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Epiduo is a topical acne treatment which contains a retinoid called adapalene and a keratolytic agent called benzoyl peroxide.
The treatment is available as an off-white opaque gel which is applied directly to the affected area. Epiduo only needs to be applied to the skin once a day, unlike other acne treatments which may need to be used a few times every day.
You can buy Epiduo gel in 45g, 90g and 135g tubes from Prescription Doctor's trusted online pharmacy. To begin your order, simply complete our short online consultation for one of our doctors to review. If your order is approved before 3pm, they will issue a prescription for Epiduo which our UK based pharmacy will process.
Our pharmacy will package your item in discreet packaging which does not reveal its content. Orders are sent via a next-day tracked delivery service, so that you can get your treatment as soon as tomorrow.
Our doctors are available online to answer any questions you may have about your condition or the treatment itself.
To get started, click here.
Acne is a skin condition which causes spots on the skin, especially around the face. It commonly affects teenagers during puberty, although some adults do experience breakouts of acne.
There are a number of different factors which can trigger the development of acne spots. Some of these factors may be easier to manage than others. It's important to speak to your doctor to determine the cause of your acne and seek the most suitable treatment for you.
Some common causes of acne include hormonal changes, genetics, pregnancy, menopause, smoking and medications.
If you suspect a medication you are taking may be the cause of your acne, speak to your doctor. You shouldn't stop taking a medication that has been prescribed to you without first consulting your doctor.
Acne starts when a pore in the skin becomes blocked with dead skin cells and keratin, a substance which hairs and nails are made from.
Sebaceous glands below the surface of the skin secrete an oily substance called sebum. Sebum forms a protective layer over the skin and keeps the skin (epidermis) hydrated.
With the pore blocked, the sebum has no way to escape so it builds up under the skin.
Bacteria begin to feed on this excess build-up of sebum. When the bacterium feed, they excrete fatty acids and other materials which irritate the sebaceous glands and surrounding tissues, resulting in inflammation.
The body's immune system may respond to this and fight the bacteria. During this period, dead cells and bacteria accumulate in the head of the acne spot, creating pus.
While the body is good at clearing the odd blemish or a single spot, acne break outs are much harder for the body to control and may require treatment to get rid of them.
Epiduo combines both a retinoid and a peeling agent which work together to clear acne.
The retinoid (adapalene) unblocks the pores of the skin to prevent acne from forming under the skin, while also reducing redness and inflammation of the affected area.
Benzoyl peroxide (keratolytic peeling agent) has antimicrobial properties which kills bacteria under the acne spots. It also helps to remove dead skin cells, keratin and sebum from the skin.
When used consistently, Epiduo is an effective treatment for acne which is suitable for people who have tried adapalene and benzoyl peroxide agents on their own but have not had good results.
Epiduo is applied topically to the affected areas once a day, typically at night before bed.
Use the treatment regularly at the same time each day for the best results. Using more treatment than prescribed will not improve your acne any faster.
Before you apply Epiduo, wash the affected areas of the skin with warm water and a mild soap. Pat the area dry before applying the treatment.
Using only a pea-sized amount, apply a thin layer of Epiduo gel to the affected areas of the skin once a day.
Always wash your hands after applying the treatment.
If you accidentally apply too much of the gel, simply wipe away the excess with a clean tissue and discard it safely.
Please understand that using more Epiduo than prescribed by your doctor will not clear your acne faster, but it may increase your risk of experiencing side effects.
Do not apply Epiduo to broken skin.
Take care when applying Epiduo to areas around the eyes, nose and mouth. If you get some Epiduo in your eyes, rinse your eyes with water. If you experience irritation long after rinsing it, contact your doctor immediately.
Epiduo comes in a tube with a screw-on top. To get the most out of your Epiduo gel, roll the tube from the bottom rather than squeezing it from the side. This will prevent the gel getting trapped in creases as you use Epiduo.
If you are unsure about how to apply Epiduo, or how much you should use, ask a doctor or pharmacist for advice.
All medications carry the risk of side effects, though not everybody experiences them. It's important to educate yourself on the side effects which could be caused by your medication in order to stay safe.
Information regarding the safety of Epiduo can be found within the patient information leaflet enclosed with your medicine. Alternatively, you can view the leaflet online here.
During the first week of treatment, your risk of side effects is greatest as your skin adjusts to the medication.
Before taking your first dose, you may wish to perform a patch test. Clean an area of your skin with warm soapy water and pat dry. Apply a very small amount to the area of clear skin and leave for 24 hours. If you experience an allergic reaction, consult your doctor immediately.
Common side effects (may affect up to 1 in 10 people) of using Epiduo include:
Uncommon side effects (may affect up to 1 in 100 people) of using Epiduo include:
This is not an exhaustive list of side effects. Further information regarding the safety of Epiduo, including a complete list of side effects can be found within the patient information leaflet enclosed with your medication.
If you experience any side effects, regardless of whether they are listed above or in the patient information leaflet, report them to your doctor, ask a pharmacist or dial NHS 111 for advice.
Do not use Epiduo if you are allergic to adapalene, benzoyl peroxide or any of the other ingredients listed in the patient information leaflet.
If you experience the signs and symptoms of an allergic reaction, stop using Epiduo and inform your doctor right away. For severe allergic reactions such as suspected anaphylaxis, go straight to your nearest accident and emergency department. Remember to take the packaging and any remaining medication with you so that the doctors know exactly what you have taken.
Signs of an allergic reaction include:
Do not use Epiduo if you are pregnant, think you might be pregnant or plan on becoming pregnant. Speak to your doctor for further advice.
If you become pregnant while using Epiduo, inform your doctor as soon as possible as the treatment will need to be stopped.
Epiduo can be used by women who are breastfeeding, though you should avoid your child coming into contact with the treatment. For this reason, application of Epiduo to the chest should be avoided by breastfeeding mothers.
If you would like to know more about the safety of Epiduo during pregnancy or while breastfeeding, speak to your doctor or a pharmacist.
Always seek your doctor's advice before you buy Epiduo online from Prescription Doctor.
Please inform our doctors of all medicines you are currently taking, including those prescribed by your GP or bought over the counter from a pharmacy, as well as health and herbal supplements.
Do not use Epiduo past the expiry date printed on the packaging. The date refers to the last day of the specified month.
Never throw away medicine via household or water waste. Take any unwanted or expired medication to your local pharmacy and ask them to discard it safely on your behalf.
Always store medicine out of sight and reach from children and pets.
Never share your Epiduo gel with anybody else, even if they are experiencing the same symptoms or have been diagnosed with the same condition as you.
If you forget to use Epiduo gel when you should, use it as soon as you remember. If it is nearly time for your next dose, skip the missed dose and continue taking your medicine as normal.
Do not use more Epiduo gel to make up for the missed application.
Epiduo should not impact your ability to drive or operate machinery.
Yes, you can drink alcohol in moderation while using Epiduo gel. Always adhere to the recommended limit of 14 units of alcohol per week.
Epiduo gel should not impact your contraceptive pill. For further information about the use of Epiduo while taking other medicines, speak to your doctor or a pharmacist.
You can use moisturisers on your skin once the Epiduo gel has been absorbed by your skin. Wait for the area of the skin to become dry before applying a moisturiser.
Before applying make-up, ensure the treated area is dry. If you are going to apply make-up in the morning, use Epiduo before you go to bed. Avoid make-up which may have a drying effect on your skin.
Do not use other products which contain adapalene or benzoyl peroxide while using Epiduo. Avoid using peels which contain salicylic acid or glycolic acid while using Epiduo gel, as this can cause further irritation or adverse effects. Before using any other acne treatment with Epiduo gel, speak to your doctor.
Table of contents
How does Epiduo work for acne?
Epiduo side effects and cautions
Additional resources
Natural ways to control your acne.
Control your hormones, control your acne
References
NHS, 2019. Acne: Overview, causes, diagnosis, treatment, complications.
British Association of Dermatologists (BAD), 2020. Acne.
Galderma, 2020. Epiduo 0.1%/2.5% Gel: Summary of Product Characteristics
© 2013 - 2020 Al Muhsineen Limited. All Rights Reserved. Registered Pharmacy: 34 Halliwell Road, Bolton BL1 8RL. Registered Office: 254 First Floor, Shearbrow, Blackburn, England, BB1 8DS
Impressum: Mr Mohamed Imran Lakhi, M Pharm, Adil Bhaloda, M Pharm (Clinical Director).
