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  3. Choose delivery method and mode of payment.
  4. Our team of expert prescribers will assess whether medication is suitable.
  5. If you get the green light and it is deemed suitable, your order will be processed quickly and efficiently.
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We deliver medications between Monday and Saturday. You can upgrade to Saturday delivery on Friday.

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Payment Methods
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You can pay for your order using credit, debit card and bank transfer.

Card Payment: Please notify us that you wish to cancel your order. Your refund will show available In 1 - 3 days.

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About Product
This content has been written and checked for quality and accuracy by
Mohamed Imran Lakhi Content Administrator GPhC: 2060586 Updated on: 28/06/2019 Next review: 28/12/2019

What is Solpadol?

About Solpadol

For severe pain that painkillers aren't touching, Solpadol can be an effective short-term pain reliever.

Solpadol is a painkiller which contains traditional paracetamol and codeine.

While the mechanism behind paracetamol is not well understood, it is believed that it inhibits the production of the prostaglandins which relay pain signals through the nervous system.

Codeine is an opioid derived from poppy plants. When metabolised by the liver, it is converted into morphine which blocks pain signals from being sent to and from the brain.

What are the active ingredients?

  • 500 mg Paracetamol
  • 30 mg Codeine Phosphate.

What is Solpadol used for?

Solpadol can be used to treat:

  • Arthritis
  • Sciatica
  • Joint issues
  • Toothache
  • Post-operative pain
  • Nerve damage
  • Sporting injuries.

How does Solpadol work?

The codeine in Solpadol interacts with the central nervous system (CNS), changing the way the brain perceives pain. Codeine mimics the action of pain-reducing chemicals, known as endorphins, naturally occurring in the brain and spinal cord.

The human body converts codeine into morphine. The morphine molecules latch onto opioid receptors in the CNS, which causes receptors to send pain-reducing messages to the brain.

Paracetamol works in the CNS to inhibit the production of prostaglandins, which are naturally occurring chemicals that produce pain and inflammation at the site of injury or disease.

The analgesic effects of Solpadol typically begin 30 to 45 minutes after consumption.

How do I take Solpadol?

Solpadol is for adults, who should take one or two tablets every four to six hours with a glass of water, or as prescribed. Consumers should not take more than two tablets at a time, take more often than every four hours, or take more than eight tablets in 24 hours.

Consumers should not take Solpadol for more than three days, as the risk of physical dependence increases with prolonged use.

Paediatric population

Solpadol is not suitable for children.

What are the uses, dosage, side effects & warnings?


Solpadol provides short term relief from severe pain in adults. Prescribers will issue the correct dosage for each patient, depending on the severity and source of their pain as well as their medical history. Solpadol is not appropriate for everyone.


Follow the guidance of the doctor. Do not exceed prescribed dose.

Missed doses / Overdoses

Since consumers take Solpadol as needed, missed doses are not an issue.

If a consumer takes more Solpadol than they should, they must consult with a physician immediately even if they feel well. High paracetamol levels can cause delayed but serious liver damage. The risk of paracetamol overdose is greater in people with alcoholic liver disease.

Side effects

As with all medications, Solpadol may cause adverse reactions for some consumers. Some adverse effects may be serious. Consumers of Solpadol should seek immediate medical attention if they experience any of the following:

  • Symptoms of an allergic reaction, such as swelling of the lips, face or neck, difficulty breathing, skin rash or hives
  • Severe back or abdominal pain

Solpadol may cause side effects that are not serious but warrant the attention of a physician if the side effects worsen or persist for longer than a few days:

  • Constipation.
  • Drowsiness.
  • Nausea, vomiting, abdominal pain, anorexia, incontinence, diarrhoea.
  • Skin rash, itching.
  • Sweating, facial flushing.
  • Low body temperature.
  • Dry mouth.
  • Disturbances in vision.
  • Pin-point pupils.
  • Malaise, tiredness.
  • Headache.
  • Fever.
  • Dizziness, vertigo, light-headedness.
  • Slow or rapid heartbeat, palpitations.
  • Breathing difficulties.
  • Low blood pressure, feeling faint upon standing from a seated or lying position.
  • Confusion, anxiety, mood changes such as including depression, sadness, euphoria.
  • Convulsions, hallucinations, nightmares, depression.
  • Stomach cramps, enlargement of the spleen.
  • Uncontrolled muscle movement or muscle rigidity.
  • Pain or difficulty in passing urine.
  • Increased or decreased urinary frequency.
  • Decreased libido or potency, or weak erection in males.
  • Restlessness.
  • High blood glucose levels.
  • Swelling of the lymph nodes.
  • Kidney damage.
  • Blood disorders, such as reduced platelets that increase the risk of bleeding or bruising, reduced white blood cells that increase the risk of infection, and a severe decrease in blood cells to cause weakness, bruising and increased risk of infection.

Warning: Solpadol and pregnancy

If you are pregnant or breastfeeding, it is strongly advised against using Solpadol unless under the direction of a physician.

How to store Solpadol?

Keep Solpadol and all medications out of the sight and reach of children. Keep medicine stored below 25 degrees Celsius. Store Solpadol in its original packaging. Do not use Solpadol after the expiry date printed on the packaging.

Cautions and exclusions

To reduce the risk of drug interactions, consumers should notify prescribers of their current medications and medical conditions.

Solpadol contains paracetamol 500 mg and codeine phosphate hemihydrate 30 mg. Solpadol may include stabilizers and other ingredients. Do not use Solpadol if you are allergic or intolerant to any of the ingredients.

Frequently asked questions

How long does it take for solpadol to work?

Generally, solpadol begins to work between 30 and 60 minutes after ingestion. The effects of solpadol last for around 4 to 6 hours.

The time it takes for the effects to become noticable may differ depending on the individual.

What are the benefits of effervescent tablets?

Effervescent tablets are dissolved into water rather than swallowed.

If you have trouble swallowing tablets, you may prefer effervescent tablets.

Is solpadol the same as solpadeine max?

On the surface, it's easy to presume that solpadeine max and solpadol are the same - even their names sound alike. While they share the same ingredients and similar names, there are a couple of key differences.

Solpadeine max contains less than half the amount (around 12 mg) of codeine phosphate than solpadol. They are indicated for mild to moderate pain in adults whose pain has not responded to traditional painkillers. Solpadeine is classed as a pharmacy medicine. This means that they can only be bought from licensed pharmacies and the acquisition of the medicine must be supervised by a qualified doctor or pharmacis

Solpadol contains 30 mg of codeine - more than twice the amount found in solpadeine max. They are indicated for moderate to severe pain in adults and are only available on prescription.

Why is Codeine Addictive?

Codeine addiction can be both physical and psychological. With repeated use, the body becomes accustomed to the drug. Withdrawal symptoms may occur once it is no longer present in your system. A psychological urge to recreate the feeling associated with codeine phosphate may remain long after the medication is gone.

If addiction is a concern, speak to your GP or visit for more advice.

Table of contents

What is Solpadol?

How to store Solpadol?

Solpadol and pregnancy

Side effects

What are the uses, dosage, side effects & warnings?

How do I take Solpadol?

How does Solpadol work?

What are the active ingredients?

Frequently asked questions

Related information

What are the dangers of codeine?

How to treat sprains and strains

What's the right painkiller for me?

Treatment information

  • Product Name: Solpadol
  • Manufacturer: Sanofi
  • Active Ingredient(s): Codeine Phosphate and Paracetamol
  • Administration: Oral
  • Presentation: Tablets
  • Available Strength: 30/500 mg
  • Exemption:Prescription only medication
  • Application: Men and women over 18
  • Dosage: Take one to two - every six to eight hourly as needed
  • Description: Pain Relief
  • Drug Class: Opioid (Analgesic)
  • Alcohol Consumption: Do not drink alcohol while taking Solpadol
  • When Pregnant: Do not consume Solpadol
  • When Breastfeeding: Do not consume Solpadol
Click here to view the Solpadol - Patient Information Leaflet

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