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Omeprazole
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Treatment Information
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Table of contents
What is Omeprazole?
Omeprazole is a proton pump inhibitor or antacid. It is used for the treatment of several conditions of the stomach and oesophagus resulting from too much acid in the stomach. Omeprazole is typically used to treat frequent heartburn and gastro-oesophageal reflux disease (GORD) and is available under a range of brand names, including Losec and Prilosec.
By inhibiting proton pumps in stomach-lining cells, omeprazole prevents excessive acid secretion, thus treating conditions such as:
- Heartburn
- Acid reflux
- Indigestion
- Stomach ulcers
- Gastro-oesophageal reflux disease (GORD)
- Zollinger-Ellison syndrome
Understanding Heartburn?
Heartburn is a primary symptom of acid reflux and GORD. It occurs when stomach acid flows back into the oesophagus, resulting in a burning sensation in the chest. The backflow of acid has easy passage if the lower oesophageal sphincter is weakened, which means it easily relaxes and opens up.
Acid reflux can be quite painful and uncomfortable. If left untreated, frequently recurring acid reflux may cause severe damage to the oesophageal tissue.
Symptoms of heartburn include:
- Burning pain in the chest
- Pain at the back of the throat
- Recurrent coughing or hiccups
- Sour taste in the mouth
While acid reflux itself is not a serious condition, stomach acid can damage the cells in the oesophagus, which carries risks of further complications, such as Barrett's oesophagus. Speak to your doctor if you are concerned about developing Barrett's oesophagus as a result of chronic GORD.
There are steps you can take to prevent heartburn from developing, such as:
- Avoid foods that might trigger heartburn or indigestion.
- Avoiding lying down straight after a meal
- Eating your food slowly
- Reduce the amount of food you eat before bed
Other possible causes of heartburn include:
- Anti-inflammatory medicines (such as Ibuprofen)
- Pregnancy
- Smoking
- Stress
If you suspect a medication you are taking is causing acid reflux, speak to your doctor or ask a pharmacist for advice. They may be able to prescribe or recommend a heartburn treatment for you, like Omeprazole.
How Does Omeprazole Work?
Omeprazole is a proton pump inhibitor (PPI) that blocks cells in the lining of the stomach, which reduces the amount of acid produced in the stomach.
By reducing the amount of acid produced by the stomach, Omeprazole reduces the chances of acid reflux occurring.
How Do I Take Omeprazole?
Your doctor will determine a suitable starting dose of Omeprazole for you and how frequently you should take it.
Always follow the doctor's prescription when taking Omeprazole.
The recommended dose, unless prescribed otherwise by your doctor, is as follows:
- 10 mg once a day for 4-8 weeks if the gullet has not been damaged
- 20 mg once a day for 4-8 weeks for a slightly damaged gullet. This dosage will be lowered to 10 mg a day after the gullet heals.
When Should I Take Omeprazole?
You should take Omeprazole in the morning, with or without food.
Omeprazole capsules should be swallowed whole with a glass of water.
The doctor may increase or lower the dosage depending on how you respond to the treatment.
What Should I Do If I Forget to Take Omeprazole?
If you forget to take Omeprazole when you should, take it as soon as you remember.
Do not take more Omeprazole to make up for a missed dose.
What Should I Do If I Take More Omeprazole Than I Should?
Speak to your doctor or pharmacist right away if you accidentally take more Omeprazole than prescribed.
Taking more Omeprazole than you should is unlikely to treat your condition any more effectively but may increase your risk of side effects.
If you are unsure how much Omeprazole you should take, ask your doctor or consult the patient information leaflet.
Omeprazole Side Effects and Cautions
Before taking Omeprazole, we encourage you to read the patient information leaflet (PIL) enclosed with your medicine.
The patient information leaflet contains important information about taking and storing Omeprazole, including a complete list of side effects, ingredients, and instructions on what to do if you experience an allergic reaction.
You can view the patient information leaflet for Omeprazole online.
Omeprazole Allergies
Do not take Omeprazole if you are allergic to any of the ingredients used to make Omeprazole or are allergic to any other medication belonging to the proton pump inhibitor (PPI) class, such as lansoprazole.
If you experience any signs of an allergic reaction, stop taking Omeprazole and speak to your doctor urgently. If you experience a severe reaction, go straight to your nearest A&E department immediately. Take the medicine and packaging with you so the doctors can assess what you took and how much you took.
Signs of an allergic reaction may include:
- Swelling of the lips, face, tongue and throat
- Difficulty breathing
- Difficulty swallowing
- Raised, lumpy rash (hives)
Who Should Not Take Omeprazole?
Omeprazole may not be suitable for you. If you are unsure whether this medicine is safe for you, ask one of our doctors or a qualified pharmacist for advice.
Do not take Omeprazole if you are currently on any medication containing nelfinavir.
Omeprazole may affect the effectiveness of other medicines. Ensure that you speak to your doctor about any medication you are currently taking, including those bought over-the-counter, on prescription, and health or dietary supplements.
Omeprazole During Pregnancy and Breastfeeding
If you are pregnant, think you might be pregnant, or plan on becoming pregnant soon, speak to your doctor or a pharmacist for advice on whether the benefits of this medicine outweigh any potential risks posed to you or your unborn child.
Inform our doctor if you are breastfeeding, so they can determine whether this medicine is safe for you.
Omeprazole Side Effects
All medicines carry the potential risk of side effects, though not everybody gets them. Before you begin your treatment with any medicine, you should familiarise yourself with the side effects listed in the patient information leaflet (PIL) enclosed with your medicine.
Common side effects of Omeprazole may include:
- Benign stomach polyps
- Constipation
- Diarrhoea
- Flatulence
- Headache
- Nausea
- Stomach ache
- Vomiting
Uncommon Omeprazole side effects may include:
- Changes in blood tests that check how the liver works
- Dizziness
- Fatigue (tiredness)
- Fracture of the hip, wrist, or spine.
- Generally feeling unwell (malaise)
- Insomnia
- Itchy, raised, lumpy rash (Hives)
- Swelling of the feet and ankles
- Tingling of the extremities (pins and needles)
- Vertigo (spinning sensation)
Rare Omeprazole side effects may include:
- Agitation
- Blurred vision
- Change in the sensation of taste
- Changes in mood
- Confusion
- Decreased levels of sodium in the blood, causing cramps, vomiting and weakness.
- Depression
- Dry mouth
- Hair loss
- Increased perspiration (sweating)
- Inflammation inside the mouth
- Joint and muscle pain
- Liver problems, including jaundice (Dark urine, tiredness and yellowing of the skin)
- Reduced number of white blood cells or platelets, causing symptoms such as bruising, increased risk of infection, and weakness.
- Sensitivity to sunlight
- Thrush
- Wheezing or shortness of breath
This is not an exhaustive list of side effects. For more information regarding the safety of this medicine, please refer to the patient information leaflet (PIL) enclosed with your medicine.
If you experience any side effects, whether listed above or in the patient information leaflet, report them to your doctor or pharmacist for advice.
Always store Omeprazole out of reach from children and pets.
Never share your medicine with anyone else, even if they are experiencing the same symptoms as you.
Where Can I Buy Omeprazole Online in the UK?
If you're considering purchasing Omeprazole online in the UK, it's essential to opt for a reliable and authorised online pharmacy. Prescription Doctor offers a secure and user-friendly platform where you can consult with healthcare professionals and order Omeprazole in various dosages.
Prescription Doctor: A Safe Way to Order Omeprazole with Discreet Packaging
Ordering Omeprazole through Prescription Doctor guarantees that you receive authentic medication from a trusted source. Our platform streamlines the process, from online consultation to discreet, tamper-proof packaging, ensuring your confidentiality.
Frequently Asked Questions About Omeprazole
Can I Buy Omeprazole Over the Counter?
Omeprazole is a prescription-only drug and is not available over the counter. However, you can buy Omeprazole online from Prescription Doctor following an online consultation with one of our doctors.
Will Omeprazole Affect My Ability to Operate Machinery or Drive?
It is very unlikely that Omeprazole will affect your ability to drive or operate machinery. Do not do either if you experience dizziness, blurred vision, or any other side effect that may affect your judgement.
Can I Drink While Taking Omeprazole?
While it is unlikely that alcohol will react with Omeprazole, you should avoid or limit alcohol consumption as it may worsen heartburn.
Will Omeprazole Affect My Contraception?
Omeprazole is unlikely to affect hormonal contraceptives, including the emergency contraceptive. If you vomit after taking Omeprazole, check the patient information leaflet supplied with your contraceptive pill for instructions on what to do.
How Long Does Omeprazole Take to Work?
Omeprazole starts to work within 2 or 3 days of taking it. However, it can take up to 4 weeks for Omeprazole to reach its maximum effectiveness.
Is Long-Term Use of Omeprazole Safe?
Taking Omeprazole - or any other proton pump inhibitor - for longer than 1 year may increase your risk of fracture to the wrist, hip or spine. If you have any concerns about taking Omeprazole for a long period, speak to your doctor or ask a pharmacist for advice.
How Can I Stop Taking Omeprazole?
You should speak to your doctor before ceasing treatment with Omeprazole. Stopping treatment for acid reflux may cause your symptoms to come back.
Can I Take Omeprazole with Gaviscon?
You can take Omeprazole with antacids like Gaviscon. However, you should leave at least 2 hours between taking Omeprazole and an antacid. If you are unsure whether you can take Omeprazole alongside another medication, speak to your doctor or a pharmacist for advice.
Can Omeprazole Cause Constipation?
Constipation is listed as a side effect of Omeprazole. If you experience constipation while taking Omeprazole, speak to your doctor or a pharmacist for advice on what you can do. Keeping hydrated by drinking plenty of water throughout the day can help to prevent constipation.
Additional Resources
Sources
NHS, 2018. Omeprazole.
Mylan, 2017. Summary of Product Characteristics: Omeprazole 10 Mg Gastro-Resistant Capsules, Hard
Treatment information
- Product Name: Omeprazole
- Active Ingredient(s): Omeprazole
- Administration: Oral
- Presentation: Tablets
- Available Strength: 10 mg, 20 mg and 40 mg
- Exemption: Prescription only
- Application: Men and women over 18+
- Dosage: Take 10 mg once daily
- Description: Omeprazole is a heartburn treatment which works by reducing the amount of acid in the stomach
- Drug Class: Proton pump inhibitor
- Alcohol Consumption: Avoid or limit alcohol consumption
- When Pregnant: Tell our doctor if you are pregnant, think you might be pregnant, or plan on becoming pregnant before taking Omeprazole
- When Breastfeeding: Tell our doctor if you are breastfeeding before taking Omeprazole
- Price: 9.99 GBP
Click here to view the Omeprazole - Patient Information Leaflet
Authored By
Adil Bhaloda
Content Administrator
Adil provides governance for the online services, overseeing prescription dispensation in line with UK pharmacy standards.
Published on: 24/05/2019
Published on: 24/05/2019
Reviewed By
Mohamed Imran Lakhi
MPharm - Lead Pharmacist
Imran Lakhi is the superintendent pharmacist and founder at Prescription Doctor. He has been at the core of our team.
Reviewed on: 13/03/2024
Reviewed on: 13/03/2024
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Heartburn Alternatives
Lansoprazole
- Reduces stomach acid
- Taken once daily
- Relieves heartburn symptoms quickly
Nexium (Esomeprazole)
- Prevents heartburn
- Lasts 24 hours
- Can be taken with or without food
Losec
- Treats heartburn and GORD
- Capsules or tablets
- Consultation with medical professional
Pantoprazole
- Easy to swallow tablet
- Taken once daily
- Treats and prevents heartburn symptoms
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