Wegovy Pill

There are plenty of weight loss medications available in the UK, with two of the most prominent injections being Mounjaro and Wegovy. While coming from different manufacturers, they both work similarly towards the same goal: to manage and reduce weight.The two treatments have similar side effects, and both have the same eligibility criteria: a BMI (Body Mass Index) of ≥ 30 or ≥ 27 if you have at least one weight-related health issue. They’re both GLP-1 (glucagon-like peptide-1) agonists, this being the hormone they target within the body that allows for weight loss, though Mounjaro also targets GIP (glucose-dependent insulinotropic polypeptide). In many ways, Mounjaro and Wegovy don’t seem to differ much, and switching from one to the other may be due to side-effect severity or ingredient allergies.However, in 2026, the Wegovy pill became widely available, offering a third option to those who dislike needles/injections. It’s the first GLP-1 pill to be approved by the MHRA, giving it a ‘best of both worlds’ appeal - the accessible administration of an oral pill, and the high rates of weight loss Wegovy is known for. If you’re considering switching from Mounjaro to Wegovy pills, this article will cover any questions or concerns you may have. [medical_form product_id="476" text="START YOUR CONSULTATION TODAY" type="button"] Can I Switch From Mounjaro to Wegovy Pills?Yes, you can switch from Mounjaro to Wegovy pills if you feel it would be beneficial for your weight loss journey. For example, you could be showing low rates of progress with tirzepatide (Mounjaro’s active ingredient), having difficulty managing side effects, or feeling more comfortable with the idea of taking an oral tablet instead of injecting yourself.Whatever your reasons, it’s essential that you seek clinical advice before making any changes to your medications. This is to ensure that your new treatment is safe and suitable for your circumstances. It also helps you get a good idea of what your new regimen and routine will look like, giving you the best possible chance of making a positive start.Switching from Mounjaro to Wegovy pills means moving from injectable tirzepatide to oral semaglutide (Wegovy’s active ingredient) and adapting to a brand-new treatment routine and dosage schedule. Exactly where you start will depend on several factors, such as your current Mounjaro dose, how well you are tolerating it, your weight loss progress, and when you last took your dose.   How Do the Mounjaro Injections and Wegovy Pills Work?To understand the process of switching between the two treatments, we must first understand how they both work, their similarities and their differences.Mounjaro InjectionsMounjaro is a subcutaneous (under-the-skin) injection that is taken on the same day each week. It can be administered at any time of day and does not require an empty stomach. It contains the active ingredient tirzepatide, a ‘dual agonist’ that targets two hormones in the body rather than one - these being GLP-1, the same as Wegovy, and GIP. This additional hormone gives it an edge over Wegovy by making the treatment much more effective.Since it’s injected under the skin, the medicine can enter your bloodstream straight away with relative ease. The Mounjaro in your system will decrease your appetite and slow down digestion in your stomach. This results in you eating less and consuming fewer calories, which makes other healthy lifestyle changes more effective. It also lowers blood sugar levels.In trials, it has shown an average 22.5% reduction in body weight. It is the only dual agonist available in the UK.Wegovy PillsBy comparison, Wegovy is a daily pill to be taken after an eight-hour fast, which for most will be after a night’s sleep. After swallowing it with water, an additional 30-minute fast is required to allow it to dissolve in your system. The pill is coated with a protective layer of Salcaprozate Sodium and Magnesium Stearate, so it cannot be taken crushed, split, or chewed, as this will damage the protective coating it needs to be absorbed correctly.Wegovy’s active ingredient is semaglutide, and it has essentially the same effect as Mounjaro’s: suppressing appetite, slowing digestion, and lowering blood sugar, just to a less effective degree since it’s a ‘solo agonist’, only targeting the GLP-1.In trials, it has shown an average 13.6% reduction in body weight. It is the only GLP-1 pill available in the UK.  Why Should I Switch from Mounjaro to Wegovy Pills?There are several reasons why the choice to move from Mounjaro injections to Wegovy pills could be made, including:AdministrationA common reason to switch is a dislike of needles. Not a fear necessarily, but many patients aren’t keen on needles, or are understandably squeamish about them, especially when it comes to injecting their own body. A pill is much more straightforward and accessible, and with less room for user error.Taking an injection once a week may lead some users to dread that upcoming day or forget about it entirely as it comes around less frequently. A daily pill may fit into your routine a lot better than a weekly injection.IngredientsSince Mounjaro and Wegovy contain different ingredients, people will have different reactions to the two treatments. Some may suffer more severe side effects with one, whereas others may find that one is simply less effective than the other. If you find the Mounjaro side effects to be a struggle, you may be better suited to Wegovy pills.Furthermore, the two treatments may interact with other medications you may be taking. For example, Mounjaro can make diabetes medications too effective, lowering blood sugar levels to dangerous amounts.Secondary BenefitsMounjaro doubles as a type 2 diabetes treatment, while Wegovy doubles as a medication to reduce the risk of certain cardiac events for those who are vulnerable to them, such as strokes and heart attacks. Depending on your medical history, this may also serve as a reason to switch or stay. {add_product_block(476)} ContraceptivesWegovy has no proven impact on the effectiveness of contraception, while Mounjaro does. Oral contraceptives like progestogen-only or combined pills may be drastically less effective while taking Mounjaro, but because of the different active ingredient, there has been no evidence that Wegovy pills interact with contraceptives in any way.CostWegovy pills are cheaper than Mounjaro injections, and the ratios of price to dosages can be seen here:  Overall, the Wegovy treatment is considerably cheaper than Mounjaro, especially in the long term. This could be another reason to switch; however, it should not be the only reason - you must undergo the treatment that works best for you.How do I Switch from Mounjaro to Wegovy Pills?Switching from Mounjaro to Wegovy pills is a simpler process than many expect. Speaking with your clinician will always be the first step; nothing can happen without their professional approval. They will address how the Mounjaro treatment is working for you, considering a range of factors.If your clinician agrees that Wegovy may be better suited to you, then your first Wegovy pill can be taken on the same day as your next Mounjaro injection should have been. This will typically be at least seven days after your last one, to ensure the Mounjaro has enough time to substantially leave your system by the time you start the pills, since having two medications affecting you in the same way can cause worsened side effects. Again, your clinician will guide you through this.What Should I Expect After Switching to the Wegovy Pill?Everyone’s weight loss journey is different, so everyone’s experience switching from Mounjaro to Wegovy pills will be different, too. However, there are commonly seen effects you may experience.Since a full seven days between stopping injections and starting pills is required to allow the Mounjaro to be mostly removed from your system, you may see an increase in appetite again. This will quickly settle back down once on Wegovy, and it is important to exercise restraint during this time to avoid losing weight loss momentum. Keep up your healthy diet and regular exercise, and keep your weight loss goals in mind to help see you through.You may need to re-adjust to side effects. Starting any new treatment, even one so similar, can cause significant side effects. You may see an initial spike in severity, but once your body is used to Wegovy, the effects should settle down. Your clinician will recommend a lower starting dose if they feel side effects may cause an issue for you, helping to create a smoother transition.After adjusting to the Wegovy treatment, you should notice a more comfortable feeling in your body, a more effectively suppressed appetite, and a reduction in both quantity and severity of side effects. This will show that the transition to Wegovy has been successful. If few or none of these occur, your clinician may recommend a switch back to Mounjaro, or an alternative weight loss treatment, such as Mysimba or Nevolat.Will My Dosage Stay the Same After Switching from Mounjaro to Wegovy Pills?Mounjaro and Wegovy are measured in different doses, so there is no universal 1:1 conversion to determine your starting point with Wegovy tablets.The Wegovy pill dosage you switch to will be assessed by your clinician based on your prior progress and experiences with Mounjaro dosages, as well as how well you responded to them. An idea of how the doses may transfer is below, though this can differ case by case:  As stated, these measurements are subject to change and vary by individual. Your clinician will decide which Wegovy dosage is right for you based on several factors, including the severity of side effects and weight loss progress. If the Mounjaro injections have led to you struggling with side effects, you may be placed on a lower dosage of Wegovy to ease your body into the new medicine.How Effective is the Wegovy Pill Compared to Mounjaro?In clinical trials, the Wegovy pill is consistently less effective than Mounjaro injections. In a 72-week trial, the highest dose of Mounjaro reduced body weight by an average of 22.5%, while in other trials, the highest dose of Wegovy pill reduced body weight by an average of 13.6% in 71 weeks. Wegovy injections fall somewhere in the middle, around 14.9% in 68 weeks.  However, as stated earlier, there are many reasons you may favour Wegovy over Mounjaro, despite the lower average weight loss. It is important to research all aspects before starting or switching your treatment, and Prescription Doctor is here to answer any queries you may have.What are the Side Effects of the Wegovy Pill?Since Mounjaro and Wegovy contain different active and passive ingredients, they can lead to higher or lower severities, or even different side effects altogether. A major reason to switch treatments may be side effects, so knowing which side effects to expect with Wegovy is important for making an informed decision.  The most commonly seen side effects of Wegovy pills are gastrointestinal in nature, meaning they occur within or originate from the digestive system; these include nausea, diarrhoea, vomiting, and constipation. Therefore, many effective ways to counter them are food-related, which brings us to:Managing Side Effects Through DietEating plain foods (toast, rice, crackers) and increasing your fluid intake (water, soup, peppermint tea) will help reduce what your stomach has to digest. Remember, Wegovy works in part by slowing down the speed of digestion, so consumables that pass through your stomach more easily will reduce nausea.Managing Side Effects Through LifestyleIn addition, physical and lifestyle changes are also effective ways to reduce side effects. After meals, try going for a light, slow walk to help with digestion. Or, simply sitting upright instead of lying down will allow the digestion process to occur more smoothly.If you find that after switching to Wegovy, your side effects are worse than they were on Mounjaro, speak to your clinician, as you may need to return to Mounjaro or try a different treatment altogether. Additionally, the full list of side effects can be read in the Wegovy pill Patient Information Leaflet. {add_product_block(476)} Frequently Asked Questions About Switching from Mounjaro to the Wegovy PillWe receive many questions about switching from Mounjaro to the Wegovy pill, which we see as a good thing. After all, you should be well-informed about which treatment is right for you. Here are some we are asked frequently:Can I Take Mounjaro and Wegovy Pills at the Same Time?No. You should wait 7 days before starting Wegovy pills after your last Mounjaro injection, and you should never take both at the same time. Since they both target the body in similar ways, the medications can interact with one another and lead to severe health issues or an overdose.When Should I Stay on Mounjaro?If your body is responding well to Mounjaro injections, you are seeing a steady rate of weight loss, and you are managing side effects well, your clinician may advise you to stick with it.It can be tempting to adopt a ‘grass is always greener’ outlook and believe that a different treatment may fast-track your weight loss progress, but you must keep in mind that the journey will be slow, no matter the medication you use. If Mounjaro is already helping, then it may be best to see it through and not disturb the momentum.Will my Dose Strength Reset After Switching?Not necessarily. Your clinician will conduct an assessment to decide which dosage amount to start you on. If you are early in your Mounjaro treatment, you may be started on the lowest Wegovy pill dose. It depends on many factors, and there is no universal answer, but rest assured, you will not be back to square one. The progress you have made so far is not going anywhere - provided you keep diet and exercise up.Can I Switch Back to Mounjaro?Yes, if you switched to the Wegovy pill and it isn’t working out, for whatever reason, you can switch back to Mounjaro injections. Your clinician will help you make this decision, and may even recommend trying a third, different treatment instead.If you decide to switch back to Mounjaro injections, since the medicine in a pill does not last as long in your system, you can often start Mounjaro a day or two after your last Wegovy pill. Once again, your clinician will guide you through the process, keeping you informed about exactly when you can resume your new (or old) medication.No Bait, All SwitchIf you believe that any of the reasons for switching mentioned in this article apply to your situation, one of our clinicians is available to listen. Our talented team will be able to advise and guide you through the process of switching from Mounjaro to the Wegovy pill, or, if you just want to talk through your options first, we can do that too. Prescription Doctor offers a wide range of weight loss treatments, so finding the one that fits you best is a streamlined, stress-free process with us.If you do make the switch, your new Wegovy pills will arrive in the post the exact same way all our treatments do - discreetly packaged and sent right to your door. We put a large focus on discretion and care to ensure you feel comfortable on your treatment, and we can even offer next-day delivery if your order is processed before 3pm on a weekday.The same level of security and care will be put into your order to ensure you feel comfortable with your new treatment.At the end of the day, your weight loss journey is your weight loss journey, and if it isn’t helping you to achieve the best results possible, then it’s our duty to support you in what you need. We’ve been helping people since 2013, and we’ve garnered a strong reputation for the quality and discretion of our service. Start your consultation today, and let’s hit your weight loss goal together. SourcesNHS (2026): Overweight and obesity in adults.NIH (2025): GLP-1-based therapies for diabetes, obesity and beyond.NEJM (2022): Tirzepatide Once Weekly for the Treatment of Obesity.NEJM (2025): Oral Semaglutide at a Dose of 25 mg in Adults with Overweight or Obesity.CoSRH (2025): GLP-1 Agonists and Contraception.NIH (2022): Efficacy and Safety of Tirzepatide in Adults With Type 2 Diabetes: A Perspective for Primary Care Providers.NEJM (2023): Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes.NHS (2025): GLP 1 Agonists (Mounjaro) and Contraception.NEJM (2025): Tirzepatide as Compared with Semaglutide for the Treatment of Obesity.EMC (2026): Wegovy Pill Patient Information Leaflet. 

Although weight loss tablets have been licensed for several years, none have acted on the glucagon-like peptide-1 (GLP-1) receptor to reduce food noise, suppress appetite, and increase feelings of fullness. That mechanism of action was limited to subcutaneous injections, such as Wegovy, until now.In 2026, Wegovy’s manufacturer, Novo Nordisk, secured approval for a GLP-1 tablet, commonly known as the Wegovy pill. This development is especially important for people who were considering a medicated weight loss programme, but were put off by the prospect of injecting themselves.But what exactly is the difference between the Wegovy pill vs injections, and which option may be better for your circumstances? Join us as we compare the two treatments, outlining key similarities and differences, dosage schedules, side effects, and more. Let’s begin.  [medical_form product_id="476" text="START YOUR CONSULTATION TODAY" type="button"] Is Wegovy a Pill or Injection?Wegovy is available as both a pill and an injection. As of June 2026, the UK Medicines and Healthcare products Regulatory Agency (MHRA) has licensed Wegovy for weight loss in both tablet and injectable forms. This development made the Wegovy pill the first glucagon-like peptide-1 (GLP-1) oral tablet approved for weight loss in the UK. Before this, Wegovy had only been approved and available as a weekly weight loss injection since its UK launch in 2023.Both the Wegovy pill and injections contain the same active ingredient, semaglutide, and are approved for adults living with obesity (a body mass index (BMI) of 30 or more) or those who are overweight (BMI between 27 and 30) with at least one weight-related health condition.The introduction of the Wegovy pill offers a new weight loss option for people who would prefer not to inject themselves while still benefiting from semaglutide.Similarities Between the Wegovy Pill and InjectionThe Wegovy pill and injection share several important similarities. Because they contain the same active ingredient and work in the same way to support weight loss, many of the benefits and risks associated with Wegovy remain consistent regardless of which type you use.The similarities between the Wegovy pill and injection are:They both contain semaglutide as their active ingredient.Both belong to a class of medications called glucagon-like peptide-1 (GLP-1) agonists.They are both licensed for weight loss and weight management.The Wegovy pill and injection reduce appetite while increasing feelings of fullness.For the best results, they are prescribed alongside a healthy diet and lifestyle changes.They are prescription-only medications.Both have similar side effect profiles, especially gastrointestinal effects such as nausea and constipation.Wegovy Tablet vs Injection: What is the Difference?Although they share similarities, there are distinct differences between the Wegovy pill and the injection. Some of these differences are why you may decide that one form is better suited to you and your lifestyle than the other. AdministrationThe biggest difference between the Wegovy pill and the injection is the way they are taken. The Wegovy pen is injected once weekly using a prefilled device. It can be administered with or without food, at any time of day, as long as the day you choose to inject remains consistent. {add_product_block(380)} Meanwhile, the Wegovy pill is a once-daily tablet that is swallowed whole on an empty stomach after at least 8 hours of fasting. Avoid splitting, crushing, or chewing it. When you have taken the pill, you will need to wait at least 30 minutes before eating, drinking, or taking any other oral medication to ensure semaglutide is effectively absorbed. It’s important to take the Wegovy tablet with no more than 120ml of still water, and not with any other beverage. AbsorptionBecause injectable Wegovy is injected into the body through the fatty tissue just below the skin’s surface, it is absorbed into the bloodstream more predictably. The tablet, however, must pass through the digestive system before being absorbed, which is why it has stricter administration instructions.ConvenienceThe Wegovy pill and injection both offer their own types of convenience. For example, some people will prefer the convenience of remembering to take their medication only once per week rather than daily, so they might choose the Wegovy pen. Others may prefer a daily pill because it avoids the use of needles and self-injection.In addition, the Wegovy pill also does not require special storage temperature instructions, which can make it a preferred option for people who travel frequently or do not have access to a fridge. The Wegovy injection has specific storage instructions depending on whether or not the pen is in use. DosesWhichever type of Wegovy you choose, you will always need to start on a low dose and titrate up gradually to help your body adjust to the medication and minimise the risk of side effects. However, there are different strengths of semaglutide available in the Wegovy pill vs injection, and the time between dosage increases is also slightly different. Is the Wegovy Pill as Effective as the Injection?Yes, current evidence suggests that the Wegovy pill can achieve weight loss results similar to the injectable version when taken as prescribed, although there are currently no direct studies comparing the Wegovy pill vs injections. The latest clinical trial, OASIS 4, has shown that oral semaglutide at a maximum daily dose of 25 mg can result in an average weight loss of 16.6% over 64 weeks.In comparison, the 2.4 mg Wegovy injection can support an average weight loss of 17.5%, while the maximum 7.2 mg has achieved an average weight loss of 20.7% over 72 weeks in the STEP UP trial. {add_product_block(476)} In practice, effectiveness often comes down to adherence. Some people find it easier to remember a weekly injection, while others are more comfortable taking a daily tablet. Missing doses, not following administration instructions, or stopping treatment early can reduce the effectiveness of either option.For most eligible patients, both formulations offer clinically meaningful weight loss when combined with healthy lifestyle changes.Wegovy Pill vs Injection Dosage ScheduleOne of the key differences between the Wegovy pill and injection is their dosage schedules. Although they both begin at a low starting dose and gradually increase until you reach a maintenance dose that is manageable and effective for you, the medication strength and titration duration differ.Wegovy Injection Dosage ScheduleWegovy injections are administered once weekly, and the dose is gradually increased over several months, typically every 4 weeks.The Wegovy injection dosage schedule is shown below:  Some people may choose to remain on a lower dose if their clinician agrees, perhaps because they are satisfied with the amount of weight they are losing or because they experience side effects on the higher doses.Wegovy Pill Dosage ScheduleThe Wegovy tablet is taken once daily and is gradually increased to improve tolerability. You will usually increase your dose every 30 days until you reach the maximum maintenance dose of 25 mg once daily. MonthDosage TypeDosage Strength1Starting Dose1.5 mg once daily2Continuation Dose4 mg once daily3Continuation Dose9 mg once daily4Maintenance Dose25 mg once daily If you experience side effects while taking the Wegovy pill, your clinician may discuss remaining on a lower dose longer or continuing at a dose you feel comfortable with, rather than reaching the maximum 25 mg dose.Wegovy Pill Side Effects Compared to InjectionsThe Wegovy pill and injection share very similar side effects because they contain the same active ingredient. The most common Wegovy injection side effects are gastrointestinal-related and include nausea, vomiting, diarrhoea, constipation, and abdominal pain.For most people, side effects are temporary and mild, and they improve as their bodies adjust to the medication. Gradual dose increases are designed to help minimise gastrointestinal side effects.One of the biggest differences is that Wegovy injection users may experience injection site reactions, including redness, bruising, itching, or discomfort where the medication is administered. Injection site reactions are not a side effect associated with the Wegovy pill. However, unlike the injection, the semaglutide tablet does list stomach upset and indigestion as a very common side effect that may affect more than 1 in 10 people.  If you get any side effects while taking the Wegovy pill or the injection that you find difficult to tolerate, you should speak to a doctor or pharmacist for advice. They may recommend trying a lower dose, staying on a lower dose longer, or switching to an alternative weight loss medication.Is the Wegovy Pill Cheaper Than Injections?There’s no significant difference between the cost of the Wegovy pill and injectable semaglutide. Both are similarly priced, giving you a real choice about how to proceed with your weight loss journey. Whether you choose semaglutide tablets or injections depends solely on what you believe will be most suitable for your circumstances and routine. Can I Switch from the Wegovy Injection to Pills?Yes, you will be able to switch from the Wegovy injection to the Wegovy pill if a clinician determines it is appropriate for you. The doses of the Wegovy pill and Wegovy injection are not biologically equivalent, so a clinician will advise you on the safest Wegovy pill to start your treatment with.The table below shows which Wegovy pill dose you can start with, depending on your current injection strength, following a consultation and approval from our clinicians: Current Injection DoseStarting Wegovy Pill Dose0.25 mg4 mg0.5 mg9 mg1 mg9 mg1.7 mg25 mg2.4 mg25 mg7.2 mg25 mg Switching from the Wegovy injection to oral semaglutide must be done under the supervision of a clinician. They will consider factors such as:Your current Wegovy doseHow well you're tolerating treatmentYour weight loss progressOther medications you're takingYour personal preferencesIf you are already using the Wegovy pen and are keen to switch to the Wegovy pill, our clinicians can help. {add_product_block(476)} Wegovy Pill or Injection: Which is Best For Me?Neither the Wegovy pill nor the injection is universally better. They both have pros and cons, and the best option will depend on your individual circumstances, preferences, and medical needs. Both the Wegovy pill and injection contain the same active ingredient and can support significant weight loss when combined with healthy lifestyle changes.Here are some of the reasons why you might choose the Wegovy tablet vs injection: CriteriaWegovy PillWegovy InjectionI dislike needles✓ I prefer taking tablets✓ I’d prefer a once-weekly treatment ✓I travel frequently✓ I find fasting requirements difficult to manage ✓I’m happy injecting myself ✓ People who would prefer a weight loss medication that does not require needles or self-injection may choose the tablet, whereas people who would prefer a once-weekly medication with few restrictions in terms of how to take it may favour the injection.A clinician can help you decide which treatment is most suitable for you based on your weight loss goals, preferences, and lifestyle. More information on the medications can be found within the Patient Information Leaflets for Wegovy pills and Wegovy injections. Could I Use the Wegovy Pill and Injection Together?No, you should not use the Wegovy pill and injection together because both formulations contain semaglutide. Taking them together will increase the amount of semaglutide in your system and raise the risk of side effects, including nausea, vomiting, dehydration, and other complications.The Wegovy pill and injection are intended to be alternative ways of taking the same medication and are not complementary treatments. Likewise, you must not take the Wegovy pill with any other weight loss medication, such as Mounjaro, or with weight loss pills such as orlistat (Xenical), alli, or Mysimba. A Tailored Approach to Weight LossNow that you understand the similarities and differences between the Wegovy pill vs injections, you may have a better idea of which medication might be most suitable for you. However, that’s not the only consideration you need to make, as you’ll also need to think about who you can trust to help you along your journey.Since 2013, we’ve been supporting people just like you and providing the guidance they need to reach their weight loss goals. We’re with you for the entire journey, from ensuring your chosen medication is suitable for your circumstances to regularly checking in to monitor your progress and how you’re coping with the treatment, and making suggestions or adjustments as needed. We recognise that everyone’s journey is different, so we tailor-make all aspects of our process to suit you.We also make the process of obtaining weight loss treatments as hassle-free as possible, giving you more control over your healthcare needs. You can complete our simple online medical questionnaire at any time, from the comfort of your own home, and our experienced team will take care of the rest. Our clinicians will assess your information to determine whether your chosen treatment is suitable for your circumstances before your order is passed to our General Pharmaceutical Council-registered pharmacy for dispatch. Orders approved before 3pm on a weekday are eligible for next-day delivery to your chosen address, so you can have swift, straightforward access to your treatment.Ready to get started? Ready to get started? Start a weight loss consultation with Prescription Doctor today and let us support you throughout your journey. 
 SourcesMHRA (2026): First GLP-1 tablet for weight loss approved in the UK. EMC (2026): Wegovy 9 mg tablets Patient Information Leaflet. NEJM (2025): Oral Semaglutide at a Dose of 25 mg in Adults with Overweight or Obesity. Bupa (2023): Obesity in adults. The Lancet (2025): Once-weekly semaglutide 7·2 mg in adults with obesity (STEP UP): a randomised, controlled, phase 3b trial.EMC (2026):  Wegovy 7.2 mg Solution for injection in pre-filled pen Patient Information Leaflet. 

If you’ve been researching medicated weight loss programmes, you've likely heard of Mounjaro. Containing the active ingredient tirzepatide, it has been clinically proven to help you lose weight when taken alongside positive lifestyle changes, such as a healthy diet and increased physical activity. Although it can be highly effective, the treatment involves self-administering an injection under the skin (subcutaneously) every week, something which may be an uncomfortable thought for some people.While weight loss tablets were an alternative, they didn’t offer the same potential results as Mounjaro or other injections, as they typically worked in different ways. This changed in June 2026, when the UK’s first GLP-1 pill for weight management was approved by the Medicines and Healthcare products Regulatory Agency (MHRA). Known as the Wegovy pill, this medication offers a real alternative if you have been put off by the idea of using injections.But how exactly does this tablet compare against tirzepatide (Mounjaro), and which option could be best for you? Join us as we compare the Wegovy pill vs Mounjaro, and cover key topics such as how the treatments work, the dosage schedule, potential results, and much more. Let’s begin.   [medical_form product_id="476" text="START YOUR CONSULTATION TODAY" type="button"] What are the Wegovy Pill and Mounjaro Injections?Both the Wegovy pill and Mounjaro injections are licensed weight loss treatments. The Wegovy pill is a daily oral medication containing semaglutide, while Mounjaro is a weekly injection containing tirzepatide. They are both suitable for adults with obesity or overweight-related health conditions, but they contain different active ingredients and are administered differently.The Wegovy pill is one of the latest weight loss treatments to be approved in the UK, receiving its license from the MHRA in June 2026. The Wegovy tablet contains the same active ingredient as injectable Wegovy, a glucagon-like peptide-1 receptor agonist. However, unlike the injections, the pills are taken orally once daily.Mounjaro, meanwhile, contains the active ingredient tirzepatide, which acts on two receptors, GLP-1 and GIP, so it is known as a dual GIP and GLP-1 receptor agonist. It is administered as a once-weekly injection using a prefilled pen.The treatments are intended to be used long-term alongside a reduced-calorie diet and increased physical activity to support significant weight loss. How Do Wegovy Pills and Mounjaro Work?Both Wegovy pills and Mounjaro help people lose weight by reducing appetite and helping them feel fuller for longer. However, Wegovy works by mimicking one hormone involved in appetite regulation, while Mounjaro targets two hormones, which may contribute to greater weight loss in some people.The Wegovy pill contains semaglutide, which mimics glucagon-like peptide-1 (GLP-1), a hormone naturally released after eating. This helps slow stomach emptying, reduce hunger signals, increase feelings of fullness, and lower calorie intake. Because semaglutide is a large peptide that is usually broken down in the stomach, researchers have had to develop a way to ensure it can travel through the digestive system without being destroyed by your stomach acid and digestive enzymes. The solution is a special coating called salcaprozate sodium, or SNAC for short. SNAC protects the active ingredient in the Wegovy pill from harsh digestive conditions by temporarily altering the stomach environment, allowing semaglutide to pass through the stomach lining and into the bloodstream.  Mounjaro contains tirzepatide, which activates both GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors. By targeting two metabolic pathways, Mounjaro may have a greater effect on appetite regulation and weight loss than GLP-1-only treatments. Because Mounjaro is injected, its active ingredient does not come into contact with the digestive system, so it is absorbed into the bloodstream and transported to the GLP-1 and GIP receptors in the brain. Both medicines also help improve blood sugar control, which can be particularly beneficial for people with type 2 diabetes or insulin resistance.How Do You Take the Treatments?How you take the Wegovy pill and Mounjaro is one of the key differences between the medicines. The Wegovy pill is taken once daily as a tablet, while Mounjaro is administered once weekly as an injection under the skin. The main reasons for choosing one over the other are convenience and personal preference.How To Take The Wegovy PillThere are several strict steps you must follow when taking the Wegovy pill to ensure it is effectively absorbed. When taking the Wegovy pill, you must:Take it on an empty stomach after a recommended 8 hours of fasting. Most people find that first thing in the morning is the easiest and most appropriate time to take it. You should take it around the same time every day.Swallow the pill whole with no more than 120 ml of water; no other drinks. You must also avoid chewing, crushing, or splitting the tablet.After taking the pill, you must wait at least 30 minutes before eating, drinking or taking any other oral medications. If you do not wait this time, the Wegovy pill may not be properly absorbed {add_product_block(476)} How To Take MounjaroMounjaro is a once-weekly injection that should be injected on the same day every week. It can be used at any time of the day, with or without meals. Mounjaro can be injected into your abdomen, thigh or upper arm. Read our guide for more detailed instructions about how to inject Mounjaro.For people who dislike needles, the Wegovy pill may offer a more appealing option. However, some people may find remembering a daily tablet less convenient than a once-weekly injection. {add_product_block(437)} Wegovy Pill vs Mounjaro Injection: Which is More Effective?Current evidence suggests that Mounjaro produces greater average weight loss results than the Wegovy pill. However, both treatments can be highly effective when combined with a healthy lifestyle, and individual results can vary depending on factors such as dosage, adherence, and overall health. For many people, choosing between Mounjaro and the Wegovy pill comes down to preference rather than effectiveness.The latest clinical trial involving oral semaglutide (Wegovy pill) is the OASIS 4 trial, which has shown that the highest available dose of 25 mg per day resulted in an average body weight loss of 16.6% over 64 weeks.Secondary analysis of the OASIS 4 trial revealed that, by week 64, people described as early responders achieved an average weight loss of 21.5%. These were individuals who lost 10% or more of their body weight by week 16.  These results are closer to Mounjaro's effectiveness, with an average weight loss of 22.5% at the maximum maintenance dose of 15 mg per week over 72 weeks. However, further studies have shown that after 88 weeks, the average weight loss with tirzepatide was 26%.That said, effectiveness is only one factor. Some people may achieve better long-term results with a treatment they find easier and more comfortable to use consistently.Wegovy Pill vs Mounjaro Dosage InformationBecause the Wegovy pill and Mounjaro injection contain different active ingredients, they are available in different strengths. However, they both use gradual dose increases to help minimise the risk of side effects and allow your body time to adjust to the medication, but these differ because one is a tablet and the other is a weekly injection.The Wegovy pill starts at a low dose and is gradually titrated every month (30 days) until you reach the maximum maintenance dose, typically within 4 months. The Wegovy pill dosage schedule is:  If you are already familiar with weight loss treatment doses, the maximum Wegovy pill dose may seem high, and there’s a reason for that. Because the Wegovy pill is an oral treatment which is vulnerable to the digestive process, its bioavailability is low. That is how much of the active ingredient is actually absorbed into the bloodstream and available to use. The bioavailability of the Wegovy tablet is only 1-2%.The Mounjaro dosing schedule is similar to the Wegovy pill, as it is gradually titrated over several months, with the dose typically increasing every 4 weeks. The Mounjaro dosage schedule is:  For some people, it may be advisable to remain on a lower dose for longer, especially if they experience side effects. So, whether you are taking the Wegovy pill or Mounjaro, a clinician will determine the most appropriate dose escalation schedule based on your individual response and tolerability. Wegovy Pill vs Mounjaro Injection Side EffectsThe Wegovy pill and Mounjaro share many side effects. For both, the most common adverse effects are gastrointestinal (GI)-related, such as nausea, vomiting, diarrhoea, and constipation. For most people, Wegovy pill or Mounjaro side effects are most prominent when they first begin treatment and at every dose increase, but they are usually mild and improve as your body gets used to the medication.In the OASIS 4 trial, 74% of people reported at least one GI side effect, while in the SURMOUNT-1 trial, gastrointestinal effects were the most commonly reported among people receiving tirzepatide, with up to 82% experiencing at least one Mounjaro side effect. Wegovy Pill vs Mounjaro Side Effects ComparedThe table below compares some of the potential side effects of the Wegovy pill and Mounjaro.FrequencyWegovy PillMounjaroVery common (may affect more than 1 in 10 people)
 Headache
Feeling sick (nausea)
Being sick (vomiting)
Diarrhoea
Constipation
Stomach pain
Feeling weak or tired
Upset stomach or indigestion
Dizziness
Burping 
Gas (flatulence)
Bloating
Inflamed stomach (gastritis)Low blood sugar when Mounjaro is used to treat type 2 diabetes
Feeling sick (nausea)
Diarrhoea
Being sick (vomiting)
Stomach pain
ConstipationCommon (may affect up to 1 in 10 people
 Dizziness
Burping 
Gas (flatulence)
Bloating
Inflamed stomach (gastritis)Low blood sugar when Mounjaro is used in adults with type 2 diabetes with metformin and a sodium-glucose co-transporter 2 inhibitor
Allergic reaction
Dizziness
Low blood pressure
Reduced appetite
Indigestion
Bloating
Burping
Gas (flatulence)
Reflux or heartburn
Hair lossUncommon (may affect up to 1 in 100 people)
 Inflamed pancreas
Kidney or bladder stonesLow blood sugar when Mounjaro is used with metformin in people with type 2 diabetes
Weight loss in type 2 diabetes patients
Injection site pain
Gallbladder infection (cholecystitis)
Taste changes
Changes in skin sensations
Delayed stomach emptyingRare (may affect up to 1 in 1,000 people)
 Severe allergic reactions
Hip fracturesSevere allergic reactions Please note that the above is not an exhaustive list of possible side effects of the Wegovy pill and Mounjaro. More information can be found in the Wegovy tablets Patient Information Leaflet and the Mounjaro Patient Information Leaflet, respectively. One of the key differences between the Wegovy pill and Mounjaro injections, when considering side effects, is that the Wegovy pill does not cause injection site reactions.If you experience any Wegovy pill or Mounjaro side effects that concern you or are difficult to manage, speak with your doctor. They may suggest lowering your dose, remaining on a lower dose longer, or considering an alternative weight loss treatment.Is the Wegovy Pill Cheaper than Mounjaro?Yes, the Wegovy pill is cheaper than Mounjaro and comparable in cost to Wegovy injections. This gives you more control over your weight-loss journey, as you’ll be able to choose the treatment that best fits your lifestyle and schedule.The tablet below outlines the price of oral Wegovy at Prescription Doctor:
 DosagePrice1.5 mg£1154 mg£1209 mg£13525 mg£180 Meanwhile, this table covers the price of Mounjaro injections at Prescription Doctor: DosePrice2.5 mg£169.995 mg£199.997.5 mg£249.9910 mg£279.9912.5 mg£289.9915 mg£298.88 It’s important to note that cost should not be the only factor in determining which medication you choose. Careful consideration of various elements, such as the dosage schedule, side-effect profile, and treatment regimen. If you’re ever unsure about which may be best for you, our clinicians are here to help. Can I Switch from Mounjaro to the Wegovy Pill?Yes, it is possible to switch from Mounjaro to the Wegovy pill, as long as the switch is made under a clinician's guidance. You must not switch on your own. Because Mounjaro and Wegovy contain different active ingredients and work in slightly different ways to support weight loss, there is no direct dose conversion.The table below gives you an idea of what your starting dose of the Wegovy pill could be with Prescription Doctor. Please note that our clinicians will review each individual's circumstances on a case-by-case basis, so your actual starting dose of Wegovy pills may be different.  Current Mounjaro DoseStarting Wegovy Pill Dose2.5 mg4 mg5 mg4 mg7.5 mg9 mg10 mg9 mg12.5mg9 mg15 mg25 mg When you switch from Mounjaro to the Wegovy pill, there will be a 7-day washout period. This means that you must wait 7 days between your final Mounjaro dose and your first Wegovy pill to avoid overlapping side effects.If you are thinking about switching from Mounjaro to the Wegovy pill, our clinician can help. You’ll need to have a short online consultation that includes a medical questionnaire so our clinicians can ensure switching is possible for you and that the Wegovy pill is a safe treatment for you. {add_product_block(476)} Where Can I Buy the Treatments?Both Mounjaro and the Wegovy pill can be purchased via a private prescription from a reputable pharmacy like Prescription Doctor. A consultation is required to determine whether the treatments are suitable for your circumstances. Mounjaro is also available on the NHS; however, this approach is subject to much stricter criteria and may involve a long waiting list. Wegovy Tablets vs Mounjaro: Which is Best?Because everyone’s weight loss journey is different, exactly which of the two treatments will benefit you most depends on your personal circumstances. You may not like the idea of injecting yourself and would feel more comfortable taking a tablet. On the other hand, the fasting requirements for the Wegovy pill may not fit around your schedule. It is entirely up to you and what you feel you can work with.Other variables include how your body interacts with the medication and whether you can tolerate the potential side effects. You may even be taking other treatments that could interact with Mounjaro or the Wegovy pill. Potential results could even be a factor, with tirzepatide offering a slightly higher average weight loss than Wegovy tablets. A lot of thought is required to determine which option you should choose.If you’re ever unsure, it’s recommended to speak to an experienced clinician who can help you consider what you want from your weight loss programme and your preferences. This will enable you to make a more informed and well-rounded decision. With You For The Journey Starting a medicated weight loss programme is an important decision. It takes hard work and dedication to achieve success, as you will need to commit to making more positive lifestyle choices. The good news is that you won’t have to go through it alone, as Prescription Doctor is here to help.Since 2013, we have cultivated a strong reputation for the quality of our service and support. We have helped countless individuals just like you to achieve their goals, thanks to an approach that places your requirements at the forefront of everything we do.Our process begins with a brief online questionnaire to understand your medical history and any other treatments you may be taking. This is then reviewed by our experienced clinicians to determine whether your chosen medication is suitable for your circumstances or if an alternative may be better. Approved orders are then dispatched by our General Pharmaceutical Council-registered pharmacy in plain packaging to your chosen UK address.The service doesn’t just stop there, either, as our clinicians will regularly check in with you to monitor progress and ensure everything is working as it should. You can also get in touch at any time if you have any queries about your treatment programme. We are here to help you succeed.Think you’re ready to take the first step? Start a consultation with Prescription Doctor today and let us guide you through your weight loss journey.  SourcesEMC (2026): Mounjaro KwikPen 2.5mg solution for injection in pre-filled pen.EMC (2026): Wegovy 25 mg tablets.MHRA (2026): First GLP-1 tablet for weight loss approved in the UK. NEJM (2025): Oral Semaglutide at a Dose of 25 mg in Adults with Overweight or Obesity. NEJM (2022): Tirzepatide Once Weekly for the Treatment of Obesity.Novo Nordisk (2026): Early Responders to Oral Semaglutide 25 mg: A Post Hoc Analysis of the OASIS 4 Trial.University of Glasgow (2024): Continued treatment with Tirzepatide for maintenance of weight reduction in adults with obesity: The SURMOUNT-4 randomised clinical trial.EMC (2026): Mounjaro Patient Information Leaflet.EMC (2026): Wegovy tablets Patient Information Leaflet. 

A medicated weight loss plan can be a useful tool for reaching your goals, provided it is used alongside a healthy diet and positive lifestyle choices. While there are no quick fixes, GLP-1 medications such as Wegovy and Mounjaro could lead to average weight reductions of 20.7% and 22.5%, respectively.One potential downside of these treatments, however, is that they are usually self-administered subcutaneous (under the skin) injections. This may make them unsuitable for people who have a phobia of needles or are put off by the thought of injecting themselves. This landscape changed in June 2026, when UK regulators approved an oral Wegovy tablet for weight loss.Now it’s available, this new Wegovy oral tablet could be a positive alternative to the injections and make weight loss more achievable for some people. But what exactly is the Wegovy pill, how does it work, and how effective is it? Join us as we explain it all.  [medical_form product_id="476" text="START YOUR CONSULTATION TODAY" type="button"] What is the Wegovy Tablet?The Wegovy pill is a once-daily weight loss medication that was approved by the Medicines and Healthcare products Regulatory Agency (MHRA) on 11 June 2026 for obese or overweight adults with weight-related health conditions. The Wegovy tablet is the first glucagon-like peptide-1 receptor agonist pill approved in the UK specifically for weight management.The tablet contains semaglutide, the same active ingredient found in Wegovy injections. However, instead of being taken once weekly, the Wegovy pill is taken orally once a day.The approval of the Wegovy tablet means the UK is the first country in Europe to approve the treatment and only the third country in the world to license it for weight loss. In announcing the approval, Julian Beach, Executive Director of Healthcare Quality and Access at the MHRA, stated:“Having met the MHRA’s rigorous standards of safety, quality and effectiveness, the semaglutide tablet has been approved in the UK for weight loss and weight management.”The oral Wegovy pill will be available in a range of doses, starting at 1.5 mg and gradually increasing to a maximum maintenance dose of 25 mg per day.  How Does the Wegovy Oral Tablet Work?The Wegovy tablet works by mimicking glucagon-like peptide-1 (GLP-1), a naturally produced hormone that regulates appetite, food intake, and blood sugar levels. By acting on the brain regions that control your appetite, oral semaglutide helps reduce hunger, increase fullness, and support long-term weight loss.For it to be effective, you will need to make lifestyle changes while taking Wegovy. So, you’ll need to follow a calorie-controlled diet and increase physical activity.Because semaglutide is a peptide medicine that would normally be broken down in the stomach, the tablet has a special absorption-enhancing ingredient called salcaprozate sodium (SNAC). This is designed to protect the medicine from stomach acid, so it has enough time to be absorbed into the bloodstream.There are also some very strict instructions you must follow when you take the oral Wegovy pill. You must:Take the tablet on an empty stomach, after fasting for a recommended 8 hours. Most people find the best time to take the Wegovy tablet is first thing in the morning as soon as they wake up.Only take the Wegovy pill with up to 120 ml of plain water. No other drink, including tea, coffee, or juice, is suitable, as it can affect absorption.Wait at least 30 minutes after taking the oral Wegovy pill before eating, drinking, or taking any other oral medication.If you do not follow these instructions carefully, the Wegovy tablet may be ineffective because it may not be absorbed into the bloodstream.How Effective is the New Wegovy Tablet?The OASIS 4 clinical trial shows that the maximum 25 mg dose can help you lose between 13.6% and 16.6% of your starting body weight after 64 weeks. In the trial, the average weight loss amongst all participants, regardless of whether they reduced their dose, had side effects, or dropped out of the trial, was 13.6%. However, when only those who fully adhered to and completed the trial are considered, the average weight loss was 16.6% over 64 weeks.  In the trial, people given the Wegovy tablet were significantly more likely to lose at least 5%, 10%, 15%, or 20% of their body weight than those given a placebo, making it an effective oral weight loss treatment. A secondary analysis of the OASIS 4 trial found that 28.8% of people on the 25 mg Wegovy pill were considered early responders, achieving at least 10% body weight loss by week 16. These individuals subsequently lost an average of 21.6% by week 64. In addition, people who lost at least 7.5% of their starting weight by week 16 went on to lose an average of 20.3% by week 64. The trial also found that oral semaglutide results in faster weight loss than placebo, with the average time to achieve at least 5% weight loss being 12 weeks, compared to 40 weeks with placebo.  Where Can I Buy Wegovy Tablets in the UK?Wegovy tablets will be available privately with a prescription from UK-registered pharmacies, such as Prescription Doctor, and from clinics following a consultation with a clinician. It cannot be acquired without a prescription from a healthcare professional and will not yet be available on the NHS as it has not been approved by the National Institute for Health and Care Excellence (NICE).The Wegovy tablet will be available for adults who have a body mass index (BMI) of:30 kg/m² or above, or27 kg/m² or above and at least one weight-related medical condition such as type 2 diabetes, obstructive sleep apnoea, or high blood pressureYou must purchase weight loss medication only from regulated UK pharmacies registered with the General Pharmaceutical Council (GPhC).When Will the Wegovy Pill Be Available in the UK?The Wegovy Pill is now available from reputable pharmacies, including Prescription Doctor. We’re here to support your weight loss journey every step of the way, from determining whether the medication is suitable for your circumstances to providing essential information as needed. We’ll even check in with you to monitor progress and ensure everything is going to plan.  {add_product_block(476)} Will the Wegovy Tablet Be Available on the NHS?No, the Wegovy tablet will not be available on the NHS yet. Although it has received MHRA approval, the Wegovy tablet must undergo NICE approval before routine NHS funding can be considered.The process evaluates whether a medication offers sufficient clinical benefit and value for money for use in the NHS. Until it is approved by NICE, people who wish to access the Wegovy tablet will need to do so via a private prescription.Even if the Wegovy pill becomes available on the NHS, it is likely to be limited to people who first meet specific NHS eligibility criteria, similar to the Wegovy injection pen. How Much Will the Wegovy (Semaglutide) Pill Cost?Prescription Doctor is pleased to offer the Wegovy pill at the following prices: DosagePrice1.5 mg£1154 mg£1209 mg£13525 mg£180 This means the Wegovy pill is priced comparably to semaglutide injections, giving you more control over your weight-loss journey. This is because you have a real choice between the two options, based solely on your schedule and preferences. Is There a Difference Between the Wegovy Pill and Wegovy Injections?Yes, although the Wegovy tablet and Wegovy injection both contain semaglutide as their active ingredient and work in the same way, there are differences in how they are administered, dosing schedules, and how often you need to take them. One thing that remains the same is that they both require you to make healthy lifestyle changes to be effective.  CharacteristicWegovy PillWegovy InjectionActive ingredientSemaglutideSemaglutideMethod of administrationOral tabletSubcutaneous injectionFrequencyOnce dailyOnce weeklyStarting dose1.5 mg0.25 mgMaintenance dose25 mg daily1.7, 2.4, or 7.2 mg weeklyStorageNo special storage temperature instructionsRefrigerate before 1st use, then keep refrigerated or at room temperatureNeedle required?NoYesPrescription only?YesYes The main differences between Wegovy pills and Wegovy injections are:AdministrationThe most obvious difference between the Wegovy tablet and the injection is the route of administration. Wegovy tablets are swallowed whole, once daily with no more than 120 ml of water, while Wegovy injections are administered under the skin using a pre-filled injection once per week. For people who do not like needles or feel uncomfortable self-injecting, the tablet may offer a more convenient alternative.Dosing ScheduleThe dosing schedules for the Wegovy pill and injection are different. However, they both start on a low dose to help your body adapt to the new medication and reduce the risk of side effects.The Wegovy injection has a starting dose of 0.25 mg once weekly, which is titrated every 4 weeks until you reach a maintenance dose that is most suitable for you. The dosing schedule for the Wegovy pen is as follows:  The Wegovy pill, on the other hand, has a starting dose of 1.5 mg per day, which increases every month (30 days) until you reach the maximum maintenance dose of 25 mg per day.  Administration RequirementsThe oral Wegovy pill comes with stricter administration instructions than the injections. It must be taken on an empty stomach with no more than 120 ml of water, and you must wait at least 30 minutes before eating, drinking, or taking any other medications. Wegovy injections have fewer restrictions and can be administered at any time of the day with or without food, as long as they are taken on the same day each week.Side EffectsThe most common side effects of the Wegovy injection and tablet are similar. They are:HeadacheFeeling sick (nausea)Being sick (vomiting)DiarrhoeaConstipationStomach painFeeling weak or tiredThe Wegovy pill can also cause an upset stomach or indigestion. Most people experience these side effects when they first start treatment or after each dose increase. They are often mild and improve as your body gets used to semaglutide. However, if you experience any side effects that are difficult to manage or worsen, contact your doctor for advice.  Storage and TravelThe Wegovy tablet has no special storage temperature requirements, making it particularly convenient for travel. Wegovy injection pens have specific storage instructions. They require refrigeration before first use, although they can be stored at room temperature for a limited period once in use. For frequent travellers, the tablet may be the more practical option.Which Option Is Right for You?Both the Wegovy tablet and Wegovy injections are effective for weight loss when combined with a healthy diet and regular physical activity. Patients who prefer a needle-free option may favour the tablet, while those looking for the convenience of once-weekly dosing may prefer injections. A clinician can help determine which treatment is most suitable based on your medical history, lifestyle, and weight loss goals.A more detailed comparison between Wegovy pills and injections is available on our website. Is the Wegovy Tablet as Effective as Wegovy Injections?Current evidence from clinical trials suggests that the Wegovy tablet can deliver significant weight loss results comparable to those of Wegovy injections when taken correctly and consistently. However, there has not been a trial that directly compares the effectiveness of the Wegovy pill and the Wegovy injection.The OASIS 4 trial, which investigated the effectiveness of a 25 mg oral Wegovy pill, found that after 64 weeks, the average weight loss ranged from 14% to 17%. In the STEP UP trial, the maximum maintenance Wegovy injection dose of 7.2 mg resulted in an average weight loss of 20.7%. {add_product_block(476)} How much weight you will lose on Wegovy depends on several factors, such as adherence, lifestyle, and dosage. The tablet requires a higher dose because some of the medication is lost during digestion, whereas injectable semaglutide enters the bloodstream directly. Despite this difference, clinical trials have shown very similar overall weight loss outcomes.For many patients, the decision may come down to personal preference rather than effectiveness.Can I Switch to the Wegovy Oral Tablet From My Existing Treatment?Yes, it may be possible to switch from an existing injectable weight loss medication, such as Wegovy or Mounjaro, to the Wegovy oral tablet, provided the switch is approved by a clinician. They will also determine your starting dose of Wegovy tablets, depending on the strength of your current treatment and how you are responding to the medication. Moving from Wegovy Injections to TabletsThe doses of the Wegovy pill and injection are not biologically equivalent, so a clinician will tell you which is the safest Wegovy tablet dose to begin your treatment on.The table below outlines our policy when it comes to what your starting dose of the new Wegovy pills could be: Current Injection DoseStarting Tablets Dose0.25 mg4 mg0.5 mg4 mg1 mg4 mg or 9 mg depending on side effects1.7 mg9 mg2.4 mg25 mg7.2 mg25 mg Your clinician will advise you on the best way to switch to the Wegovy tablet to ensure everything is safe and suitable for your circumstances.Moving from Mounjaro Injections to Wegovy TabletsIf you’re currently using Mounjaro injections, it may be suitable for you to switch to the Wegovy pill if you wish to do so. Our clinicians will review your progress and how you are dealing with tirzepatide side effects to determine if making the switch is safe for your circumstances. If you'd like more information, please see our comparison article between Mounjaro and Wegovy pills. The table below provides an idea of what your starting dose of oral semaglutide could be if you decide to change from Mounjaro to Wegovy tablets.  Current Mounjaro DoseStarting Wegovy Pill Dose2.5 mg4 mg5 mg9 mg7.5 mg9 mg10 mg9 mg12.5 mg25 mg15 mg  Please note that there will be a 7-day washout period before you start your new treatment regimen. This means that you must wait 7 days between your last Mounjaro injection and first Wegovy pill, to avoid the potential of overlapping side effects. A Weight Loss Programme Centred Around YouOne of the most important things to remember when considering a medicated weight loss programme is that everyone’s journey is different. While clinical trials can imply a certain level of progress, some individuals may take a bit longer to achieve similar results, while others may have different goals altogether. The crucial thing is that you do it your own way.Prescription Doctor is here to help with this. We’re with you every step of the way, from assessing whether your chosen medication is suitable for your circumstances to regularly checking in with you to ensure your journey is progressing well. You can also seek advice from our experienced clinicians any time you have a query about your treatment schedule.We’ve made it our mission to simplify access to healthcare, which is why you can start a consultation online at any time from your own home. There’s no need to make an appointment. Once your order is approved, our General Pharmaceutical Council-registered pharmacy will dispense your medication in plain, discreet packaging. Anything approved before 3pm on a weekday is also eligible for next-day delivery to your chosen address; it’s that straightforward. It’s therefore no surprise that we’ve cultivated a strong reputation for the quality of our service.Ready to make the first move? Start a weight loss consultation with Prescription Doctor today. 
 SourcesEMC (2026): Wegovy 0.25 mg, FlexTouch solution for injection in a pre-filled pen.MHRA (2026): First GLP-1 tablet for weight loss approved in the UK. EMC (2026): Wegovy 9 mg tablets Patient Information Leaflet. NEJM (2025): Oral Semaglutide at a Dose of 25 mg in Adults with Overweight or Obesity. Novo Nordisk (2026): Early responders to oral semaglutide 25 mg: A post hoc analysis of the OASIS 4 trial.The Lancet Diabetes & Endocrinology (2025): Once-weekly semaglutide 7·2 mg in adults with obesity (STEP UP): a randomised, controlled, phase 3b trial.NEJM (2022): Tirzepatide Once Weekly for the Treatment of Obesity.