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Oestrogel

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About Product
This content has been written and checked for quality and accuracy by
Mohamed Imran Lakhi Content Administrator GPhC: 2060586 Updated on: 06/11/2020 Next review: 06/05/2021

Buy Oestrogel Online

With Prescription Doctor's trusted online pharmacy, you can buy Oestrogel hormone replacement therapy (HRT) for the menopause following a short online consultation with one of our doctors.

Oestrogel is available in a convenient 80g pump which delivers a specific amount of gel with each actuation. If you have had your womb removed in a surgery called a hysterectomy, you can use Oestrogel on its own. However, women who have not had their womb removed will need to take another HRT which contains progestogen to counter the effects of the estradiol found in Oestrogel.

To begin your order, simply fill out our medical form for our doctor to review. If your order is approved before 3pm, Monday to Friday, our UK based GPhC registered pharmacy will dispense and dispatch your item the same day via a next-day discreet delivery service.

Do I need HRT if I am going through the menopause?

The menopause is an inevitable event in life. It is marked by the end of menstruation and signals the end of fertility, meaning you can no longer become pregnant through natural means.

Most women experience the menopause in their 40s and 50s, though premature menopause can occur in women whose ovaries have stopped working (premature ovarian failure) or have been surgically removed (typically removed with the womb during a hysterectomy. The symptoms of the menopause can last for between 2 and 10 years, though most women reach the menopause in 4 years.

If you are unsure whether you are going through the menopause, speak to your doctor.

You can also buy a home menopause testing kit online, such as the SelfCheck Menopause Test, available from Prescription Doctor.

The menopause is caused by a drop-off in the amount of oestrogen levels in women. Oestrogen is a female sex hormone which is produced in the ovaries, and plays a number of roles in the female body.

Importantly, oestrogen can help prevent osteoarthritis in women. A drop of oestrogen levels has been linked to an increase in bone resorption - the process of breaking down bone to release minerals into the blood stream - and an increase in the delay between the breakdown of bone and the formation of new bone. This weakens bone over time, contributing to bone disorders such as osteoarthritis.

This fall of oestrogen in the body causes a number of symptoms including:

  • Decreased libido (low sex drive)
  • Decreased muscle mass
  • Headaches
  • Hot flushes
  • Joint and muscle pain
  • Memory and concentration problems
  • Mood swings
  • Night sweats
  • Palpitations
  • Recurrent urinary tract infections
  • Sleep problems
  • Vaginal dryness

For some women, the symptoms may be manageable, while other women may find the symptoms disruptive to their daily life. As such, it's important to speak to your doctor if your symptoms are causing you distress.

Your doctor may be able to prescribe a suitable HRT for you, based on your medical history and considering any other medications you may be taking. You should always speak to your doctor before you buy HRT online to ensure that it is safe for you.


What is Oestrogel?

Oestrogel is a hormone replacement therapy (HRT) for menopausal women. It relieves unpleasant symptoms by replenishing the body with the hormones which drop off during the menopause.

By countering this drop of hormone levels, the symptoms are assuaged.

Oestrogel is a topical gel which is dispensed in metered doses from a pump. The pump ensures that each dose is equal, as it only allows a specific amount of gel out.


How do I use Oestrogel?

Oestrogel is dispensed from a pump and contains 750 mcg of estradiol per actuation. The gel is spread over a large surface area where it is then absorbed through the skin.

What you need to know before using Oestrogel

If you have not used an HRT medicine before, or are switching from period-free HRT treatment, you can start using Oestrogel whenever is most convenient for you.

If you are already using a type of HRT in which you have a period, finished the medicine pack of your current HRT before you start using Oestrogel.

You must apply the gel yourself. Do not let anyone else apply the gel for you.

After applying the gel, avoid close skin to skin contact with your partner for 1 hour after.

Do not wash or apply skin care products to the area of skin the gel is applied to for 1 hour after applying it.

Before you use Oestrogel pump for the first time, it's important to prime your pump. This ensures that the medicated gel is dispensed from your pump correctly and ensures the right amount of gel is dispensed.

To prime Oestrogel pump:

  1. Remove the cap from the canister
  2. Remove the stopper from the spout
  3. Depress the plunger a couple of time until the gel is expelled
  4. Do not use this initial dose. Discard of it safely using a tissue.

Once your pump is primed, it is ready to use.

Using Oestrogel

To use Oestrogel pump:

  1. Remove the cap to reveal the plunger.
  2. While holding the canister in one hand and readying your other hand to catch the gel, depress the plunger to expel one measure of the gel. If your doctor has prescribed more, use the amount of gel prescribed by your doctor.
  3. Apply the gel to your outer arms and shoulders, or the mid-inner thigh of both legs. Do not apply Oestrogel to the genital area or breasts.
  4. Spread the gel over the area.
  5. Cover the spout with the included stopper and replace the cap.
  6. Wait 5 minutes for the area to dry before covering it with clothes.
  7. Always wash your hands with soap and water after using Oestrogel.

You should try to apply Oestrogel at the same time everyday.

If the prescribed amount does not relieve your symptoms, speak to your doctor.

Do not use more or less gel than prescribed without first consulting your doctor.


Side effects and cautions

You should always read the enclosed patient information leaflet before using Oestrogel for the first time. This leaflet contains important information about the medicine, including how to use and store Oestrogel safely.

You can read the patient information leaflet for Oestrogel online here.

If you have any concerns about any of the information found within the patient information leaflet, speak to your doctor or ask a pharmacist for assistance.

Contraindications

Oestrogel is not suitable for everyone. It's important to speak to your doctor before you buy Oestrogel to ensure that it's safe for you.

Do not take Oestrogel if you:

  • are allergic to estradiol or any of the other ingredients listed in the patient information leaflet;
  • have a blood clotting disorder (such as protein C, protein S or antithrombin deficiency);
  • have a rare inherited blood disorder called porphyria;
  • have any unexplained vaginal bleeding;
  • have cancer which is sensitive to oestrogens, such as endometrial cancer;
  • have excessive thickening of the womb lining (endometrial hyperplasia) which is untreated;
  • have or have ever had a blood clot, including in the vein (thrombosis), legs (deep vein thrombosis/DVT) or lungs (pulmonary embolism);
  • have or have ever had a liver disease and your liver function tests have not returned to normal;
  • have or recently had a disease caused by a blood clot in the arteries, such as a heart attack, stroke or angina;
  • have, had or are suspected to have breast cancer.

Some medicines can interfere with the effects of Oestrogel. It is important to inform your doctor of any and all medicines you are currently taking, including those bought over the counter such as health and herbal supplements.

Inform our doctor if you will be using any of the following medicines while using Oestrogel:

  • Epilepsy medicines (phenytoin, phenobarbital or carbamazepine)
  • HIV medicines (nevirapine, efavirenz, ritonavir or nelfinavir)
  • Herbal products contains St John's Wort (hypercium perforatum)
  • Other medicines which affect how skin is made (e.g. anti-cancer products)
  • Other skin products containing alcohol, including astringents or sunscreens
  • Products used to treat warts, acne, dandruff or other skin and scalp conditions
  • Skin cleansers containing benzalkonium chloride or sodium lauryl sulphate
  • Tuberculosis medicines (rifampicin, rifabutin)

If you are unsure whether Oestrogel is safe for you, speak to your doctor or a pharmacist.

Your doctor will be able to determine the safety of Oestrogel based on your medicine history and.

Side effects

All medicines have the potential to cause side effects, though not everybody who takes Oestrogel experiences side effects. It's important to familiarise yourself with the potential side effects of your medicine before you take it.

While using Oestrogel, you should remain vigilant of side effects which can develop.

Common side effects (may affect up to 1 in 10 people):

  • Abnormal or irregular bleeding
  • Menstrual periods which are heavier or last longer than usual
  • Painful periods
  • White or yellow vaginal discharge

Uncommon side effects (may affect up to 1 in 100 people):

  • Feeling of weakness
  • Increase in the volume of the uterus
  • Migraine
  • Mood swings
  • Vaginal yeast infection (candidiasis)
  • Vertigo
  • Wind (flatulence)

Rare side effects (may affect up to 1 in 1,000 people):

  • Intolerance to glucose, which may affect your blood sugars
  • If you have epilepsy, your symptoms may worsen
  • High blood pressure
  • Changes in liver function
  • Acne
  • Unusual production of breast milk
  • Anaphylaxis (severe, acute allergic reaction)

This is not a complete list of side effects. Further information regarding the safety of Oestrogen, including a complete list of side effects, can be found within the patient information leaflet which comes enclosed with your treatment.

If you experience any side effects while using Oestrogel, regardless of whether they are listed above or in the patient information leaflet, inform your doctor or speak to a pharmacist for assistance.

Allergic reaction

Do not use Oestrogel if you are allergic to estradiol or any of the other ingredients listed in the patient information leaflet.

If you experience the signs and symptoms of an allergic reaction, stop using Oestrogel and seek immediate medical attention by going straight to your nearest accident and emergency department. Remember to take the packaging leaflet and any remaining medicine with you - this is so that doctors can ascertain exactly what you have taken.

Signs of an allergic reaction can include:

  • Chest tightening
  • Dry, red and cracked skin
  • Itchy, red, watery eyes
  • Raised, itchy, red rash (hives)
  • Swelling of the face, lips, tongue and throat
  • Tummy pain, nausea, vomiting or diarrhoea
  • Wheezing or difficulty breathing

Pregnancy and breatfeeding

Oestrogel is only indicated for postmenopausal women.

Do not use Oestrogel if you are pregnant or breastfeeding.

If you become pregnant while using Oestrogel, stop using the treatment seek advice from your doctor.

Other safety information

Always speak to your doctor before you buy Oestrogel from Prescription Doctor.

Do not use Oestrogel past the expiry date printed on the packaging. The date refers to the last day of the specified month.

Never throw away medicine via household or water waste. Take any unwanted or expired medicine to your local pharmacy and ask them to dispose of it safely on your behalf.

Always store medicine out of sight and reach from children and pets.

Never share your medicine with anybody else, even if they are experiencing the same symptoms or have been diagnosed with the same condition as you.


Frequently asked questions

What should I do if I forget to use Oestrogel when I should?

If it is more than 12 hours until your next dose of Oestrogel, apply the gel as soon as you remember and apply your next dose at the usual time.

If it is less than 12 hours until your next dose of Oestrogel, skip the missed dose and apply the next dose at the usual time.

Missing a dose of Oestrogel may result in breakthrough bleeding or spotting.

Do not use more Oestrogel to make up for the dose you missed.

What should I do if I accidentally apply more Oestrogel than I should?

Oestrogel is dispensed in a metered dose. You should only use as many pumps of Oestrogel as prescribed. Using more Oestrogel than you should can cause signs of an overdose including breast tenderness, nausea and vaginal bleeding.

Using more Oestrogel than you should will not cause your symptoms to go away faster, but can increase your risk of side effects and overdose.

If you find that the prescribed amount of Oestrogel is not relieving your symptoms, speak to your doctor. Do not adjust your dosage unless your doctor has given you explicit permission to do so.

Can I drink alcohol while using Oestrogel?

You should drink alcohol in moderation when using Oestrogel. Do not drink more than the recommended 14 units per week.

Will Oestrogel impact my ability to drive or operate machinery?

Oestrogel is unlikely to interfere with your ability to drive or operate machinery.

Will Oestrogel interfere with my contraception?

Oestrogel is not a contraceptive. If it has been less than 12 months since your last period, or you are under the age of 50, you may need to use additional contraception to prevent pregnancy.

Oestrogel may interfere with some contraceptives. It's important to speak to your doctor about using contraceptive while using Oestrogel.

How long does Oestrogel take to work?

It can take a few weeks of using HRT before the effects become noticeable, and a further few months before the treatment reaches peak effectiveness.

When is the best time of day to apply Oestrogel?

You can apply Oestrogel at any time of day which suits you. If you often forget when to use Oestrogel, set a reminder on your phone or store your Oestrogel in a location which is likely to to jog your memory.

How do I know if I run out of Oestrogel?

You will know when your Oestogel pump has run out when you press down the plunger and it doesn't return up to its normal position.

If this happens, you should stop using that pump and start a new pump.

How long does 1 Oestrogel pump last?

How long an Oestrogel pump lasts will depend on your dosage. For the usual daily dose of 2 measures, the pump should last 4 weeks. If your doctor has prescribed 4 measures, the pump should last 2 weeks.

What if I think I've transferred Oestrogel onto someone else?

If you think you've transferred Oestrogel onto someone else, such as a man or a child, wash the area of skin the gel may have been transferred to with soap and water immediately.


Sources

NHS, 2018. Menopause

Besins Healthcare (UK), 2019. Oestrogel Pump-Pack 750 micrograms/actuation Gel: Summary of Product Characteristics

Treatment information

  • Product Name: Oestrogel
  • Manufacturer: Besins Healthcare (UK) Ltd
  • Active Ingredient(s): Estradiol
  • Administration: Topical
  • Presentation: Gel
  • Available Strength: 750 mcg/actuation
  • Exemption: Prescription-only
  • Dosage: Apply 2 measures to either the upper arms and shoulders, or the mid-inner thigh.
  • Description: Oestrogel is HRT for post-menopausal women which is applied topically.
  • Drug Class: Hormonal replacement therapy (HRT)
  • Alcohol Consumption: No influence
  • When Pregnant: Do not use Oestrogel during pregnancy. Speak to your doctor for further advice.
  • When Breastfeeding: Do not use Oestrogel if you are breastfeeding. Speak to your doctor for further advice.
Click here to view the Oestrogel - Patient Information Leaflet

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