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About Product
Mohamed Imran Lakhi
This content has been written and checked for quality and accuracy by
Mohamed Imran Lakhi Content Administrator Updated on: 27/01/2022 Next review: 27/07/2022

What is Lymecycline used for

Lymecycline is a type of oral antibiotic. It is prescribed for the treatment of acne.

Lymecycline is a long-acting acne treatment belonging to the tetracycline class of antibiotics.

Lymecycline stops the growth of bacteria that causes acne.

According to Nice, it is recommended to use a topical retinoid or benzoyl peroxide when taking an oral antibiotic to treat acne.

With Prescription Doctor, we offer a combination pack of Epiduo gel and Lymecycline capsules to treat severe acne. You will have the option to select this variation pack after the consultation.

How does Lymecycline treat acne?

Lymecycline treats acne by killing bacteria that are responsible for acne.

When a pore becomes clogged, sebum builds up beneath the skin's surface.

Bacteria feed on sebum and excrete chemicals that cause skin irritation and inflammation.

By killing the bacteria, the skin has a chance to heal.

How long does Lymecycline take to work?

When treating acne with Lymecycline, it may take up to 8 weeks for the effects of the treatment to become noticeable.

You may notice a difference within the first week of taking Lymecycline; however, this may be different for each person.

It is essential to complete the course of antibiotics, even if the symptoms subside or you feel better. Stopping the treatment of antibiotics can cause the bacterial infection to return or may affect how your body responds to future antibiotic treatments.

If you do not notice an improvement in your condition after eight weeks, speak to your doctor. They may change your dosage or offer an alternative treatment entirely.

Lymecycline dosing

Tetralysal and generic Lymecycline are available in 408mg capsules.

  • Take one capsule daily.
  • Swallow Lymecycline capsules whole with a glass of water.
  • Lymecycline can be taken with or without food.

It would help if you took Lymecycline at the same time each day, though it is recommended to take them in the morning.

What should I do if I forget to take a dose of Lymecycline?

  • If you miss a dose of Lymecycline, take it as soon as you remember.
  • If you often forget when to take Lymecycline, set a reminder on your phone or smart device.

Do not take more of the medicine to make up for missed doses.

What should I do if I accidentally take too much?

If you accidentally take too much Lymecycline, speak to your doctor or pharmacist as soon as possible.

Lymecycline side effects and cautions

All medications carry the risk of side effects; however, not everyone experiences these side effects.

Common Lymecycline side effects include:

  • Nausea and vomiting
  • Stomach ache
  • Diarrhoea
  • Headaches

Who should not take Lymecycline?

Do not take Lymecycline if you:

  • are under 12 years old
  • ever had kidney disease
  • are pregnant or breastfeeding
  • are allergic to or any of the ingredients

To learn more regarding the side effects of Lymecycline, visit the NHS website.


If you experience the signs of an allergic reaction, stop taking medicine and seek emergency medical attention by going straight to your nearest accident and emergency department. Remember to take the packaging and any remaining medicine with you so that the doctors know what you have taken.

Signs of an allergic reaction include:

  • Chest tightening
  • Dry, red and cracked skin
  • Itchy, red, watery eyes
  • Raised, itchy, red rash (hives)
  • Swelling of the lips, tongue, eyes or face
  • Tummy pain, nausea, vomiting or diarrhoea
  • Wheezing

How does Lymecycline interact with other medicine? 

Lymecycline or Tetralysal can interact with certain medicines. These include:

  • medications used to thin your blood (e.g. warfarin)
  • diuretics (used to treat kidney disease, heart disease or high blood pressure)
  • It can also interact with other acne antibiotic medicines.

If any of the above interactions apply to you, please notify us immediately.

Do not take any of the following medicines at the same time as Lymecycline:

  • antacids and other indigestion treatments
  • drugs to treat ulcers
  • quinapril (for high blood pressure)
  • supplements containing calcium, aluminium, magnesium, zinc or iron

Pregnancy and breastfeeding

Do not take Lymecycline or Tetralysal if you are pregnant or think you might be pregnant. 

If you are pregnant, speak to your doctor about alternative treatments which are safer for you and your baby.

If you become pregnant during your course of treatment, inform your doctor straight away. They will discuss alternative treatments for acne with you.

Frequently asked questions

Can I drink alcohol while taking Lymecycline?

Yes, it is safe to drink alcohol in moderation while taking Lymecycline. Avoid drinking more than 14 units of alcohol per week. Consuming high quantities of alcohol may increase your risk of side effects such as dizziness and nausea.

Can I get Lymecycline over the counter?

No, Lymecycline is only available on prescription and cannot be bought over the counter. With Prescription Doctor, you can get a private prescription for Lymecycline online following an online consultation with one of our doctors. If our doctor deems the treatment suitable for you, they can issue a prescription for Lymecycline, which our UK based pharmacy can fulfil.

Is Lymecycline the same as Tetralysal?

Tetralysal is a brand name treatment for acne, which contains 408 mg of Lymecycline.

Both medicines contain the same active ingredient; Lymecycline.

Does Lymecycline (Tetralysal) cause weight gain?

Weight gain has not been reported as a side effect of Lymecycline or Tetralysal. If you notice any significant change in your weight, inform your doctor as soon as possible.

How much does Lymecycline cost?

At Prescription Doctor, we offer 28 capsules for £19.99. Our prices can be reviewed at the top of the page by clicking on "Review more prices".

Will Lymecycline affect my contraceptive or birth control pills?

Lymecycline is not known to interact with hormonal contraceptives, including the combined contraceptive pill or the morning-after pill.

If you experience vomiting or diarrhoea for 24 hours after taking your contraceptive pill, as a side effect of Lymecycline, the contraceptive effect may be reduced.

Further information on what to do in this situation can be found within the patient information leaflet for your contraceptive pill. You can also seek advice from your doctor or a pharmacist if you are unsure.

Does Lymecycline affect fertility?

Lymecycline does not impact fertility in men or women. If you have any concerns about your fertility, speak to your doctor or a pharmacist before taking Lymecycline.

Does Lymecycline cause thrush?

Antibiotics, such as Lymecycline, can cause thrush in some people who take them.

If you experience the symptoms of oral or vaginal thrush during your course of Lymecycline, speak to your doctor or ask a pharmacist for advice.

Does Lymecycline stain teeth?

Lymecycline may stain developing teeth. For this reason, it is not recommended for children under 12 years old or women who are pregnant or breastfeeding.

If you are concerned about side effects associated with Lymecycline, speak to your doctor or a pharmacist.

Additional resources

10 foods to avoid if you want clear skin

How to use tea tree oil for acne

What causes 'bacne', and how is it treated?

Natural ways to control your acne

Control your hormones; control your acne


NHS, 2018. Lymecycline.

British Association of Dermatologists (BAD), 2020. Acne.

NHS, 2019. Acne: Overview, causes, diagnosis, treatment, complications.

Galderma, 2020. Tetralysal 300mg Hard Capsules: Summary of Product Characteristics

Treatment information

  • Product Name: Lymecycline
  • Active Ingredient(s): Lymecycline
  • Presentation: Capsules
  • Available Quantity: 408 mg
  • Exemption: Prescription Only Medicine
  • Application: Men and women over 18 with acne
  • Dosage: Take one tablet per day
  • Description: Antibiotic treatment for acne
  • Drug Class: Antibiotic
  • Alcohol Consumption: Avoid excessive alcohol consumption
  • When Pregnant: Tell our prescriber if you are pregnant or intend on becoming pregnant
  • When Breastfeeding: Tell our prescriber if you are breastfeeding

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