The time leading up to menopause is called perimenopause, and the time after menopause is called post-menopause.Symptoms begin to develop during perimenopause and ease off during post-menopause.4.) What are the symptoms of the menopause?Some common symptoms are:changes in moodchillsdry skinhot flashesirregular periodsloss of breast fullnessnight sweatssleep problemsslow metabolism and weight gainthinning hairvaginal dryness5.) How is the menopause diagnosed?Doctors typically diagnose the menopause based on the description of the symptoms, though some women experience few symptoms.There are also home menopause test kits which can tell you if you are menopausal.6.) When is it safe to stop using contraceptive pills?The combined contraceptive pill can mask symptoms of the menopause, making it difficult to diagnose. Thus, it is recommended to stop taking combined contraceptive pills before the age of 50 and switch to another form of contraception, such as the progestogen-only pill, also known as the mini pill.Of course, condoms are the only contraceptive method which can prevent sexually transmitted diseases (STDs). They can be used after the menopause.7.) Can the menopause affect hair and skin?Yes. During the menopause, androgen levels increase. Androgens, such as testosterone, determine male characteristics, including facial and body hair. As a consequence, some women may notice an increase in unwanted facial and body hair.The drop in oestrogen and progesterone slows down hair growth, causing hair on the scalp to appear thin.Since the body stops making as much collagen during menopause, the skin loses elasticity and becomes dry. This can create sagging skin around the cheeks and jawline, as well as increase the appearance of wrinkles around the eyes.8.) Is it possible to delay the menopause?One study published in the Journal of Epidemiology and Community Health found that women who eat a diet rich in fish, legumes, beans, B12, and zinc reach menopause later than women whose diet contains simple carbohydrates, such as refined rice and pasta.Another US study showed that women who ate more low-fat milk products delayed menopause by over three and a half years. It's thought that enzymes in the cow milk could boost oestrogen levels.However, the findings of both studies only demonstrated a possible relationship between the factors, not a probable cause. That is to say that while diet may have an effect on the age at which women experience the menopause, there are several other factors to consider that could influence the cessation of the menstrual cycle, the primary indicator of menopause.9.) How does a partial hysterectomy affect the menopause?A partial hysterectomy removes just the womb, but the cervix and ovaries remain intact.Evidence indicates that women who undergo a partial hysterectomy are at an increased risk of ovarian failure and, hence, early menopause.It is not known if this is caused by the hysterectomy itself or another pre-existing cause.10.) Is there a cure for menopause?While there is no cure for the menopause, there are a variety of treatments to manage the symptoms.If you experience uncomfortable symptoms, there are treatments available to help manage them and bring relief.Hormone replacement therapy (HRT) is a common menopause treatment that's available online.After the menopause transition is complete, most symptoms either disappear or subside to a more manageable level. Women no longer have to worry about birth control or monthly menstrual cycles.They are now free to enjoy life on their own terms.
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10 Questions About the Menopause Answered
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What Are the 34 Symptoms of the Menopause?

Menopause is a pivotal event in women’s lives, due to its wide-reaching impact and the significant changes involved. If you’re approaching menopause or would like to better understand what to expect, researching potential symptoms is crucial. While not everyone might experience the same things, it’s still worth finding out as much information as possible.In this article, we’ll answer important questions such as “Am I going through menopause?” and “What are the 34 symptoms of menopause?”, as well as discuss some early signs to be aware of and explore the different medications you can take. Let’s begin.  [medical_form product_id="471" text="START YOUR MENOPAUSE CONSULTATION TODAY" type="button"] What Does Menopause Mean?Menopause is a natural part of the female ageing process and describes the stage in a woman’s life when her periods stop. This change is permanent, and women can no longer get pregnant after menopause. The time leading up to menopause is called perimenopause, or the menopausal transition.Some women experience a variety of menopausal symptoms, while others have mild symptoms or none at all. Many people consider the perimenopausal stage part of menopause, but true menopause isn’t confirmed until at least one year has passed since a woman’s last period.At What Age Does Menopause Begin?Menopause usually begins between the ages of 45 and 55. However, it can happen earlier than this and may not be age-related. Premature menopause, defined as occurring before the age of 40, and early menopause, which affects women from 40 to 44, have several possible causes.For example, some women experience early menopause because of surgeries that remove the womb (hysterectomy) or ovaries (oophorectomy). Early menopause may also be triggered by chemotherapy or genetic factors. Other potential contributors to premature and early menopause include:SmokingHigh blood pressureThyroid disease  What are the 1st Signs of Menopause?Menopause symptoms can vary significantly between women, making it harder to establish when the menopausal transition has begun. However, the early signs of menopause commonly include:Changes in the regularity of periodsHot flashesNight sweatsBladder incontinenceSleep problemsVaginal drynessMood changesBrain fogNot all women experience menopause symptoms, but around 75% have them to some degree. For some women, these symptoms are mild and can be managed with small lifestyle adjustments, while for others, they are more severe. The symptoms of menopause last an average of 7 years, though they can continue for over 10 years in some women.What are the 34 Symptoms of Menopause?The symptoms of menopause are diverse, and not every woman has the same experience. There are around 34 menopause symptoms, ranging from physical issues (like hot flashes and headaches) to emotional and cognitive problems (such as mood swings and memory loss). {add_product_block(471)} 1. Hot FlashesHot flashes, the most common type of menopause vasomotor symptom, are sudden, short bursts of heat that cause redness and flushing around the face, neck and chest. This can be very uncomfortable, and some women find hot flashes disrupt their daily lives. For some people, small changes in their daily routine can help manage hot flashes. However, others may require hormonal or non-hormonal medications to reduce their symptoms.2. Period ChangesChanges in periods are a common sign of perimenopause and a result of fluctuating hormone levels. As women enter the menopausal transition, their ovaries start producing different amounts of oestrogen and progesterone, which play key roles in regulating menstruation.Your periods may become less regular, with cycles that are heavier, lighter, longer, or shorter than they used to be. Some women have periods that occur very close together, while others may skip a few months. Irregular periods continue for 2-8 years before stopping altogether.  3. Night SweatsHot flashes that happen at night are called night sweats. Some women with night sweats wake frequently, which can significantly disrupt sleep. It may be possible to manage night sweats with small dietary and lifestyle changes, or with prescription hormonal or non-hormonal medication.4. Poor Sleep QualityPoor sleep quality is a common issue for women experiencing menopausal transition. Many symptoms, such as night sweats and mood changes, can interrupt sleep and contribute to chronic sleep problems, like insomnia. Developing healthier sleep habits may help to improve sleep quality, as can medications like melatonin.5. Heart Palpitations Heart palpitations (which are rapid, irregular, or exaggerated heartbeats) affect up to 42% of perimenopausal women and 54% of postmenopausal women. This is another example of a vasomotor symptom, and studies have shown that cognitive behavioural therapy (CBT) can improve palpitations, night sweats, and hot flashes. Maintaining a healthy diet, frequent exercise, managing anxiety, and avoiding alcohol may also help to reduce heart palpitations.6. HeadachesHeadaches and migraines can change in severity and frequency during menopause. For some women, migraine symptoms worsen during the menopausal transition, possibly as a result of fluctuating oestrogen levels. Other types of headaches (like cluster and tension headaches) may also increase during menopause.   7. Mood SwingsMenopause is often associated with sudden mood swings, which can cause intense and unpredictable shifts in emotional state. Other mental health problems that can flare up during menopause include anxiety, depression, and stress. Alterations to mental well-being can happen because of changing hormone levels, but can also be exacerbated by sleep problems.8. Vaginal DrynessHormone fluctuations during the menopausal transition can bring about physical changes in the vagina. The inner lining of the vagina can become thinner, causing symptoms like vaginal dryness, burning, itching, and irritation. Genitourinary symptoms (i.e., symptoms affecting the genitals and urinary tract) affect an estimated 50-75% of women going through menopause.9. Memory LossMany menopausal women experience memory issues and brain fog, possibly because of declining oestrogen levels. This affects several aspects of cognitive function, including working memory, attention, processing speed, and verbal memory. Fortunately, many women find their memory problems improve after menopause, once their hormone levels stop fluctuating.10. TirednessSleep problems and hormonal fluctuations during the menopausal transition leave many women feeling fatigued. One study found that 46.5% of perimenopausal women and 85.3% of post-menopausal women felt physically and mentally exhausted, compared with just 19.7% of pre-menopausal women.  11. Loss of Sex DriveLoss of sex drive is common during menopause, as declining hormone levels can reduce libido. It may take longer to become aroused, and vaginal dryness can make sex uncomfortable or even painful. Other menopause symptoms, like poor sleep quality and mood changes, can also contribute to a lack of interest in sex.12. DepressionMenopause can increase your risk of depression, with one large study reporting rates of 35.6% among menopausal women. Doctors think this is due to changes in hormone levels, which have been associated with depression, irritability, and anxiety. Women who experience vasomotor symptoms (like hot flashes and sleep problems) are more likely to develop depression during menopause.13. AnxietyThe fluctuating hormone levels that characterise menopause may affect serotonin and Gamma-Aminobutyric Acid (GABA) signalling in the brain. This can contribute to mood changes during menopause, including depression and anxiety. Other menopause symptoms, like lack of sleep, can further exacerbate anxiety.14. Weight GainMany women gain weight during the menopausal transition. Weight gain often begins a few years before menopause and continues at about 1.5 pounds per year. However, hormonal changes alone don’t cause weight gain, and it’s usually due to a combination of factors, including ageing, lifestyle, and genetics. If you'd like to know more about losing weight during the menopause, please read our dedicated article.   15. Joint PainsJoint pain affects more than half of women going through menopause, as declining oestrogen levels can increase inflammation in the joints. Low oestrogen levels can also weaken muscle and bone, increasing the risk of osteoarthritis. You may be able to improve joint health and limit pain with low-impact exercise, strength training, and daily stretching.16. Poor ConcentrationPoor concentration, or ‘brain fog,’ affects many women experiencing menopausal transition. Oestrogen has neuroprotective effects, so declining levels may contribute to cognitive issues. Other menopause symptoms, like poor sleep quality and depression, can also impair concentration.17. Hair LossMenopause can cause changes to hair, as low oestrogen levels can impact the health of hair follicles. This may lead to thinning, loss of volume, and changes in hair texture. This phenomenon, called female pattern hair loss, may affect up to 56% of post-menopausal women.18. DizzinessDizziness is one of the most common symptoms of menopause, with 35.7% of women experiencing this symptom weekly. This may be linked to other menopause symptoms, such as anxiety and hot flashes. 19. Urinary Tract InfectionsUrinary tract infections are common among women in all life stages, but their prevalence increases after menopause. This may be because lower oestrogen levels impact the health and function of the vaginal mucosal wall. Thinning of the vaginal wall, impaired immune function and changes in the vaginal microbiota can all increase the risk of UTIs.  20. BloatingMany women experience digestive symptoms during menopause, including acid reflux, abdominal pain, bloating, constipation, and diarrhoea. Bloating is the most common of these symptoms, affecting an estimated 77% of menopausal women. Bloating is caused by a build-up of gas and is often linked to hormonal changes.21. Taste ChangesMenopause can alter taste perception, with some women reporting a reduction in the intensity of sweet and bitter flavours. This effect may have multiple causes, but it is linked to hormonal fluctuations and decreased salivary production during menopause.22. Urinary IncontinenceUrinary incontinence affects over 50% of post-menopausal women and is the most common symptom of Genitourinary Syndrome of Menopause (GSM), a cluster of conditions affecting the genitals and urinary tract. Declining estrogen levels can weaken urogenital tissues, including those supporting the bladder, and lead to urinary urgency and incontinence.23. Digestive IssuesDigestive problems such as diarrhoea, constipation, nausea, vomiting, abdominal pain, bloating, heartburn, and faecal incontinence may be more prevalent among menopausal women than pre-menopausal women. Oestrogen and progesterone play key roles in gastrointestinal health, so declining hormone levels may contribute to digestive issues in menopausal women.24. Muscle StrainMenopause has a profound effect on musculoskeletal health, and more than 70% of menopausal women report musculoskeletal symptoms like muscle strain. Researchers believe that reduced oestrogen levels can lead to a loss of muscle and bone mass, contributing to conditions that affect these tissues. {add_product_block(304)} 25. Dry & Itchy SkinHormonal changes during menopause can make skin thinner and drier.  This is because oestrogen supports skin health, and declining levels can contribute to dryness, which leaves skin feeling tight, flaky, and itchy.26. Change in Body OdourMany women find that their body odour gets stronger during menopause. This may be because a drop in oestrogen levels leaves the body with a relatively higher testosterone level, which can alter the skin's bacterial population. It may attract more bacteria, making sweat smell even stronger. Hot flashes and night sweats can also increase the number of bacteria in the armpits, further contributing to body odour.27. Brittle NailsChanges in oestrogen levels during menopause can affect nail health, making nails more brittle. This is because drops in oestrogen weaken the keratin layers in fingernails, causing them to break more easily. Dehydration can further weaken keratin and contribute to nail breakage, peeling, cracks and splits.28. AllergiesHormonal fluctuations women experience during menopause may contribute to the development of allergies. A reduction in oestrogen levels during menopause can also exacerbate asthma symptoms or lead to the development of asthma in women who didn’t previously have the condition.  29. Electric Shocks Under the SkinDeclining hormone levels during menopause can cause neurological symptoms and odd sensations. These can manifest as electric-shock sensations, which feel like sudden jolts or zaps under the skin. Many women also report experiencing paresthesia, or pins and needles.30. Breast TendernessBreast pain, or mastalgia, affects up to 70% of women and is a common symptom of menopause. Hormonal changes can cause breasts to feel more tender than usual, and they may feel lumpier than they did before. These symptoms often resolve after menopause, when hormone levels drop.31. TinnitusAlmost one-third of women experience new or worsening tinnitus during menopause, and doctors believe declining oestrogen levels are the cause. Oestrogen supports ear health, so having less of it can contribute to tinnitus. Other symptoms like anxiety, lack of sleep, and depression can also make tinnitus worse during menopause.32. Tingling Sensation in ExtremitiesHormonal changes during menopause can manifest as neurological symptoms, including paresthesia - an abnormal tingling or prickling sensation also known as ‘pins and needles.’ Many women experience this sensation in their hands and feet during menopause, though it is usually short-lived.33. OsteoporosisOsteoporosis is a serious medical condition that weakens bones to the point that they become fragile and break easily. The risk of osteoporosis increases with age, but menopausal women are more likely to develop the disease than men. This is because bone mass decreases around menopause, and women may lose up to 10% of their bone density in the 5 years after their periods stop. {add_product_block(453)} 34. Bleeding GumsFluctuating hormone levels can contribute to oral health problems, including dry mouth (xerostomia), gum disease, burning mouth syndrome (BMS), and changes in taste perception. Gum disease can cause gums to bleed, especially when brushing or flossing.How to Manage the Symptoms of MenopauseMost symptoms of menopause are related to natural ageing and the low levels of sex hormones (oestrogen, progesterone and testosterone) a woman produces, as she reaches the menopause period of her life. However, there are several ways you can manage some of these symptoms during menopause, and they include:Hormone replacement therapy (HRT)Medications like antidepressants can help with mood and depression Using lubricants for vaginal dryness Taking calcium and vitamin D supplements to help with weak bones.Lifestyle changes like exercising and eating a healthy diet  A few years post menopause, most symptoms should reduce and eventually stop. However, you should speak to your GP about troublesome issues and discuss treatments to manage menopausal symptoms.What Medication Can I Take for the Menopause?Menopause can produce a wide variety of symptoms affecting many aspects of physical and mental health. Some women go through menopause with no noticeable symptoms, while others have mild symptoms that they can manage with simple lifestyle adjustments. However, a number of women experience severe symptoms that disrupt their daily lives and require medication to reduce their impact.Oestrogel: Oestrogel is a topical hormone replacement therapy (HRT) that contains estradiol (i.e., oestrogen) as its active ingredient. This can counter the drop in hormone levels associated with menopause and help to alleviate symptoms like headaches, hot flashes, mood swings, heart palpitations, and more.Utrogestan: Utrogestan is a form of progesterone HRT. It should be used alongside an oestrogen-based HRT and can help to improve menopause symptoms by compensating for declining hormone levels.Estradot: Estradot is an HRT transdermal patch that contains estradiol, the primary form of oestrogen. The patches can be worn twice weekly to relieve hot flashes and night sweats, mood swings, vaginal dryness, and sleep problems.Evorel: Evorel HRT patches contain synthetic hormones that mimic the effects of oestrogen and progesterone. Users can apply the patches twice a week to rebalance hormones and improve menopause symptoms.Bijuve: Bijuve is an HRT medication containing both oestrogen and progesterone. These daily capsules supplement low hormone levels in menopause to relieve symptoms, including hot flushes, irritability, joint pains, and more.The hormonal changes brought about by menopause can manifest in diverse symptoms affecting many aspects of women’s physical, mental, and cognitive health. Prescription Doctor has a wide range of medications that can help to improve symptoms and quality of life by mitigating the effects of low oestrogen and progesterone levels.Support at Every StepIf you think you may be going through menopause or require some more advice, Prescription Doctor is here to help. Our dedicated team is available to support you at every stage, to help make the process as stress-free as possible.We strive to facilitate access to healthcare and give patients more control over how they obtain treatment. With us, there’s no need for face-to-face appointments that can take several days to arrange. Instead, you can fill out our online consultation form from your own home at any time. This makes obtaining a menopause test kit or ordering medication much more straightforward.Once the form has been completed, our specialist clinicians will review your information and determine whether your order is suitable for your circumstances. All orders approved before 3pm on a weekday are eligible for next-day delivery, while everything we dispatch is stored in plain packaging for complete discretion.To find out more about how Prescription Doctor can help you, or to request treatment, complete our consultation form today.  SourcesNIH (2024): What Is Menopause?PubMed (2023): Age at Natural Menopause and Influencing Factors in Women Attending the Gynaecological Outpatient Clinic at a Tertiary Care Hospital. PubMed (2025): Trends in age at natural menopause and menarche and related factors in Iran: results from a population-based study. NHS (2022): Menopause. BBC News (2024): What is the menopause and what are the main symptoms?NIH (2023): Menopause. NHS: Menopause for partners. NIH (2021): Hot Flashes: What Can I Do?Office on Women’s Health (2025): Menopause basics. Mayo Clinic (2024): Menopause. NIH (2021): Sleep Problems and Menopause: What Can I Do?PubMed (2022): Correlates of palpitations during menopause: A scoping review. British Heart Foundation (2023): Menopause and your heart. NHS Inform (2022): Menopause and your mental wellbeing. PubMed (2018): The Dynamics of Stress and Fatigue across Menopause: Attractors, Coupling and Resilience. PubMed (2025): Cognitive Function in Peri- and Postmenopausal Women: Implications for Considering Iron Supplementation. BUPA (2025): Does the menopause cause memory loss? Office on Women’s Health (2025): Menopause and sexuality. ScienceDirect (2024): Global prevalence of depression in menopausal women: A systematic review and meta-analysis. PubMed (2023): Does menopause elevate the risk for developing depression and anxiety? Results from a systematic review. Mayo Clinic (2023): The reality of menopause weight gain. PubMed (2023): Arthralgia of menopause - A retrospective review. BUPA (2024): Are muscle aches and joint pains linked to the menopause?PubMed (2021): Menopause and cognitive impairment: A narrative review of current knowledge. PubMed (2023): The Menopausal Transition: Is the Hair Follicle “Going through Menopause”?NICE (2021): Female pattern hair loss (female androgenetic alopecia). PubMed (2018): Dizziness in peri- and postmenopausal women is associated with anxiety: a cross-sectional study. NHS (2022): Menopause Symptoms. PubMed (2025): Urinary tract infections after menopause. Women’s Health Concern (2025): Digestive health and menopause. PubMed (2024): Taste Changes and Salivary Flow Rate Disparities in Premenopausal and Postmenopausal Women: Exploring the Zinc Connection. PubMed (2019): Urinary incontinence in postmenopausal women – causes, symptoms, treatment. PubMed (2024): The Link Between Menopause and Urinary Incontinence: A Systematic Review. PubMed (2025): The volume and characteristics of research on gastrointestinal symptoms in ‘natural’ peri- and postmenopause: A scoping review. PubMed (2024): The musculoskeletal syndrome of menopause. NIH (2025): Skin Care and Ageing. PubMed (2019): Estrogen-deficient skin: The role of topical therapy. Harvard Health Publishing (2023): Why has my natural scent changed during perimenopause?Shropshire Council: Menopause symptoms and practical tips to manage them. PubMed (2024): The Natural History and Risk Factors for the Development of Food Allergies in Children and Adults. PubMed (2015): Estrogen Signalling Modulates Allergic Inflammation and Contributes to Sex Differences in Asthma. PubMed (2023): Perimenopause as a neurological transition state. NIH (2025): Mastalgia. NIH (2024): Understanding Breast Changes and Conditions. UCI Health (2025): The surprising link between menopause and tinnitus. Tinnitus UK: Tinnitus and menopause. The Menopause Charity (2024): Join the dots: A-Z symptoms list.NIH (2022): Osteoporosis.  Victoria State Government: Menopause and osteoporosis. PubMed (2024): Menopause and Oral Health: Clinical Implications and Preventive Strategies. 
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What Are the 34 Symptoms of the Menopause?
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How to Lose Weight During the Menopause?

It is common for women to gain weight as they get older, especially during the menopausal phase. If you are going through menopause, you may find it challenging to lose weight now compared to before. To address this, consider taking a few proactive steps to make your weight loss efforts easier.What causes weight gain during menopause?There are several factors that contribute to weight gain in women during menopause.Change in hormone levelDuring menopause, oestrogen levels in women start to drop gradually. This causes the body to store more fat than before, especially around the midsection areas.Natural ageingAs people age, they typically become less active, and their metabolism slows down accordingly. These factors combined cause a reduction in muscle mass, making it easier for the body to store more fat.Poor sleepWomen experience symptoms like hot flashes and night sweats during menopause, which can cause sleep deprivation. A lack of high-quality sleep over time can lead to weight gain.Gaining weight around the waistline and especially at menopausal age can increase your risk of certain conditions like diabetes, heart disease and cancer. Therefore, it is important to address weight gain during menopause as soon as possible.Weight loss tips during menopauseIt may be more challenging to lose weight during menopause because of age and hormonal changes, but there are some strategies you could use to help you beat weight gain during this phase.Increase physical activityNatural ageing and menopause can slow down your body’s metabolism over time. A good way to address this is to increase your physical activity levels, ensuring that you incorporate exercises that build muscle and reduce body fat, such as resistance training and weightlifting exercises.Eat healthy meals A vital part of losing unhealthy weight requires you to eat fewer calories than your body needs daily. You can start with weekly meal planning and avoiding junk food, which mainly contains unhealthy (empty) calories. You should always aim to eat and fill up on healthy portions of food with fewer calories, such as whole grain foods, protein, fruits, and vegetables.Join weight loss groupsWeight loss groups offer support and accountability to help you achieve and maintain your weight loss goals. The NHS offers a free 12-week weight loss plan, complete with weekly diet and exercise goals, as well as an online weight loss community to support you throughout the process.Make key lifestyle changesIn addition to losing unhealthy weight, you should also plan to maintain your weight loss in the long term. Making certain lifestyle changes can help you maintain the weight loss over time. For example, you can quit smoking, reduce your alcohol intake to moderate levels, drink more water every day and ensure you get good quality sleep at night.Consider additional methodsIn addition to healthy lifestyle changes, there are weight loss pills that can help to reduce fat storage in your body. However, it is important to always consult with your GP first, and remember that weight loss pills are only effective with a healthy diet.
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How to Lose Weight During the Menopause?
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How Long Does the Menopause Last?

Menopause is a natural part of a woman’s life, and you can expect your experience to differ from other women.As women approach their 40s and 50s, their periods become less frequent until they eventually stop, and they are unable to become pregnant naturally. This process leads to the menopause.Read more: 10 questions about the menopause answeredWomen go through the natural process of menopause in three stages:PerimenopauseIn this phase, your body begins to produce fewer eggs from your ovaries and less oestrogen, causing irregular periods. Some women experience shorter or longer menstrual cycles, as well as lighter or heavier periods. The most common symptoms women have during perimenopause are hot flushes, night sweats, vaginal dryness and reduced sex drive.MenopauseMenopause actually refers to the point in time when you have had no periods back-to-back for exactly one year. In the UK, the average age for a woman to reach menopause is 51 years.Post-menopauseWomen who have stopped having their periods for at least one year will be referred to as postmenopausal for the rest of their lives. Most symptoms of menopause will reduce in this phase but some women may still experience a few symptoms like hot flushes, sleep problems, joint pains and vaginal dryness for a few more years.The exact timing of these stages varies from one woman to another.Several factors can influence the timing and severity of menopause symptoms.Lifestyle factorsCertain lifestyle factors can cause women to experience menopause earlier than others. For example, women who are stressed, overweight and smoke are more likely to have an early menopause, which usually happens before they’re 45 years old.However, positive lifestyle factors like regular exercise and maintaining a healthy weight help improve menopausal symptoms of low mood and sleep problems.GeneticsThe genetic makeup of some women causes them to experience menopause in their late 30s. This is referred to as premature ovarian failure, not premature menopause. Usually, knowing when your mother and grandmother started menopause may provide a rough guide as to when you are likely to begin your menopause phase.Women born with genetic conditions like Turner syndrome and Fragile X syndrome have ovaries that don’t function properly, causing them to have premature menopause.Medical conditionsAutoimmune diseases like rheumatoid arthritis and thyroid disease cause the body’s immune system to attack and damage organs like the ovaries, causing women with these conditions to begin menopause prematurely.Medical interventionsMedical interventions, such as hysterectomy or chemotherapy that result in the removal of or damage to the ovaries, can cause menopause to begin suddenly, rather than follow its natural, gradual progression.How long does menopause last?Menopause symptoms usually last anywhere from 2 to 10 years; however, most women take about 4 years to reach menopause.As a general guide, you have reached menopause when 12 months have elapsed since your last period.Going through menopause prematurely or suddenly can cause uncomfortable and distressing symptoms to begin within a shorter time frame compared to a natural menopause.Your doctor can advise you on how to manage your symptoms to help you with the transition to post-menopause.
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How Long Does the Menopause Last?
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Can You Get Your Period While On Utrogestan?

Menopause is one of the most pivotal events of a woman’s life, affecting people both physically and mentally. Medication is available to help with symptoms and support your body as you navigate the changes ahead, but which one is right for you?Utrogestan is one such option. Known as micronised progesterone, it has been proven effective for symptoms such as hot flushes, night sweats, and sleep disturbances. However, because everyone reacts to medication differently, the fact that a treatment can have a positive impact doesn’t mean it’s suitable in all cases. Doing your research is essential.An important element of this research is whether or not you can menstruate while taking the medication. So, can you get your period while on Utrogestan? That’s what this article will explore.   [medical_form product_id="131" text="START YOUR CONSULTATION TODAY" type="button"] What Does Utrogestan Do?Utrogestan 100 mg capsules contain a plant-based form of progesterone, the female sex hormone that prepares the body for pregnancy. The progesterone in Utrogestan is identical to the progesterone the body makes before menopause.During and after the menopause, oestrogen and progesterone levels fall, causing the common menopause symptoms. Hormone Replacement Therapy (HRT), such as Utrogestan, helps replace declining hormone levels to improve your quality of life and provide relief.Women who take HRT and have their womb intact need to take a progesterone HRT and an oestrogen one. However, because oestrogen causes the womb lining to grow, Utrogestan causes it to shed, preventing the lining from building up and lowering associated risks. You can learn more about the uses of Utrogestan in our dedicated article. What’s the Usual Utrogestan Dose?How much Utrogestan you’ll be prescribed will depend on where you are in your menopause journey. If you are still having periods, or you’ve had one within the last 12 months,  the usual prescription is two 100 mg capsules taken together in the evening. These are taken from day 15 to day 26 of your HRT cycle.If you have not had a period for more than a year, the usual dose is one 100 mg capsule every evening without a break. For information about how long it takes Utrogestan to work, read our guide.   What are the Advantages of Utrogestan?One of the major advantages of Utrogestan is that it is plant-derived and body-identical, meaning it is identical to the progesterone your body naturally produces. Women who take Utrogestan are less likely to experience side effects compared to other, more traditional types of progesterone HRT.There is strong evidence that micronised progesterone-like Utrogestan does not increase the risk of blood clots, unlike other older progesterone HRT options. Utrogestan may also be associated with a lower risk of breast cancer compared to other forms of progestogen HRT.Why Understanding the Impact of HRT on Menstruation is ImportantHaving a clear indication of whether you can have a period while taking HRT medication is essential for a number of reasons. These include:Safety and Monitoring: Unscheduled bleeding while taking HRT can sometimes be a sign of a medical issue that needs looking into, such as endometrial hyperplasia or endometrial cancer in rare cases. Need for Contraception: HRT medication doesn’t act as a contraceptive or impact fertility, so it’s still possible that you could become pregnant. The treatment can also mask or alter bleeding patterns, so there’s a risk you may not realise that you’re still ovulating. According to the NHS, you should continue to use contraception for at least 1 year from your last period if you’re over 50 years old, or 2 years if you’re under 50. Managing Treatment: Persistent unscheduled bleeding can be a sign that your HRT programme should be reviewed and potentially adjusted. Investigation is recommended if bleeding persists for more than 3 months. Can You Get Your Period While on Utrogestan?Utrogestan doesn’t cause you to have a period, but it may make you bleed, which looks similar to a period. Utrogestan is a type of progestogen HRT that’s suitable for women who still have their wombs and should be taken alongside oestrogen replacement therapy.That’s because oestrogen causes your womb lining to thicken, so taking Utrogestan helps shed your womb lining. For this reason, many women experience some bleeding, similar to a period, at the end of each cycle.This is called a withdrawal bleed, and it's completely normal – it happens because your progesterone levels drop when you stop taking Utrogestan for those few days. The bleeding is usually lighter and shorter than a natural period, though this can vary from woman to woman. {add_product_block(131)} Does Utrogestan Stop Periods?Not exactly. Utrogestan doesn't stop your periods in the way that contraception might, but the type of HRT regimen you're on will affect whether or not you bleed.If you're on a sequential regimen (taking Utrogestan for part of each month), you'll usually have a withdrawal bleed after you finish each course of capsules. This is normal and expected – it's your womb lining shedding in response to the drop in progesterone.If you're on a continuous regimen (taking Utrogestan daily), you shouldn't experience regular bleeding once your body adjusts. Some women experience spotting or irregular bleeding in the first 3 to 6 months, but this usually settles down. If it doesn't, speak to your doctor.When Do You Bleed on Utrogestan?When you bleed depends on which HRT regimen you've been prescribed. On a sequential regimen, bleeding typically happens in the few days after you stop taking Utrogestan each cycle – so if you take your capsules on days 15 to 26, you'd usually bleed around days 27 or 28 onwards. This is called a withdrawal bleed and is similar to a period, though it may be lighter or shorter than what you were used to before menopause.On a continuous regimen, you may have some irregular bleeding or spotting during the first few months as your body adjusts. After that, most women find that bleeding stops altogether.Will I Experience Heavy Bleeding on Utrogestan?Some women do experience heavier bleeding than expected when they first start Utrogestan, particularly during the first 3 to 6 months of treatment. This is common as your body adjusts to the new hormone levels and usually settles with time.However, if your bleeding is consistently heavy, lasts longer than expected, or happens more than once a month, you should speak to your doctor. They may need to adjust your Utrogestan or oestrogen dose to find the right balance. In some cases, your doctor may want to investigate further to rule out other causes – particularly if heavy or unexpected bleeding continues beyond 6 months of starting HRT.What is Utrogestan Breakthrough Bleeding?Breakthrough bleeding is any bleeding that happens outside of your expected withdrawal bleed – for example, mid-cycle spotting or bleeding on days when you're still taking your capsules. It's one of the most common side effects when starting HRT, and while it can be a nuisance, it's usually not a cause for concern.Breakthrough bleeding occurs as your body adjusts to new hormone levels. It can also occur if you've missed a dose, changed your oestrogen dose, or started taking Utrogestan at a different point in your cycle. Most women find that breakthrough bleeding settles within the first 3 to 6 months of treatment.If breakthrough bleeding persists, your doctor may suggest adjusting your progesterone dose or extending the number of days you take Utrogestan each cycle. If you experience any bleeding after you've been on HRT for more than a few months and it was previously settled, contact your doctor – they may want to investigate further to be safe.  No Withdrawal Bleed on Utrogestan: Is This Normal?Yes – it's perfectly normal not to have a withdrawal bleed every cycle, and it's nothing to worry about as long as there's no chance of pregnancy. Not every woman bleeds at the end of each course of Utrogestan, and some months you may bleed more lightly than others, or not at all.If you're taking Utrogestan on a continuous regimen (every day), bleeding is expected to stop once your body adjusts to the medication. On a sequential regimen, a missed withdrawal bleed occasionally is also common – it simply means there wasn't much womb lining to shed that cycle.However, if you're concerned or if you've had a sudden change in your bleeding pattern after being settled on HRT for several months, it's always worth checking in with your doctor for reassurance.Frequently Asked QuestionsHave questions about bleeding and periods while taking Utrogestan? Here are answers to the most common questions women have about HRT.Should I Take Utrogestan 100 mg Capsules With or Without Food?Utrogestan 100 mg capsules should ideally be taken with food to increase bioavailability. It is worth pointing out that doing so can increase blood levels and enhance the risk of drowsiness, which is why most women find it easier to take Utrogestan just before bed.Is Utrogestan a Contraceptive Pill?No, Utrogestan is not a contraceptive pill, and it is possible to get pregnant while you are taking HRT. To prevent pregnancy, you will need to use contraception until 2 years after you have your last period if you’re under 50 or for one year if you are over 50.If you're looking for contraceptives, Prescription Doctor has a range of options. These range from the combined pill and mini-pill, through to the morning-after pill. and contraceptive ring.  Are There Alternatives to Utrogestan?Prescription Doctor offers a range of menopause treatments as alternatives to Utrogestan. These include:Provera: A type of progestogen HRT that contains medroxyprogesterone acetate as its active ingredient.Veoza: A non-hormonal menopause treatment that may be suitable for women who cannot or choose not to take hormonal methods. However, it is not specifically licensed for all menopausal symptoms. Evorel Conti: A continuous combined hormone replacement therapy which contains man-made versions of oestrogen and progesterone. Evorel Conti is supplied as a patch and is worn on the skin rather than taken as a pill.Bijuve: A combined oral capsule that contains both oestradiol and micronised progesterone in one pill, designed for postmenopausal women who want body-identical HRT without taking two separate medications.Some women may also use a Mirena coil as an alternative way of receiving progestogen as part of HRT – speak to your GP about whether this is suitable for you.Specialist Support You Can Rely Upon If you’re going through menopause or experiencing symptoms, you may find it helpful to feel you have a strong support network at your disposal when you need advice or are unsure of the best course of action. This is where Prescription Doctor can help.  Our service is designed to provide help and guidance whenever it is needed. We start with a simple online consultation where you provide details about your medical history and any other treatments you may be taking. The information is then reviewed by our experienced clinicians to determine whether your chosen medication is suitable for your circumstances. Once approved, the item is dispatched by our General Pharmaceutical Council-registered pharmacy in discreet packaging.We will then regularly check in with you to monitor progress and ensure everything is working as planned. You can also contact the team if you have any questions about your treatment plan, and our clinicians will be happy to help. We are here for the whole journey.Ready to get started? Begin a consultation with Prescription Doctor today. SourcesPubMed (2018): Progesterone for the treatment of symptomatic menopausal women.NHS: How and when to take Utrogestan.NHS: Side effects of Utrogestan.EMC (2024): Utrogestan 100mg Capsules – Summary of Product Characteristics.BMS (2022): Progestogens and endometrial protection.NHS: Types of hormone replacement therapy (HRT).British Menopause Society (2024): Management of unscheduled bleeding on hormone replacement therapy (HRT). NHS (2023): Pregnancy, breastfeeding and fertility while taking or using sequential combined hormone replacement therapy (HRT). CoSRH (2025): Contraception for Women Aged Over 40 Years.
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Can You Get Your Period While On Utrogestan?

Treatment information

  • Product Name: Utrogestan
  • Manufacturer: Besins Healthcare
  • Active Ingredient(s): Progesterone
  • Administration: Oral
  • Presentation: Soft, white capsules
  • Available Strength: 100 mg
  • Exemption: Prescription Only
  • Application: Postmenopausal women
  • Dosage: 200 mg daily
  • Description: A hormone replacement therapy for postmenopausal women
  • Drug Class: Progestogen
  • Alcohol Consumption: Can drink alcohol, but avoid or reduce intake if it exacerbates side effects such as tiredness, flushing, dizziness, or worsens sleep. 
  • When Pregnant: Do not consume. Speak to your doctor for further advice.
  • When Breastfeeding: Do not consume. Speak to your doctor for further advice.
  • Price: 32.99 GBP
     
Click here to view the Utrogestan - Patient Information Leaflet

Authored By

Leanne

Leanne Edermaniger

Medical Content Writer
Leanne is a science and health content writer focusing on human health and biology while utilising her solid academic background.

Published on: 28/02/2019 Re-Published on: 18/05/2026

Reviewed By

Mohamed Imran Lakhi

Mohamed Imran Lakhi

MPharm - Lead Pharmacist
Imran Lakhi is the superintendent pharmacist and founder at Prescription Doctor. He has been at the core of our team.

Reviewed on: 18/05/2026

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