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About Product
Mohamed Imran Lakhi
This content has been written and checked for quality and accuracy by
Mohamed Imran Lakhi Content Administrator GPhC: 2060586 Updated on: 01/04/2021 Next review: 01/10/2021

What is Zineryt lotion for?

Zineryt lotion is a topical acne treatment which contains an antibiotic called erythromycin.

The antibiotic kills the bacteria associated with acne, allowing the skin to naturally heal itself. The chemical complex contains zinc to help the skin absorb the medicine and improve its healing capabilities.

Unlike acne creams, Zineryt does not come ready-made. Our pharmacist will pre-mix the chemicals before sending it to you. Once mixed, the medicine has a shelf life of between 5 and 8 weeks.

Where can I buy Zineryt?

Zineryt is available to buy online from Prescription Doctor's online pharmacy. Simply fill out our online medical form for our doctor to review. If your order is approved before 3pm, a prescription for Zineryt will be issued for our UK based pharmacy to fulfil.

Our GPhC registered pharmacy will dispatch your item to your preferred address the same day for a next-day delivery. We ship all items in discreet packaging to ensure patient confidentiality.

Zineryt is a prescription-only medicine and is not available to buy over the counter.

What causes acne?

There are numerous factors which can influence acne, with hormones being a major contributor. During puberty, when hormones like testosterone and progesterone begin to rise, acne may start to occur.

Some women may experience acne before their period or during the first few months of pregnancy, when progesterone levels are at their highest. Though the exact mechanism of how progesterone causes acne is not known, it is believed that high progestogen levels influence acne.

Aside from hormonal changes, acne can also simply be hereditary. In general, the common risk factors for the development of acne include:

  • Smoking
  • Cosmetics (make-up may clog pores)
  • Medications (side effect)
  • Genetics
  • Pregnancy
  • Menopause

If you suspect that your acne is a side effect of a medication you are currently taking, speak to your doctor. You should not stop taking a medicine your doctor has prescribed, without first consulting your doctor.

Acne can have an affect on your mental health. If your acne is causing you distress, speak to your doctor.

Your doctor can discuss with you about the most suitable course of treatment for you, including over-the-counter medicines or prescription acne creams. They may also be able to help you identify factors which might be worsening your symptoms, such as cosmetic products or medicines.

How does acne develop?

Acne starts to develop when a pore becomes clogged. This blockage prevents sebum from escaping.

Sebum is an oily substance which forms a protective barrier on the skin's surface. It is secreted from sebaceous glands, which lie just below the surface of the skin.

If a pore becomes blocked, the sebum has nowhere to go, so it builds up below the epidermis.

Bacteria, called Propionibacterium acnes, feed on this build-up of sebum and thrive. These bacteria excrete chemicals which irritate the surrounding tissues and cause inflammation.

How acne develops under the skin

Combined with the surplus of sebum, the inflammation causes red, swollen bumps to form on the skin. These can be painful, itchy or dry.

In most cases, these spots are small and go away on their own within a week or so. But for some people, acne can be a severe and distressing condition which affects them both physically and mentally.

Moderate to severe acne is often characterised by a large amount of blackheads, whiteheads, nodules and cysts. It is often diagnosed based on the clinical image (how the condition looks) by a doctor.

It is important to speak to your doctor about your condition, especially if it is causing you distress. Your doctor will be able to discuss possible treatment options with you, such as over-the-counter or prescribed medicines.

It's important not to pick, squeeze or scratch your acne. Doing so can create an open wound which is more susceptible to infection. Aside from infection, scarring can occur from picking or squeezing spots.

How does Zineryt lotion work against acne?

Zineryt contains two key ingredients - an antibiotic called erythromycin and zinc.

Erythromycin kills the bacteria associated with acne. These bacteria thrive on the surplus of sebum which builds up in clogged skin pores. They excrete chemicals which irritate the skin and cause inflammation.

By reducing the amount of bacteria and their harmful excretions, the affected skin area is able to heal quicker.

Zinc is believed to help the skin to heal faster and is used in a wide number of treatments for all manner of ailments, including dressings for wounds.

Together, the two key ingredients of Zineryt help to significantly reduce acne, bringing relief from this debilitating condition.

How to apply Zineryt lotion?

Zineryt comes as a dry powder and a solvent which need to be mixed together before you can use it. Our pharmacist will mix the solution for you before they send it, so that it's ready to use right away.

The bottle comes with a special applicator pad built into the cap. The applicator pad makes it easier to evenly apply the lotion to your skin, using the following steps:

  1. Remove the cap to expose the applicator.
  2. Tip the bottle upside down, so that the pad is facing downwards. This flows the solution in the pad evenly. Do not squeeze the bottle when you do this.
  3. Hold the pad against your face or skin and gently spread the solution over the infected area. Make sure you cover all the affected areas evenly. You can increase the flow of the lotion by pressing the pad against your skin. Do not squeeze the bottle.
  4. Once you have applied Zineryt lotion, replace the cap, ensuring it is firmly affixed to the bottle.

Apply the solution twice daily. Avoid contact with the eyes, nose and mouth.

If you apply too much Zineryt, simply wipe it off with a tissue.

Let the Zineryt lotion dry before applying make-up, moisturisers or other skincare products, including other topical treatments.

If no improvement is seen within 8 weeks, or if acne worsens, stop using Zineryt and speak to your doctor.

If you are unsure on how to use Zineryt, consult the patient information leaflet enclosed with your medicine. If you still aren't sure, ask your doctor or a pharmacist.

How long does Zineryt take to work?

It may take between 10 and 12 weeks of treatment with Zineryt for acne to clear up. If your acne returns, you may be able to restart treatment with Zineryt. Consult your doctor before restarting treatment.

What should I do if I forget to apply Zineryt lotion when I should?

If you forget to apply Zineryt lotion when you should, use it as soon as you remember.

Do not apply more Zineryt lotion to make up for the dose you missed. Leave 3 hours before you use it again.

What should I do if I apply too much Zineryt lotion?

If you accidentally apply too much Zineryt lotion, wipe the excess away with a tissue.

Zineryt side effects and cautions

All medicines carry the risk of side effects. It is important to educate yourself on the possible side effects of the medication you are taking so that you can identify a problem and consult a medical professional.

You can view the patient information leaflet for Zineryt online as a PDF, which you can download or print off if you need to.

Zineryt is generally well tolerated and side effects are uncommon, affecting 1 in 1000 people. You may or may not experience the side effects listed below.

Possible side effects of taking Zineryt include:

  • Itching
  • Rash
  • Swelling of the mouth, face, lips or tongue
  • Difficulty breathing

This is not an exhaustive list of side effects associated with Zineryt lotion. Further information regarding the safety of Zineryt, including a complete list of side effects, can be found within the patient information leaflet, enclosed with your medicine.

If you experience any side effects after using Zineryt, report them to your doctor or call NHS 111 for advice.

Pregnancy and breastfeeding

Zineryt is safe to use when pregnant, but should be used with caution when breastfeeding.

If you are breastfeeding, do not apply the solution to the chest area. Consult with your doctor for further advice.

Allergic reaction

Do not take Zineryt if you are allergic to Erythromycin, zinc or any of the other ingredients listed in the patient information leaflet.

If you experience an allergic reaction to Zineryt, stop taking the medicine and seek immediate medical attention by going straight to your nearest accident and emergency department. Take the medicine and packaging with you so the doctors know exactly what you have taken.

Signs of an allergic reaction include:

  • Chest tightening
  • Dry, red and cracked skin
  • Itchy, red watery eyes
  • Raised, itchy, red rash (hives)
  • Swelling of the lips, tongue, eyes or face
  • Tummy pain, nausea, vomiting or diarrhoea
  • Wheezing

Other safety information

Always seek your doctor's advice before you buy Zineryt lotion online from Prescription Doctor.

Please inform our doctors of all medications you are currently taking, including those prescribed by your doctor or bought over the counter, such as health and herbal supplements.

Do not take Zineryt past the expiry date. Unlike other medicines, the expiry date of Zineryt is not marked on the packaging.

Zineryt should be discarded 8 weeks after it is made-up. You should set a reminder on your phone, or mark a date in a calendar to remind you to throw away the expired medicine.

Never throw away medicine via household or water waste. Take any unwanted or expired medication to your local pharmacy and ask them to dispose it safely on your behalf.

Always store medicine out of sight and reach from children and pets.

Never share your medicine with anybody else, even if they have the same symptoms or have been diagnosed with the same condition as you.

Frequently asked questions

Can I drink alcohol while using Zineryt?

It is safe to drink alcohol while using Zineryt lotion. Always drink in moderation and avoid drinking more than the recommended 14 units of alcohol per week.

Will Zineryt affect my ability to drive or operate machinery?

Zineryt lotion is unlikely to impact your ability to drive or operate machinery.

Will Zineryt affect my contraceptive pill?

It is unlikely that Zineryt lotion will affect your contraceptive pill.

Does Zineryt contain benzoyl-peroxide?

No, Zineryt lotion does not contain benzoyl-peroxide. A full list of ingredients in Zineryt can be found within the patient information leaflet.

When should I stop using Zineryt?

Your doctor will determine when you should stop using Zineryt lotion. It is important to keep applying Zineryt lotion for as long they have prescribed it to you.

When does Zineryt expire?

Zineryt lotion expires 8 weeks after it has been made. You should not use Zineryt lotion after these 8 weeks. Discard of the medicine in accordance with your local guidance, even if you have medicine left.

Can Zineryt cause hair loss?

Hair loss is not listed as a side effect of Zineryt. If you have any concerns about any of the side effects listed in the patient information leaflet, speak to your doctor.

Can Zineryt lotion cause thrush?

Some people may experience thrush after taking antibiotics, such as erythromycin. However, it is unlikely that Zineryt lotion will cause thrush. If you do develop thrush while using Zineryt, speak to your doctor or ask a pharmacist for advice.

Can I buy Zineryt online?

You can buy Zineryt online from Prescription Doctor following an online consultation. Simply complete our online medical form for one of our doctors to review and, if our doctor deems the treatment appropriate, our UK based pharmacy will dispense and dispatch your item the same day, for a next-day discreet delivery service.

Table of contents

What is Zineryt lotion for?

What causes acne?

How does Zineryt lotion work against acne?

How to use Zineryt

Zineryt side effects and cautions

Frequently asked questions

Additional resources

10 foods to avoid if you want clear skin

How to use tea tree oil for acne

What causes 'bacne' and how is it treated?

Natural ways to control your acne

Control your hormones; control your acne


NHS, 2019. Acne: Overview, causes, diagnosis, treatment, complications.

British Association of Dermatologists (BAD), 2020. Acne.

Leo Laboratories Ltd., 2018. Zineryt powder and solvent for cutaneous solution: Summary of Product Characteristics

Treatment information

  • Product Name: Zineryt
  • Active Ingredient(s): Erythromycin (40 mg/ml) and zinc acetate (12 mg/ml)
  • Manufacturer: Astellas Pharma
  • Administration: Apply to affected area
  • Presentation: Solution Bottle
  • Available Strength: 30ML and 90ML erythromycin (40 mg/ml) and zinc acetate (12 mg/ml)
  • Exemption: Prescription only medication
  • Application: Men and women over 18 with acne
  • Dosage: Twice daily to acne affected area
  • Description: Zineryt solution is a topical acne treatment containing the antibiotic erythromycin.
  • Drug Class: Antibiotic
  • Alcohol Consumption: No influence
  • When Pregnant: Safe to take while pregnant.
  • When Breastfeeding: Do not apply on chest area while breastfeeding.
Click here to view the Zineryt - Patient Information Leaflet

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